T-cell receptor sequencing generated from 189 blood samples taken upon CRPC diagnosis in patients in-cluded in the CROC project. DNA was isolated from PBMCs. Dataset includes raw files and TCR clones gen-erated from MiXCR.
Glud et. al. The Blood T-cell Receptor Repertoire is an Independent Prognostic Marker in Patients with Castration Resistant Prostate Cancer.
External researchers (academic or commercial) interested in analysing the prostate dataset will need to con-tact the Data Access Committee via email to kdso@clin.au.dk. The Data Access Committee is formed of Karina Dalsgaard Sørensen, Michael Borre, and Ole Halfdan Larsen (Department of Clinical Medicine, Aarhus Uni-versity). Due to Danish Law, for the authors to be allowed to share the data (pseudonymised) it will require prior approval from The Danish National Committee on Health Research Ethics (or similar) for the specific new research goal. The author (based in Denmark) has to submit the application for ethical approval, with the external researcher(s) as named collaborator(s). In addition to ethical approval, a Collaboration Agree-ment and a Data Processing Agreement is required, both of which must be approved by the legal office of the institution of the author (data owner) and the legal office of the institution of the external researcher (data processor).