Publications

This page lists known publications where GenomeDK was used for some or all of the data analysis. The list is updated approximately once a year. If you think a publication is missing or should not have been included, please let us know.

1079 publications listed, last updated on 2026-06-26.

2026

(45 publications)

Vanthournout, B., Dahirel, M., Chuang, A., De Wolf, K., D’haenekint, N., Abihssira-Garcia, I. S., Alicea-Serrano, A. M., Andersen, M., Anderson, H., Aviles, L., Barnett, J. B., Başarır, E., Beatman, T. R., Bechsgaard, J., Bilde, T., Biundo, C. E., Boles, J. C., Brandt, E. E., Chakraborty, S., et al. (2026). Urbanization effects are trait-specific and city-dependent across a widespread spider’s global range. https://doi.org/10.64898/2026.06.19.733406
Pankratov, V., Meyer Pedersen, B., Sørensen, E. F., Munch, K., Bataillon, T., Schierup, M. H., & Bergman, J. (2026). A Curated Genome-Scale Nucleotide Diversity Panel of Non-Human Primates. https://doi.org/10.64898/2026.06.16.732573
Beck, S. E., Deak, J. D., Levey, D. F., Ge, T., Jeffries, P. W., Lai, D., Mallard, T. T., Degenhardt, L., Lind, P. A., Tollerup Nielsen, T., Tubbs, J. D., Wetherill, L., Johnson, E. C., Hatoum, A. S., Børglum, A. D., et al. (2026). Multi-ancestry genome-wide association study and meta-analysis of stimulant use disorder reveals biology and relationships to other psychiatric disorders. https://doi.org/10.64898/2026.06.05.26354997
Diekema, M. H., Rasmussen, M. H., Drue, S. O., Frydendahl, A., Andersen, C. L., & Pedersen, J. S. (2026). Error modelling of SNVs and indels in deep targeted cell-free DNA for sensitive detection of tumor burden in colorectal cancer. https://doi.org/10.64898/2026.05.29.728727
Zamani, F., Rasmussen, A. M., Schuster, V., Diekema, M. H., Krogh, A., & Pedersen, J. S. (2026). miDGD: a multi-modal deep generative model predicts microRNA expression from bulk or single-cell mRNA expression. https://doi.org/10.64898/2026.05.29.727918
Jin, Y., Guo, Y., Koller, J. M., Grossen, S. C., Uhlmann, A., Forde, N. J., Zouki, J.-J., Torrecuso, R., Mueller, K., Martin-Rodriguez, J. F., Franco-Rosado, P., Grothe, M., Cramer, C., Büning, A. K., Eichele, H., Palmucci, S., Prato, A., Saia, F., Tommasin, S., et al. (2026). Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders. https://doi.org/10.64898/2026.05.16.26353368
Santos Junior, D. R. d., Fè, D., Lenk, I., Jensen, C. S., Asp, T., Janss, L., & Bornhofen, E. (2026). Genomic prediction of single cross families of perennial ryegrass in two nitrogen managements. https://doi.org/10.64898/2026.05.05.722839
Leyi, Z., Seiler, C., Speed, D., Micheroli, R., & Ospelt, C. (2026). SNPic: SNP Topic Modeling for Interpretable Clustering of Complex Phenotypes. https://doi.org/10.64898/2026.04.22.720106
Yu, D., Strom, N. I., Gerring, Z. F., Topaloudi, A., Halvorsen, M. W., Shekhar, S., Miller-Fleming, T. W., Tang, M., Porras, L. M., Ivankovic, F., Mahjani, B., Palviainen, T., Corfield, E. C., Androutsos, C., Apter, A., Ask, H., Baglioni, V., Ball, J., Barr, C. L., et al. (2026). Genome-Wide Association Analysis of Tic Disorders Reveals 6 Independent Risk Loci and Highlights Tic-Associated Cell Types and Brain Circuitry. https://doi.org/10.64898/2026.04.09.26350245
Moslemi, C., Folgoas, M., Yu, X., Jensen, J. D., Hentrup, S., Li, T., Wang, H., Boelt, B., Asp, T., Sibout, R., & Ramstein, G. P. (2026). In vivo validation of predicted fitness effects at single-base resolution in a Brachypodium distachyon mutant population. https://doi.org/10.64898/2026.03.31.715642
Lin, Y., Oroperv, C., Boll Johansen, A. F., Rasmussen, M. H., Andersen, C. L., & Besenbacher, S. (2026). Combining mutation detection with fragmentomics features leads to improved tumor-informed ctDNA detection. https://doi.org/10.64898/2026.03.30.714025
Diepeveen, E., Riera Bellés, M., & Schierup, M. H. (2026). Pervasive positive selection on X-linked ampliconic genes in primates. https://doi.org/10.64898/2026.03.09.710536
Vahedi Torghabeh, B., Moslemi, C., Jensen, J. D., Hentrup, S., Li, T., Yu, X., Wang, H., Asp, T., & Ramstein, G. P. (2026). Genomic language models improve cross-species gene expression prediction and accurately capture regulatory variant effects in Brachypodium mutant lines. https://doi.org/10.64898/2026.02.27.708524
Kjærby, H. S., Bek Craig, S. B., Thomsen, P. F., & Hansen, A. K. (2026). A new species of Lomechusoides (Coleoptera, Staphylinidae) from Formica polyctena anthills in Northeastern Europe. ZooKeys, 1275, 229–257. https://doi.org/10.3897/zookeys.1275.182781
Sørensen, E. F., Arvé, C., Gronlund, J. K., Melsvik, D., Pold, J. A., Knudsen, M., Thorsen, K., Aggerholm, A., & Ommen, H. B. (2026). Single-Cell Multi-Omics Identifies Measurable Residual Disease Targets Among Myelodysplasia- and Clonal Hematopoiesis-Related Genes in Acute Myeloid Leukemia. Cancers, 18(5), 787. https://doi.org/10.3390/cancers18050787
Federspiel Secher, C., Westmose Yde, C., Elmedal Laursen, B., Høgdall, E. l., Sylvain Thomsen, H., Svenstrup Poulsen, T., Sønderkær, M., Kringelbach, T., Malik Aagaard Jørgensen, M., Frydendahl Sick Olsen, R., Elaine Sørensen, A., Christian Baudet, Magnús Halldór Gíslason, Michael Knudsen, & Ida Kappel Buhl. (2026). Differences in tumor mutational burden assessment: a national ring trial. Acta Oncologica, 65, 178–180. https://doi.org/10.2340/1651-226x.2026.45220
Qvist, P., Mørch, N., Calderón, A., Kvamme, T., Donskov, J., Secher, D., Díaz-i-Calvete, J., Pediotidis-Maniatis, D., Zana, B., Durand, S., Rumi, B., Bjekic, J., Machizawa, M., Yamada, M., Ladefoged, L., Papoutsoglou, G., Ottosson, F., Bybjerg-Grauholm, J., Ernst, M., et al. (2026). Psychometric archetypes reveal biological signatures of vulnerability, resilience, and future mental health. https://doi.org/10.21203/rs.3.rs-8594362/v1
Qvist, P., Donskov, J., Deans, P., Høgfeldt, J., Borglum, A., Denham, M., & Brennand, K. (2026). BRD1 haploinsufficiency alters early neuronal programming and disrupts maturation in human induced glutamatergic neurons. https://doi.org/10.21203/rs.3.rs-8417267/v1
Rao, A. J., Knudsen, M. L., & Harrison, A. K. (2026). Erratum: What’s New in Shoulder and Elbow Surgery. Journal of Bone and Joint Surgery, 108(12), e13. https://doi.org/10.2106/jbjs.er2.25.00666
Rao, A. J., Knudsen, M. L., & Harrison, A. K. (2026). Erratum: What’s New in Shoulder and Elbow Surgery. Journal of Bone and Joint Surgery, 108(4), e6. https://doi.org/10.2106/jbjs.er.25.00666
Pedersen, B. M., Bergman, J., Pankratov, V., & Schierup, M. H. (2026). Ubiquitous impact of natural selection on nucleotide diversity in 178 species of primates. Genome Biology, 27(1). https://doi.org/10.1186/s13059-026-04093-z
Lee, H., Ko, K., Kim, S., Lee, G., Kim, S., Lee, J., Song, D.-Y., Bong, G., Han, J. H., Lee, J., Kim, Y. R., Lee, Y., Kim, E., Børglum, A. D., Grove, J., Kim, S. H., Sun, W., Yoo, H. J., & An, J.-Y. (2026). Co-occurrence of rare variants implicates gene pairs in cytoskeletal pathways and is associated with increased severity in autism spectrum disorder. Genome Biology, 27(1). https://doi.org/10.1186/s13059-026-04041-x
Sørensen, E. E., Frydendahl, A., Rasmussen, M. H., Nordentoft, I., Knudsen, M., Henriksen, T. V., Lindskrog, S. V., Dyrskjøt, L., Andersen, C. L., & Bramsen, J. B. (2026). Molecular residual disease assessment in colorectal and bladder cancer by somatic structural variant analysis of cell-free DNA whole-genome sequencing data. Journal of Translational Medicine, 24(1). https://doi.org/10.1186/s12967-026-07762-6
Dillon, M. R., Mastroianni, M. A., Frappa, N., Manzi, J., Luzzi, A. J., Alexander, F. J., Knudsen, M. L., Ablove, R. A., Trofa, D. P., & Ahmad, C. S. (2026). Factors Associated With Cumulative Shoulder and Elbow Injury Burden: A Retrospective Cohort Study of 1445 Major League Baseball Pitchers (2015-2025). Orthopaedic Journal of Sports Medicine, 14(6). https://doi.org/10.1177/23259671261445950
Mastroianni, M. A., Dillon, M. R., Obana, K. K., Morrissette, C. R., Frappa, N., Luzzi, A. J., Alexander, F. J., Knudsen, M. L., & Ahmad, C. S. (2026). Advanced Analytic and Pitch-Tracking Risk Factors for Capsulolabral Injuries in Major League Baseball Pitchers. Orthopaedic Journal of Sports Medicine, 14(4). https://doi.org/10.1177/23259671261425670
Afonso, L., Lagrotteria, A., Lavrador, A. S., Suarez‐Bregua, P., Álvarez‐González, M., Valente, R., Jensen, M. R., Saavedra, C., Morais, D. K., Sousa‐Pinto, I., Pierce, G. J., Magalhães, C., & Correia, A. M. (2026). Navigating Cetacean Mitochondrial Genome Data: Identifying Coverage and Deficiencies in Public Repositories. Molecular Ecology Resources, 26(3). Portico. https://doi.org/10.1111/1755-0998.70141
Gázquez-Gutiérrez, A., Chin, P., Peris, G., Gordon, K., Marchante, P. G., Witteveldt, J., Tristán-Ramos, P., Rouvière, J. O., Knol, L. I., Ivens, A., López-Onieva, L., Estévez, A. M., Garland, W., Jensen, T. H., Heras, S. R., & Macias, S. (2026). Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8. Nucleic Acids Research, 54(5). https://doi.org/10.1093/nar/gkag190
Kuhn, C. C., Chand, M. K., Todesca, S., Williams, K., Keidel, A., Garland, W., Jensen, T. H., & Conti, E. (2026). Direct coupling of the human nuclear exosome adaptors NEXT and PAXT with transcription termination and processing machineries. Nucleic Acids Research, 54(4). https://doi.org/10.1093/nar/gkag088
Rasmussen, A. M., Bouchard-Côté, A., & Pedersen, J. S. (2026). bayesReact: expression-coupled regulatory motif analysis detects microRNA activity across cancers, tissues, and at the single-cell level. Nucleic Acids Research, 54(4). https://doi.org/10.1093/nar/gkag072
Zampirolo, G., H. Ruter, A., Živaljević, I., Penezić, K., Thomsen, P. F., Orton, D., Grubin, M. K., Antić, N., & Pedersen, M. W. (2026). Ancient DNA reconstruction of Late Holocene ecosystems within the Carpathian Basin from paleo-meanders and archaeological deposits. Scientific Reports, 16(1). https://doi.org/10.1038/s41598-026-35509-2
Natividad Avila, M., Jung, S., Satterstrom, F. K., Fu, J. M., Levy, T., Sloofman, L. G., Klei, L., Pichardo, T., Marquez, D., Stevens, C. R., Cusick, C. M., Ames, J. L., Campos, G. S., Cerros, H., Chaskel, R., Costa, C. I. S., Cuccaro, M. L., Lopez, A. d. P., Fernandez, M., et al. (2026). Deleterious coding variation associated with autism is shared across ancestries. Nature Medicine, 32(4), 1519–1529. https://doi.org/10.1038/s41591-026-04228-6
Strom, N. I., Verhulst, B., Bacanu, S.-A., Cheesman, R., Purves, K. L., Gedik, H., Mitchell, B. L., Kwong, A. S., Faucon, A. B., Singh, K., Medland, S., Colodro-Conde, L., Krebs, K., Hoffmann, P., Herms, S., Gehlen, J., Ripke, S., Awasthi, S., Palviainen, T., et al. (2026). Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. Nature Genetics, 58(2), 275–288. https://doi.org/10.1038/s41588-025-02485-8
Skelton, M., Mitchell, B. L., Assary, E., Li, D., Morneau-Vaillancourt, G., Murphy, A. E., ter Kuile, A. R., Wang, R., Adams, M. J., Byrne, E. M., Corfield, E. C., Grimes, P. Z., Hannigan, L. J., Hu, J., Kõiv, K., Kwong, A. S. F., Papiol, S., Pettersen, J. H., Pistis, G., et al. (2026). Genome-wide meta-analysis of quantitatively measured generalized anxiety symptoms in individuals of European ancestry. Nature Human Behaviour. https://doi.org/10.1038/s41562-026-02476-7
Faergeman, S. L., Andreasen, L., Becher, N., Christiansen, M., Gravholt, C. H., Jensen, U. B., Jensen, J. M. B., Larsen, O. H., Markholt, S., Sandgaard, K. S., Vang, S., & Lildballe, D. L. (2026). Short-read genome sequencing at population scale: diagnostic insights from 2317 patients. European Journal of Human Genetics, 34(6), 769–776. https://doi.org/10.1038/s41431-026-02089-8
Thirstrup, J. P., Duan, J., Ribases Haro, M., Soler Artigas, M., Albiñana, C., Dalsgaard, S., Faraone, S. V., Werge, T., Bybjerg-Grauholm, J., Børglum, A. D., Agerbo, E., Yao, H., Chang, Z., Brikell, I., & Demontis, D. (2026). Common and rare variant contributions to discontinuation of stimulant treatment in ADHD. Translational Psychiatry, 16(1). https://doi.org/10.1038/s41398-026-03925-7
Nielsen, K. L., Lassen, J. K., M. Løber, I. M., Skovbo, F., Frisch, K., Czaja, T. P., Khakimov, B., Engelsen, S. B., Johannsen, M., & Villesen, P. (2026). Donor-Independent Metabolomics Enables Bloodstain Age Determination at Crime Scenes. Journal of Proteome Research. https://doi.org/10.1021/acs.jproteome.6c00199
Marquart Løber, I. M., Ward, L. J., Elmsjö, A., Söderberg, C., Villesen, P., Nielsen, K. L., & Green, H. (2026). Human-to-Rat Validation of PMI Biomarkers: A Bidirectional Cross-Species Metabolomics Study Reveals Asymmetric Translation. Analytical Chemistry, 98(20), 14883–14890. https://doi.org/10.1021/acs.analchem.6c00202
Obana, K. K., Weiss, D. L., Luzzi, A. J., LeVasseur, M. R., Knudsen, M. L., Jobin, C. M., & Levine, W. N. (2026). Reverse total shoulder arthroplasty is safe and effective in patients ≥90 Years old. JSES International, 10(1), 101374. https://doi.org/10.1016/j.jseint.2025.08.011
Czerwonka, N., Mastroianni, M. A., Hellwinkel, J. E., Malka, M., Kirkwood, G., Arvind, V., & Knudsen, M. L. (2026). Low glenoid vault bone density is a risk factor for failure of proximal humerus fracture fixation. Journal of Shoulder and Elbow Surgery, 35(5), 1185–1193. https://doi.org/10.1016/j.jse.2025.09.008
Goleva, S. B., Leu, C., Anne Feng, Y.-C., Burstein, D., Venkatesh, S., Birnbaum, R., Rajagopal, V. M., Straub, P., Christensen, J., Bautista, J. F., Busch, R. M., Najm, I. M., Grove, J., Børglum, A. D., Voloudakis, G., Roussos, P., Smoller, J., Lal, D., & Davis, L. K. (2026). Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients. Biological Psychiatry Global Open Science, 6(1), 100604. https://doi.org/10.1016/j.bpsgos.2025.100604
Villesen, P., Nielsen, K. L., & Frisch, K. (2026). Automated separation of overlapping fingermarks by non-negative matrix factorization of DESI mass spectrometry imaging data. Analytical and Bioanalytical Chemistry. https://doi.org/10.1007/s00216-026-06574-3
Pedersen, K., Green, K., Kristoffersen, E. L., Schinkel, T., Hansen, A. G., Palarasah, Y., Rovsing, A. B., Andersen, E. S., Valero, J., Civit, L., Laursen, N. S., Troldborg, A., Degn, S. E., & Thiel, S. (2026). Curbing Autoimmunity: A New Fab Fragment Targeting CD40‐CD40L Halts B‐Cell Activation and Differentiation. European Journal of Immunology, 56(2). Portico. https://doi.org/10.1002/eji.70158
Wootton, R. E., Crowley, J. J., Pol‐Fuster, J., Holmberg, A., Rück, C., Mataix‐Cols, D., & Fernández de la Cruz, L. (2026). Are There Causal Associations Between Obsessive‐Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi‐Directional Mendelian Randomization Study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 201(5), 321–330. Portico. https://doi.org/10.1002/ajmgb.70003
LaBianca, S., Lousdal, M. L., Dybdahl Krebs, M., Sahlholdt Hansen, O., Georgii Hellberg, K.-L., Lundberg, M., Østerby Sørensen, J., Gådin, J. R., Ohlsson, H., Grove, J., Børglum, A., Agerbo, E., Werge, T., Albiñana, C., Vilhjálmsson, B. J., Kendler, K. S., Plana-Ripoll, O., Schork, A. J., et al. (2026). Changes in Genetic Contributions to ASD and ADHD by Year of Diagnosis. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2026.1450
Vaez, M., Montalbano, S., Waples, R., Dybdahl Krebs, M., Georgii Hellberg, K.-L., Gådin, J., Stow, D., Holmans, P., van den Bree, M., Børglum, A. D., Helenius, D., Werge, T., Schork, A. J., Ingason, A., van den Bree, M. B. M., Kirov, G., Owen, M. J., Walters, J. T. R., et al. (2026). Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2026.1064

2025

(82 publications)

Donskov, J. G., Deans, P. M., Pediotidis-Maniatis, D., Høgfeldt, J. E., Børglum, A. D., Denham, M., Brennand, K. J., & Qvist, P. (2025). BRD1 haploinsufficiency alters early neuronal programming and disrupts maturation in human induced glutamatergic neurons. https://doi.org/10.64898/2025.12.19.695380
Nagy, I., Kristensen, P. S., Bornhofen, E., Malinowska, M., Nielsen, L. K., Schiemann, A., Rolund, N., Andersen, S. U., & Asp, T. (2025). Semi-automated image analysis of root architecture and early root development in faba bean and white clover and genomic estimation of breeding values and correlations. https://doi.org/10.64898/2025.12.01.691692
Kofod Petersen, A., Villesen, P., & Staun Larsen, L. (2025). The oral fingerprint: rapid 3D comparison of palatal rugae for forensic identification. Frontiers in Radiology, 5. https://doi.org/10.3389/fradi.2025.1638294
O’Connell, D., Kaiser-Bunbury, C., Aizpurua, O., Bechsgaard, J., Borregaard, M., Alberdi, A., Galetti, M., Gilbert, M., Gonçalves, F., Heinen, J., Jønsson, K., Ramos-Madrigal, J., Moyle, L., Pedersen, M., Schroeder, H., Simmons, B., Temeles, E., Thomsen, P., Vere, N. d., et al. (2025). Islands as laboratories of mutualistic interactions: integrating molecular approaches to advance to an eco-evolutionary understanding of mutualism. https://doi.org/10.22541/au.174860153.30868658/v1
Sørensen, E. F., Hellenthal, G., & Munch, K. (2025). Negative selection on baboon admixture is strongest on chromosome X. https://doi.org/10.21203/rs.3.rs-7456420/v1
Faergeman, S., Andreasen, L., Becher, N., Christiansen, M., Gravholt, C., Jensen, U., Jensen, J. M. B., Larsen, O., Markholt, S., Sandgaard, K., Vang, S., & Lildballe, D. (2025). Short-Read Genome Sequencing at Population Scale: Diagnostic Insights From 2,317 Patients. https://doi.org/10.21203/rs.3.rs-7432106/v1
Ollendorff, M., Chofflet, N., Bicer, D., Duan, J., Feller, B., Vilstrup, J., Groth, R., Sivagurunathan, S., Dashti, H., Pedersen, J. S., Werge, T., Borglum, A., Cimini, B., Jones, T. R., Claussnitzer, M., Madsen, P., Takahashi, H., Demontis, D., Thirup, S., … Skeldal, S. (2025). Rare missense variants of the leukocyte common antigen related receptor (LAR) display reduced activity in transcellular adhesion and synapse formation. https://doi.org/10.21203/rs.3.rs-5928514/v1
Rao, A. J., Knudsen, M. L., & Harrison, A. K. (2025). What’s New in Shoulder and Elbow Surgery. Journal of Bone and Joint Surgery. https://doi.org/10.2106/jbjs.25.00666
Lavrichenko, K., Engdal, E. S., Marvig, R. L., Jemt, A., Vignes, J. M., Almusa, H., Saether, K. B., Briem, E., Caceres, E., Elvarsdóttir, E. M., Gíslason, M. H., Haanpää, M. K., Henmyr, V., Hotakainen, R., Kaasinen, E., Kanninga, R., Khan, S., Lie-Nielsen, M. G., Madsen, M. B., et al. (2025). Recommendations for bioinformatics in clinical practice. Genome Medicine, 17(1). https://doi.org/10.1186/s13073-025-01543-4
Zhang, S.-J., Ma, J., Riera, M., Besenbacher, S., Niskanen, J. E., Salokorpi, N., Hundi, S., Hytönen, M. K., Zhou, T., Li, G.-M., Ostrander, E. A., Schierup, M. H., Lohi, H., & Wang, G.-D. (2025). Determinants of de novo mutations in extended pedigrees of 43 dog breeds. Genome Biology, 26(1). https://doi.org/10.1186/s13059-025-03804-2
Nørgaard, M., Rusan, M., Kondrup, K., Sørensen, E. M. G., Weiss, S., Bjerre, M. T., Fredsøe, J., Vang, S., Jensen, J. B., De Laere, B., Grönberg, H., Borre, M., Lindberg, J., & Sørensen, K. D. (2025). Deep targeted sequencing of circulating tumor DNA to inform treatment in patients with metastatic castration-resistant prostate cancer. Journal of Experimental & Clinical Cancer Research, 44(1). https://doi.org/10.1186/s13046-025-03356-0
Mastroianni, M. A., Kumar, P., Abdelaziz, A., Timoney, B. F., Luzzi, A. J., LeVasseur, M. R., Alexander, F. J., Knudsen, M. L., & Ahmad, C. S. (2025). The Impact of the Pitch Clock on UCL Surgery Rates and Performance in Major League Baseball Pitchers. Orthopaedic Journal of Sports Medicine, 13(10). https://doi.org/10.1177/23259671251374312
Balbuena, lloyd, Åhs, F., Peters, E., Mendes-Silva, A., & Speed, D. (2025). Does the Path From Cigarette Smoking to Suicide Death Go Through the Hospital? A Causal Mediation Analysis in a National Canadian Sample. Tobacco Use Insights, 18. https://doi.org/10.1177/1179173x251349612
Nazipi Bushi, S., Lund, M. B., Sandfeld, T., Nørskov, S. S., Fruergaard, S., Glasius, M., Bilde, T., & Schramm, A. (2025). A modified iChip for in situ cultivation of bacteria in arid environments. Applied and Environmental Microbiology. https://doi.org/10.1128/aem.01325-24
Hansen, M. M., Edwards, C., Grossen, C., Kardos, M., Laikre, L., & Ramakrishnan, U. (2025). Conservation Genomics—Making a Difference. Molecular Ecology, 34(23). Portico. https://doi.org/10.1111/mec.70191
Liu, Y.-z., Craig, S. B. B., Bechsgaard, J. S., Dicks, L. V., Bruun, H. H., Høye, T. T., Bilde, T., & Thomsen, P. F. (2025). Recent Demographic History Inferred From Allele Frequency Spectra: Evaluation by Simulations and Insights From Pool Sequencing of Wild Bees. Molecular Ecology, 35(1). Portico. https://doi.org/10.1111/mec.70169
Ho, T. A. T., Pedersen, J. B., Aagaard, A., Schou, M. F., Bechsgaard, J., Corcoran, D., Jørgensen, T. H., Normand, S., & Bilde, T. (2025). Gene Flow Disruption and Population Declines in a Soil Arthropod in Fragmented Habitats. Molecular Ecology. Portico. https://doi.org/10.1111/mec.17820
Dallaire, X., Normandeau, E., Brazier, T., Harris, L., Hansen, M. M., Mérot, C., & Moore, J. (2025). Leveraging Whole Genomes, Mitochondrial DNA and Haploblocks to Decipher Complex Demographic Histories: An Example From a Broadly Admixed Arctic Fish. Molecular Ecology, 34(10). Portico. https://doi.org/10.1111/mec.17772
Tengstedt, A. N. B., Liu, S., Jacobsen, M. W., Ulmo‐Diaz, G., Jónsson, B., Pujolar, J. M., & Hansen, M. M. (2025). Genomic Footprints of Hybridisation in North Atlantic Eels (Anguilla anguilla and A. rostrata). Molecular Ecology. Portico. https://doi.org/10.1111/mec.17664
Balding, D. J., & Speed, D. (2025). Recent Statistical Innovations in Human Genetics. Annals of Human Genetics, 89(5), 241–254. Portico. https://doi.org/10.1111/ahg.12606
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Johansen, N. H., Bellucci, A., Hansen, P. B., Marum, P., Amdahl, H., Gylstrøm, K. H., Rognli, O. A., Kemešytė, V., Brazauskas, G., Greve, M., Persson, C., Isolahti, M., Helgadóttir, Á., Aavola, R., Asp, T., & Ramstein, G. P. (2025). Genomic prediction of agronomic traits in perennial ryegrass (Lolium perenne L.) and genotype x environment interactions at the limit of the species distribution. Theoretical and Applied Genetics, 138(11). https://doi.org/10.1007/s00122-025-05064-x
Kretsch, R. C., Albrecht, R., Andersen, E. S., Chen, H., Chiu, W., Das, R., Gezelle, J. G., Hartmann, M. D., Höbartner, C., Hu, Y., Jadhav, S., Johnson, P. E., Jones, C. P., Koirala, D., Kristoffersen, E. L., Largy, E., Lewicka, A., Mackereth, C. D., Marcia, M., … Kryshtafovych, A. (2025). Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers. Proteins: Structure, Function, and Bioinformatics. Portico. https://doi.org/10.1002/prot.70043
Liu, S., Jonsson, B., Greenberg, L., & Hansen, M. M. (2025). Stronger Parental Than Temperature Effects on Methylation in Juvenile Brown Trout (Salmo trutta). Ecology and Evolution, 15(9). Portico. https://doi.org/10.1002/ece3.72154
Nielsen, T. T., Bali, P., Grove, J., Mohr-Jensen, C., Werge, T., Dalsgaard, S., Børglum, A. D., Sonuga-Barke, E., Minnis, H., Demontis, D., Corfield, E. C., Tbartz van Elst, L., Mattheisen, M., de Wit, M. M., Uddin, M. J., Anney, R. J. L., Scherer, S. W., Bourgeron, T., & Polderman, T. J. C. (2025). Genetic Architecture and Risk of Childhood Maltreatment Across 5 Psychiatric Diagnoses. JAMA Psychiatry, 82(8), 790. https://doi.org/10.1001/jamapsychiatry.2025.0828

2024

(74 publications)

Okholm, T. L. H., Kamstrup, A. B., Nielsen, M. M., Hollensen, A. K., Graversgaard, M. L., Sørensen, M. H., Kristensen, L. S., Vang, S., Park, S. S., Yeo, E., Dyrskjøt, L., Kjems, J., Pedersen, J. S., & Damgaard, C. K. (2024). circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA. ELife, 13. CLOCKSS. https://doi.org/10.7554/elife.91783
Luzzi, A. J., Czerwonka, N., Rogalski, B., Knudsen, M. L., & Levine, W. N. (2024). “Trend” Statement Use in the Orthopaedic Literature. Journal of the American Academy of Orthopaedic Surgeons. https://doi.org/10.5435/jaaos-d-23-00770
Lin, Y., Rasmussen, M. H., Christensen, M. H., Frydendahl, A., Maretty, L., Andersen, C. L., & Besenbacher, S. (2024). Evaluating Bioinformatics Processing of Somatic Variant Detection in cfDNA Using Targeted Sequencing with UMIs. International Journal of Molecular Sciences, 25(21), 11439. https://doi.org/10.3390/ijms252111439
Frydendahl, A., Rasmussen, M. H., Jensen, S. Ø., Henriksen, T. V., Demuth, C., Diekema, M., Ditzel, H. J., Wen, S. W. C., Pedersen, J. S., Dyrskjøt, L., & Andersen, C. L. (2024). Error-Corrected Deep Targeted Sequencing of Circulating Cell-Free DNA from Colorectal Cancer Patients for Sensitive Detection of Circulating Tumor DNA. International Journal of Molecular Sciences, 25(8), 4252. https://doi.org/10.3390/ijms25084252
Griffiths, A. G., Fechete, L. I., Larking, A., Heslop, A., Hannaford, R., Anderson, C., Hong, W., Prakash, S., Mace, W., Alikhani, S., Hofmann, R., Tausen, M., Schierup, M. H., & Andersen, S. U. (2024). Harnessing cold adaptation for post-glacial colonisation: galactinol synthase expression and raffinose accumulation in a polyploid and its progenitors. https://doi.org/10.22541/au.171261364.45839041/v1
Malinowska, M., Kristensen, P. S., Nielsen, B., Fè, D., Ruud, A. K., Lenk, I., Greve, M., & Asp, T. (2024). The Value of Early Root Development Traits in Breeding Programs for Biomass Yield in Perennial Ryegrass (Lolium perenne L.). https://doi.org/10.21203/rs.3.rs-5197858/v1
Villesen, P., Lassen, J., Nielsen, K., Hindhede, L., Mikkelsen, S., Kjerulff, B., Ostrowski, S., Sørensen, E., Mikkelsen, C., Pedersen, O., Bruun, M. T., Aagaard, B., Johannsen, M., & Erikstrup, C. (2024). Longitudinal pre-diagnostic samples allow early osteoporosis diagnosis. https://doi.org/10.21203/rs.3.rs-4642034/v1
Petersen, L., Christiansen, G., Chatwin, H., Yilmaz, Z., Schendel, D., Bulik, C., Grove, J., Brikell, I., Semark, B., Holde, K., Abdulkadir, M., Hubel, C., Albiñana, C., Vilhjálmsson, B., Borglum, A., Demontis, D., Mortensen, P., & Larsen, J. (2024). The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder. https://doi.org/10.21203/rs.3.rs-4236554/v1
Koellinger, P. D., Kweon, H., Burik, C., Ning, Y., Ahlskog, R., Xia, C., Abner, E., Bao, Y., Bhatta, L., Faquih, T., de Feijter, M., Fisher, P., Gelemanović, A., Giannelis, A., Hottenga, J.-J., Khalili, B., Lee, Y., Li-Gao, R., Masso, J., … Benjamin, D. (2024). Associations between common genetic variants and income provide insights about the socioeconomic health gradient. https://doi.org/10.21203/rs.3.rs-3782300/v1
Luzzi, A., Boddapati, V., Rogalski, B. L., Knudsen, M. L., Levine, W. N., & Jobin, C. M. (2024). Graft Resorption After Posterior Distal Tibial Allograft Augmentation for Posterior Shoulder Instability. JBJS Case Connector, 14(1). https://doi.org/10.2106/jbjs.cc.23.00511
Zhang, J., Weissenkampen, J. D., Kember, R. L., Hougaard, D. M., Bybjerg-Grauholm, J., Werge, T., Als, T. D., Rosengren, A., Grove, J., Børglum, A. D., Robinson, E. B., Brodkin, E. S., Almasy, L., Bucan, M., & Sebro, R. (2024). Phenotypic and ancestry-related assortative mating in autism. Molecular Autism, 15(1). https://doi.org/10.1186/s13229-024-00605-5
Kim, S.-W., Lee, H., Song, D. Y., Lee, G.-H., Ji, J., Park, J. W., Han, J. H., Lee, J. W., Byun, H. J., Son, J. H., Kim, Y. R., Lee, Y., Kim, J., Jung, A., Lee, J., Kim, E., Kim, S. H., Lee, J. H., Satterstrom, F. K., … An, J.-Y. (2024). Whole genome sequencing analysis identifies sex differences of familial pattern contributing to phenotypic diversity in autism. Genome Medicine, 16(1). https://doi.org/10.1186/s13073-024-01385-6
Balle, C. M., Kassentoft, C. G., van Heusden, J. I., Knudsen, M., Raaby, L., & Gravholt, C. H. (2024). Rare Case of a Turner Syndrome Patient with Metastatic Dysgerminoma and No Y-Chromosomal Material with Pathogenic Variants Found in <i>KIT</i> and <i>MTOR</i> Sexual Development, 1–8. Portico. https://doi.org/10.1159/000536236
Daskalakis, N. P., Iatrou, A., Chatzinakos, C., Jajoo, A., Snijders, C., Wylie, D., DiPietro, C. P., Tsatsani, I., Chen, C.-Y., Pernia, C. D., Soliva-Estruch, M., Arasappan, D., Bharadwaj, R. A., Collado-Torres, L., Wuchty, S., Alvarez, V. E., Dammer, E. B., Deep-Soboslay, A., … Duong, D. M. (2024). Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science, 384(6698). https://doi.org/10.1126/science.adh3707
Vallina, N. S., McRae, E. K. S., Geary, C., & Andersen, E. S. (2024). An RNA origami robot that traps and releases a fluorescent aptamer. Science Advances, 10(12). https://doi.org/10.1126/sciadv.adk1250
Fechete, L. I., Larking, A. C., Heslop, A., Hannaford, R., Anderson, C. B., Hong, W., Prakash, S., Mace, W., Alikhani, S., Hofmann, R. W., Tausen, M., Schierup, M. H., Andersen, S. U., & Griffiths, A. G. (2024). Harnessing cold adaptation for postglacial colonisation: Galactinol synthase expression and raffinose accumulation in a polyploid and its progenitors. Plant, Cell & Environment. Portico. https://doi.org/10.1111/pce.15009
Tengstedt, A. N. B., Liu, S., Jacobsen, M. W., Gundlund, C., Møller, P. R., Berg, S., Bekkevold, D., & Hansen, M. M. (2024). Genomic insights on conservation priorities for North Sea houting and European lake whitefish (Coregonus spp.). Molecular Ecology. Portico. https://doi.org/10.1111/mec.17367
Cádiz, M. I., Tengstedt, A. N. B., Sørensen, I. H., Pedersen, E. S., Fox, A. D., & Hansen, M. M. (2024). Demographic History and Inbreeding in Two Declining Sea Duck Species Inferred From Whole‐Genome Sequence Data. Evolutionary Applications, 17(9). Portico. https://doi.org/10.1111/eva.70008
Thomassen, E. E., Sigsgaard, E. E., Jensen, M. R., Olsen, K., Hansen, M. D. D., & Thomsen, P. F. (2024). Environmental DNA metabarcoding reveals temporal dynamics but functional stability of arthropod communities in cattle dung. Journal of Animal Ecology. Portico. https://doi.org/10.1111/1365-2656.14119
Sørensen, E. F., Hellenthal, G., & Munch, K. (2024). Negative selection on baboon admixture is strongest on chromosome X. https://doi.org/10.1101/2024.12.18.629079
Lin, Y., Oroperv, C., Porsgård, P. S., Frydendahl Boll Johansen, A., Rasmussen, M. H., Bataillon, T., Schierup, M. H., Andersen, C. L., Almstrup, K., & Besenbacher, S. (2024). Accurate calling of low-frequency somatic mutations by sample-specific modeling of error rates. https://doi.org/10.1101/2024.12.17.629019
Olsen, L. R., Odinokov, D., Holsting, J. Q., Kondrup, K., Iisager, L., Rusan, M., Buus, S., Laursen, B. E., Borre, M., Jochumsen, M. R., Bouchelouche, K., Frydendahl, A., Rasmussen, M. H., Henriksen, T. V., Nesic, M., Demuth, C., Lindskrog, S. V., Nordentoft, I., Lamy, P., … Besenbacher, S. (2024). Cross-dataset pan-cancer detection: Correlating cell-free DNA fragment coverage with open chromatin sites across cell types. https://doi.org/10.1101/2024.11.26.24317971
Lavrichenko, K., Engdal, E. S., Marvig, R. L., Jemt, A., Vignes, J. M., Almusa, H., Saether, K. B., Briem, E., Caceres, E., Elvarsdóttir, E. M., Gíslason, M. H., Haanpää, M. K., Henmyr, V., Hotakainen, R., Kaasinen, E., Kanninga, R., Khan, S., Lie-Nielsen, M. G., Madsen, M. B., … Bagger, F. O. (2024). Recommendations for Bioinformatics in Clinical Practice. https://doi.org/10.1101/2024.11.23.624993
Zhang, C., Reid, K., Schierup, M. H., Wang, H., Candolin, U., & Merilä, J. (2024). Rate ofde novomutations in the three-spined stickleback. https://doi.org/10.1101/2024.11.13.623523
Okewole, A., Bourque, V.-R., Koko, M., Huguet, G., Borglum, A. D., Grove, J., Jacquemont, S., Baron-Cohen, S., & Warrier, V. (2024). Common genetic variants are associated with increased likelihood of some co-occurring mental health conditions among autistic individuals. https://doi.org/10.1101/2024.11.11.24317097
Vaez, M., Montalbano, S., Waples, R., Krebs, M. D., Hellberg, K.-L. G., Gådin, J., Bybjerg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Nordentoft, M., Geschwind, D. H., Helenius, D., Werge, T., Schork, A. J., & Ingason, A. (2024). Evaluating the Joint Effects of Recurrent Copy Number Variants and Polygenic Scores on the Risk of Psychiatric Disorders in the iPSYCH2015 Case-Cohort Sample. https://doi.org/10.1101/2024.09.23.24314234
Rasmussen, A. M., Bouchard-Cote, A., & Pedersen, J. S. (2024). bayesReact: Expression-coupled regulatory motif analysis detects microRNA activity in cancer and at the single cell level. https://doi.org/10.1101/2024.09.10.612047
Mørch, N., Calderón, A. B., Kvamme, T. L., Donskov, J. G., Zana, B., Durand, S., Bjekic, J., Machizawa, M. G., Yamada, M., Ottosson, F. A., Bybjerg-Grauholm, J., Ernst, M., Børglum, A. D., Sandberg, K., & Qvist, P. (2024). Identification of multimodal mental health signatures in the young population using deep phenotyping. https://doi.org/10.1101/2024.09.01.24312906
Zhang, X., Grove, J., Gu, Y., Buus, C. K., Nielsen, L. K., Neufeld, S. A. S., Koko, M., Malawsky, D. S., Wade, E., Verhoef, E., Gui, A., Hegemann, L., Geschwind, D. H., Wray, N. R., Havdahl, A., Ronald, A., … Warrier, V. (2024). An axis of genetic heterogeneity in autism is indexed by age at diagnosis and is associated with varying developmental and mental health profiles. https://doi.org/10.1101/2024.07.31.24311279
Hof, J. P., & Speed, D. (2024). LDAK-KVIK performs fast and powerful mixed-model association analysis of quantitative and binary phenotypes. https://doi.org/10.1101/2024.07.25.24311005
Porsborg, P. S., Charmouh, A. P., Singh, V. K., Winge, S. B., Hvilsom, C., Pelizzola, M., Laurentino, S., Neuhaus, N., Hobolth, A., Bataillon, T., Almstrup, K., Besenbacher, S., & Schierup, M. H. (2024). Insights into gene conversion and crossing-over processes from long-read sequencing of human, chimpanzee and gorilla testes and sperm. https://doi.org/10.1101/2024.07.05.601967
Charmouh, A. P., Sørud, P. P., Hansen, L. T., Besenbacher, S., Winge, S. B., Almstrup, K., Hobolth, A., Bataillon, T., & Schierup, M. H. (2024). Estimating gene conversion tract length and rate from PacBio HiFi data. https://doi.org/10.1101/2024.07.05.601865
Strom, N. I., Verhulst, B., Bacanu, S.-A., Cheesman, R., Purves, K. L., Gedik, H., Mitchell, B. L., Kwong, A. S., Faucon, A. B., Singh, K., Medland, S., Colodro-Conde, L., Krebs, K., Hoffmann, P., Herms, S., Gehlen, J., Ripke, S., Awasthi, S., … Palviainen, T. (2024). Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. https://doi.org/10.1101/2024.07.03.24309466
Zhang, S.-J., Ma, J., Riera, M., Besenbacher, S., Niskanen, J., Salokorpi, N., Hundi, S., Hytönen, M. K., Zhou, T., Li, G.-M., Ostrander, E. A., Schierup, M. H., Lohi, H., & Wang, G.-D. (2024). Determinants of de novo mutations in extended pedigrees of 43 dog breeds. https://doi.org/10.1101/2024.06.04.596747
Fisher, D. N., Bechsgaard, J., & Bilde, T. (2024). Exploring changes in social spider DNA methylation profiles when succumbing to infection in CpG, CHG, and CHH contexts. https://doi.org/10.1101/2024.05.21.595160
Ma, J., Bechsgaard, J., Aagaard, A., Villesen, P., Bilde, T., & Schierup, M. (2024). Sociality in spiders is an evolutionary dead-end. https://doi.org/10.1101/2024.04.22.590577
Gu, Y., Maria-Stauffer, E., Bedford, S. A., Romero-Garcia, R., Grove, J., Børglum, A. D., Martin, H., Baron-Cohen, S., Bethlehem, R. A. I., & Warrier, V. (2024). Polygenic scores for autism are associated with neurite density in adults and children from the general population. https://doi.org/10.1101/2024.04.10.24305539
Smith, A. G., Malinowska, M., Janss, L., Ruud, A. K., Krusell, L., Jensen, J. D., & Asp, T. (2024). Automated Seminal Root Angle Measurement with Corrective Annotation. https://doi.org/10.1101/2024.03.13.584803
Strom, N. I., Gerring, Z. F., Galimberti, M., Yu, D., Halvorsen, M. W., Abdellaoui, A., Rodriguez-Fontenla, C., Sealock, J. M., Bigdeli, T., Coleman, J. R., Mahjani, B., Thorp, J. G., Bey, K., Burton, C. L., Luykx, J. J., Zai, G., Alemany, S., Andre, C., … Askland, K. D. (2024). Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci. https://doi.org/10.1101/2024.03.13.24304161
Strom, N. I., Halvorsen, M. W., Tian, C., Rück, C., Kvale, G., Hansen, B., Bybjerg-Grauholm, J., Grove, J., Boberg, J., Becker Nissen, J., Damm Als, T., Werge, T., de Schipper, E., Fundin, B., Hultman, C., Höffler, K. D., Pedersen, N., Sandin, S., … Bulik, C. (2024). Genome-wide association study identifies new loci associated with OCD. https://doi.org/10.1101/2024.03.06.24303776
Nielsen, T. T., Duan, J., Levey, D. F., Bragi Walters, G., Johnson, E. C., Thorgeirsson, T., Werge, T., Mortensen, P. B., Stefansson, H., Stefansson, K., Hougaard, D. M., Agrawal, A., Gelernter, J., Grove, J., Børglum, A. D., & Demontis, D. (2024). Disentangling the shared genetics of ADHD, cannabis use disorder and cannabis use and prediction of cannabis use disorder in ADHD. https://doi.org/10.1101/2024.02.22.24303124
Tabrizi, F., Rosén, J., Grönvall, H., William-Olsson, V. R., Arner, E., Magnusson, P. K., Palm, C., Larsson, H., Viktorin, A., Bernhardsson, J., Björkdahl, J., Jansson, B., Sundin, Ö., Zhou, X., Speed, D., & Åhs, F. (2024). Heritability and polygenic load for combined anxiety and depression. https://doi.org/10.1101/2024.01.31.24302045
Kweon, H., Burik, C. A. P., Ning, Y., Ahlskog, R., Xia, C., Abner, E., Bao, Y., Bhatta, L., Faquih, T. O., de Feijter, M., Fisher, P., Gelemanović, A., Giannelis, A., Hottenga, J.-J., Khalili, B., Lee, Y., Li-Gao, R., Masso, J., Myhre, R., … Koellinger, P. D. (2024). Associations between common genetic variants and income provide insights about the socioeconomic health gradient. https://doi.org/10.1101/2024.01.09.574865
Martínez Villar, M., Bechsgaard, J., Bilde, T., Albo, M. J., & Tomasco, I. H. (2024). Impact of pre-copulatory sexual cannibalism on genetic diversity and efficacy of selection. Biology Letters, 20(5). https://doi.org/10.1098/rsbl.2023.0505
Breinbjerg, A., Jørgensen, C. S., Walters, G. B., Grove, J., Als, T. D., Kamperis, K., Stéfansdóttir, L., Thirstrup, J. P., Borg, B., Albiñana, C., Vilhjálmsson, B. J., Eðvarðsson, V. Ö., Stefánsson, H., Mortensen, P. B., Agerbo, E., Werge, T., Børglum, A., Demontis, D., Stefánsson, K., … Christensen, J. H. (2024). Exploring the Genetic Risk of Childhood Daytime Urinary Incontinence: A Genome-Wide Association Study. Journal of Urology, 212(6), 851–861. https://doi.org/10.1097/ju.0000000000004187
Ho, T. A. T., Downing, P. A., Schou, M. F., Bechsgaard, J., Thomsen, P. F., Jorgensen, T. H., & Bilde, T. (2024). The relationship between neutral genetic diversity and performance in wild arthropod populations. Journal of Evolutionary Biology, 37(10), 1170–1180. https://doi.org/10.1093/jeb/voae099
Malham, M., Vestergaard, M. V., Bataillon, T., Villesen, P., Dempfle, A., Bang, C., Engsbro, A. L., Jakobsen, C., Franke, A., Wewer, V., Thingholm, L. B., & Petersen, A. M. (2024). The Composition of the Fecal and Mucosa-adherent Microbiota Varies Based on Age and Disease Activity in Ulcerative Colitis. Inflammatory Bowel Diseases. https://doi.org/10.1093/ibd/izae179
Aagaard, A., Bechsgaard, J., Sørensen, J. G., Sandfeld, T., Settepani, V., Bird, T. L., Lund, M. B., Malmos, K. G., Falck-Rasmussen, K., Darolti, I., Nielsen, K. L., Johannsen, M., Vosegaard, T., Tregenza, T., Verhoeven, K. J. F., Mank, J. E., Schramm, A., & Bilde, T. (2024). Molecular Mechanisms of Temperature Tolerance Plasticity in an Arthropod. Genome Biology and Evolution, 16(8). https://doi.org/10.1093/gbe/evae165
Schoen, D. J., & Speed, D. (2024). The heritability of fitness in a wild annual plant population with hierarchical size structure. Evolution, 78(10), 1739–1745. https://doi.org/10.1093/evolut/qpae112
Smith, A. G., Malinowska, M., Ruud, A. K., Janss, L., Krusell, L., Jensen, J. D., & Asp, T. (2024). Automated seminal root angle measurement with corrective annotation. AoB PLANTS, 16(5). https://doi.org/10.1093/aobpla/plae046
McRae, E. K. S., Wan, C. J. K., Kristoffersen, E. L., Hansen, K., Gianni, E., Gallego, I., Curran, J. F., Attwater, J., Holliger, P., & Andersen, E. S. (2024). Cryo-EM structure and functional landscape of an RNA polymerase ribozyme. Proceedings of the National Academy of Sciences, 121(3). https://doi.org/10.1073/pnas.2313332121
Bergstedt, J., Pasman, J. A., Ma, Z., Harder, A., Yao, S., Parker, N., Treur, J. L., Smit, D. J. A., Frei, O., Shadrin, A. A., Meijsen, J. J., Shen, Q., Hägg, S., Tornvall, P., Buil, A., Werge, T., Hjerling-Leffler, J., Als, T. D., Børglum, A. D., … Fang, F. (2024). Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease. Nature Cardiovascular Research, 3(6), 754–769. https://doi.org/10.1038/s44161-024-00488-y
Kofod Petersen, A., Forgie, A., Bindslev, D. A., Villesen, P., & Staun Larsen, L. (2024). Automatic removal of soft tissue from 3D dental photo scans; an important step in automating future forensic odontology identification. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-63198-2
Paina, C., Fois, M., Asp, T., Jensen, J., Hansen, P. B., & Rohde, P. D. (2024). The soil microbiome of Lolium perenne L. depends on host genotype, is modified by nitrogen level and varies across season. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-56353-2
Zheng, S. L., Henry, A., Cannie, D., Lee, M., Miller, D., McGurk, K. A., Bond, I., Xu, X., Issa, H., Francis, C., De Marvao, A., Theotokis, P. I., Buchan, R. J., Speed, D., Abner, E., Adams, L., Aragam, K. G., Ärnlöv, J., Raja, A. A., … Lumbers, R. T. (2024). Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy. Nature Genetics, 56(12), 2646–2658. https://doi.org/10.1038/s41588-024-01952-y
Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babić, D., … Bacanu, S.-A. (2024). Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nature Genetics, 56(5), 792–808. https://doi.org/10.1038/s41588-024-01707-9
Voloudakis, G., Therrien, K., Tomasi, S., Rajagopal, V. M., Choi, S. W., Demontis, D., Fullard, J. F., Børglum, A. D., O’Reilly, P. F., Hoffman, G. E., & Roussos, P. (2024). Neuropsychiatric polygenic scores are weak predictors of professional categories. Nature Human Behaviour. https://doi.org/10.1038/s41562-024-02074-5
Montalbano, S., Krebs, M. D., Rosengren, A., Vaez, M., Hellberg, K.-L. G., Mortensen, P. B., Børglum, A. D., Geschwind, D. H., Hougaard, D. M., Nordentoft, M., Mors, O., Grove, J., Als, T. D., Buil, A., Schork, A. J., Gådin, J., Zetterberg, R., Appadurai, V., … Ingason, A. (2024). Analysis of exonic deletions in a large population study provides novel insights into NRXN1 pathology. Npj Genomic Medicine, 9(1). https://doi.org/10.1038/s41525-024-00450-8
Trastulla, L., Dolgalev, G., Moser, S., Jiménez-Barrón, L. T., Andlauer, T. F. M., von Scheidt, M., Ruderfer, D. M., Ripke, S., McQuillin, A., Stahl, E. A., Domenici, E., Adolfsson, R., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., … Ziller, M. J. (2024). Distinct genetic liability profiles define clinically relevant patient strata across common diseases. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-49338-2
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., … McGrath, J. J. (2024). Publisher Correction: Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46199-7
Fisher, D. N., Bechsgaard, J., & Bilde, T. (2024). Exploring changes in social spider DNA methylation profiles in all cytosine contexts following infection. Heredity, 133(6), 410–417. https://doi.org/10.1038/s41437-024-00724-y
Christiansen, G. B., Petersen, L. V., Chatwin, H., Yilmaz, Z., Schendel, D., Bulik, C. M., Grove, J., Brikell, I., Semark, B. D., Holde, K., Abdulkadir, M., Hübel, C., Albiñana, C., Vilhjálmsson, B. J., Børglum, A. D., Demontis, D., Mortensen, P. B., & Larsen, J. T. (2024). The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder. Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02825-w
Mundy, J., Hall, A. S. M., Steinbach, J., Albinaña, C., Agerbo, E., Als, T. D., Thapar, A., McGrath, J. J., Vilhjálmsson, B. J., Nordentoft, M., Werge, T., Børglum, A., Mortensen, P. B., & Musliner, K. L. (2024). Polygenic liabilities and treatment trajectories in early-onset depression: a Danish register-based study. Psychological Medicine, 54(14), 3828–3837. https://doi.org/10.1017/s0033291724002186
Wimberley, T., Brikell, I., Astrup, A., Larsen, J. T., Petersen, L. V., Albiñana, C., Vilhjálmsson, B. J., Bulik, C. M., Chang, Z., Fanelli, G., Bralten, J., Mota, N. R., Salas-Salvadó, J., Fernandez-Aranda, F., Bulló, M., Franke, B., Børglum, A., Mortensen, P. B., Horsdal, H. T., & Dalsgaard, S. (2024). Shared familial risk for type 2 diabetes mellitus and psychiatric disorders: a nationwide multigenerational genetics study. Psychological Medicine, 1–10. https://doi.org/10.1017/s0033291724001053
Loeschcke, V., & Schierup, M. H. (2024). Biographical sketch: Freddy Bugge Christiansen. Theoretical Population Biology, 156, 130. https://doi.org/10.1016/j.tpb.2024.02.006
Pisanu, C., Congiu, D., Meloni, A., Paribello, P., Severino, G., Ardau, R., Chillotti, C., Als, T. D., Børglum, A. D., Del Zompo, M., Manchia, M., & Squassina, A. (2024). Sex differences in shared genetic determinants between severe mental disorders and metabolic traits. Psychiatry Research, 342, 116195. https://doi.org/10.1016/j.psychres.2024.116195
Nordentoft, I., Lindskrog, S. V., Birkenkamp-Demtröder, K., Gonzalez, S., Kuzman, M., Levatic, J., Glavas, D., Ptashkin, R., Smadbeck, J., Afterman, D., Lauterman, T., Cohen, Y., Donenhirsh, Z., Tavassoly, I., Alon, U., Frydendahl, A., Rasmussen, M. H., Andersen, C. L., Lamy, P., … Dyrskjøt, L. (2024). Whole-genome Mutational Analysis for Tumor-informed Detection of Circulating Tumor DNA in Patients with Urothelial Carcinoma. European Urology. https://doi.org/10.1016/j.eururo.2024.05.014
Thomsen, P. F., Jensen, M. R., & Sigsgaard, E. E. (2024). A vision for global eDNA-based monitoring in a changing world. Cell. https://doi.org/10.1016/j.cell.2024.04.019
Strom, N. I., Halvorsen, M. W., Grove, J., Ásbjörnsdóttir, B., Luðvígsson, P., Thorarensen, Ó., de Schipper, E., Bäckmann, J., Andrén, P., Tian, C., Yu, D., Sul, J. H., Tsetsos, F., Nawaz, M. S., Huang, A. Y., Zelaya, I., Illmann, C., Osiecki, L., Darrow, S. M., … Mattheisen, M. (2024). Genome-Wide Association Study Meta-Analysis of 9619 Cases With Tic Disorders. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2024.07.025
Speed, D., & Evans, D. M. (2024). Estimating disease heritability from complex pedigrees allowing for ascertainment and covariates. The American Journal of Human Genetics, 111(4), 680–690. https://doi.org/10.1016/j.ajhg.2024.02.010
Weiss, S., Lamy, P., Rusan, M., Nørgaard, M., Ulhøi, B. P., Knudsen, M., Kassentoft, C. G., Farajzadeh, L., Jensen, J. B., Pedersen, J. S., Borre, M., & Sørensen, K. D. (2024). Exploring the tumor genomic landscape of aggressive prostate cancer by whole‐genome sequencing of tissue or liquid biopsies. International Journal of Cancer, 155(2), 298–313. Portico. https://doi.org/10.1002/ijc.34949
Jensen, M. R., Agersnap, S., Sigsgaard, E. E., Ávila, M. de P., Glenner, H., Wisz, M. S., & Thomsen, P. F. (2024). The Core of the Matter—Importance of Identification Method and Biological Replication for Benthic Marine Monitoring. Ecology and Evolution, 14(11). Portico. https://doi.org/10.1002/ece3.70556
Andersen, L., Christensen, D. S., Kjær, A., Knudsen, M., Andersen, A. K., Laursen, M. B., Ahrenfeldt, J., Laursen, B. E., & Birkbak, N. J. (2024). Exploring the molecular landscape of cancer of unknown primary: A comparative analysis with other metastatic cancers. Molecular Oncology. Portico. https://doi.org/10.1002/1878-0261.13664
Vaez, M., Montalbano, S., Calle Sánchez, X., Georgii Hellberg, K.-L., Dehkordi, S. R., Krebs, M. D., Meijsen, J., Shorter, J., Bybjerg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Helenius, D., Raznahan, A., Thompson, W. K., … Bækvad-Hansen, M. (2024). Population-Based Risk of Psychiatric Disorders Associated With Recurrent Copy Number Variants. JAMA Psychiatry, 81(10), 957. https://doi.org/10.1001/jamapsychiatry.2024.1453

2023

(100 publications)

Sørensen, S. G., Shrikhande, A., Poulsgaard, G. A., Christensen, M. H., Bertl, J., Laursen, B. E., Hoffmann, E. R., & Pedersen, J. S. (2023). Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns. ELife, 12. CLOCKSS. https://doi.org/10.7554/elife.81224
Kjeldbjerg Lassen, J., Bradshaw, R., Villesen, P., & Francese, S. (2023). Statistical Modelling Investigation of MALDI-MSI-Based Approaches for Document Examination. Molecules, 28(13), 5207. https://doi.org/10.3390/molecules28135207
Rasmussen, M. Q., Tindbæk, G., Nielsen, M. M., Merrild, C., Steiniche, T., Pedersen, J. S., Moestrup, S. K., Degn, S. E., & Madsen, M. (2023). Epigenetic Silencing of LRP2 Is Associated with Dedifferentiation and Poor Survival in Multiple Solid Tumor Types. Cancers, 15(6), 1830. https://doi.org/10.3390/cancers15061830
Forte, F. P., Malinowska, M., Nagy, I., Schmid, J., Dijkwel, P., Hume, D. E., Johnson, R. D., Simpson, W. R., & Asp, T. (2023). Corrigendum: Methylome changes in Lolium perenne associated with long-term colonisation by the endophytic fungus Epichloë sp. LpTG-3 strain AR37. Frontiers in Plant Science, 14. https://doi.org/10.3389/fpls.2023.1332690
Forte, F. P., Malinowska, M., Nagy, I., Schmid, J., Dijkwel, P., Hume, D. E., Johnson, R. D., Simpson, W. R., & Asp, T. (2023). Methylome changes in Lolium perenne associated with long-term colonisation by the endophytic fungus Epichloë sp. LpTG-3 strain AR37. Frontiers in Plant Science, 14. https://doi.org/10.3389/fpls.2023.1258100
Bonte, D., Rose, C., Bastiaensen, T., Bechsgaard, J. J., Bilde, T., Dahirel, M., Wolf, K. D., Thylys, H., Uytterschaut, T., & Vanthournout, B. (2023). Urbanization impacts short- but not long-distance natal dispersal in a common orb web spider. https://doi.org/10.22541/au.168734169.94419088/v1
Nielsen, S. V., Vaughn, A. H., Leppälä, K., Landis, M. J., Mailund, T., & Nielsen, R. (2023). Bayesian inference of admixture graphs on Native American and Arctic populations. PLOS Genetics, 19(2), e1010410. https://doi.org/10.1371/journal.pgen.1010410
Poulsgaard, G. A., Sørensen, S. G., Juul, R. I., Nielsen, M. M., & Pedersen, J. S. (2023). Sequence dependencies and mutation rates of localized mutational processes in cancer. Genome Medicine, 15(1). https://doi.org/10.1186/s13073-023-01217-z
Christensen, M. H., Drue, S. O., Rasmussen, M. H., Frydendahl, A., Lyskjær, I., Demuth, C., Nors, J., Gotschalck, K. A., Iversen, L. H., Andersen, C. L., & Pedersen, J. S. (2023). DREAMS: deep read-level error model for sequencing data applied to low-frequency variant calling and circulating tumor DNA detection. Genome Biology, 24(1). https://doi.org/10.1186/s13059-023-02920-1
Bornhofen, E., Fè, D., Nagy, I., Lenk, I., Greve, M., Didion, T., Jensen, C. S., Asp, T., & Janss, L. (2023). Genetic architecture of inter-specific and -generic grass hybrids by network analysis on multi-omics data. BMC Genomics, 24(1). https://doi.org/10.1186/s12864-023-09292-7
Song, D. J., Lanham, N. S., Ahmed, R., Knudsen, M. L., Levine, W. N., & Jobin, C. M. (2023). Post-operative Baseplate Radiographic Evaluation Using Routine pre-Operative CT. Journal of Shoulder and Elbow Arthroplasty, 7. https://doi.org/10.1177/24715492231211122
Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J., Murnyak, B., Wendt, F., Adams, M., Campos, A. I., DiBlasi, E., Fullerton, J. M., Kranzler, H. R., Bakian, A. V., Monson, E. T., Rentería, M. E., Walss-Bass, C., … Andreassen, O. A. (2023). GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. American Journal of Psychiatry, 180(10), 723–738. https://doi.org/10.1176/appi.ajp.21121266
Brikell, I., Wimberley, T., Albiñana, C., Vilhjálmsson, B. J., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, T., Hougaard, D. M., Nordentoft, M., Mors, O., Mortensen, P. B., Petersen, L. V., & Dalsgaard, S. (2022). Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.21111105
Christensen, E., Nordentoft, I., Birkenkamp-Demtröder, K., Elbæk, S. K., Lindskrog, S. V., Taber, A., Andreasen, T. G., Strandgaard, T., Knudsen, M., Lamy, P., Agerbæk, M., Jensen, J. B., & Dyrskjøt, L. (2023). Cell-Free Urine and Plasma DNA Mutational Analysis Predicts Neoadjuvant Chemotherapy Response and Outcome in Patients with Muscle-Invasive Bladder Cancer. Clinical Cancer Research, OF1–OF10. https://doi.org/10.1158/1078-0432.ccr-22-3250
Gao, H., Hamp, T., Ede, J., Schraiber, J. G., McRae, J., Singer-Berk, M., Yang, Y., Dietrich, A. S. D., Fiziev, P. P., Kuderna, L. F. K., Sundaram, L., Wu, Y., Adhikari, A., Field, Y., Chen, C., Batzoglou, S., Aguet, F., Lemire, G., Reimers, R., … Farh, K. K.-H. (2023). The landscape of tolerated genetic variation in humans and primates. Science, 380(6648). https://doi.org/10.1126/science.abn8197
Sørensen, E. F., Harris, R. A., Zhang, L., Raveendran, M., Kuderna, L. F. K., Walker, J. A., Storer, J. M., Kuhlwilm, M., Fontsere, C., Seshadri, L., Bergey, C. M., Burrell, A. S., Bergman, J., Phillips-Conroy, J. E., Shiferaw, F., Chiou, K. L., Chuma, I. S., Keyyu, J. D., Fischer, J., … Rogers, J. (2023). Genome-wide coancestry reveals details of ancient and recent male-driven reticulation in baboons. Science, 380(6648). https://doi.org/10.1126/science.abn8153
Kuderna, L. F. K., Gao, H., Janiak, M. C., Kuhlwilm, M., Orkin, J. D., Bataillon, T., Manu, S., Valenzuela, A., Bergman, J., Rousselle, M., Silva, F. E., Agueda, L., Blanc, J., Gut, M., de Vries, D., Goodhead, I., Harris, R. A., Raveendran, M., Jensen, A., … Marques Bonet, T. (2023). A global catalog of whole-genome diversity from 233 primate species. Science, 380(6648), 906–913. https://doi.org/10.1126/science.abn7829
Shao, Y., Zhou, L., Li, F., Zhao, L., Zhang, B.-L., Shao, F., Chen, J.-W., Chen, C.-Y., Bi, X., Zhuang, X.-L., Zhu, H.-L., Hu, J., Sun, Z., Li, X., Wang, D., Rivas-González, I., Wang, S., Wang, Y.-M., Chen, W., … Wu, D.-D. (2023). Phylogenomic analyses provide insights into primate evolution. Science, 380(6648), 913–924. https://doi.org/10.1126/science.abn6919
Rivas-González, I., Rousselle, M., Li, F., Zhou, L., Dutheil, J. Y., Munch, K., Shao, Y., Wu, D., Schierup, M. H., & Zhang, G. (2023). Pervasive incomplete lineage sorting illuminates speciation and selection in primates. Science, 380(6648). https://doi.org/10.1126/science.abn4409
Zhang, B.-L., Chen, W., Wang, Z., Pang, W., Luo, M.-T., Wang, S., Shao, Y., He, W.-Q., Deng, Y., Zhou, L., Chen, J., Yang, M.-M., Wu, Y., Wang, L., Fernández-Bellon, H., Molloy, S., Meunier, H., Wanert, F., Kuderna, L., … Wu, D.-D. (2023). Comparative genomics reveals the hybrid origin of a macaque group. Science Advances, 9(22). https://doi.org/10.1126/sciadv.add3580
Feng, X., Liu, S., Sui, X., Chen, Y., Zhu, R., Jia, Y., Tong, J., Yu, X., Liu, C., & Hansen, M. M. (2023). Genetic responses in sexual diploid and unisexual triploid goldfish ( Carassius auratus ) introduced into a high‐altitude environment. Molecular Ecology. Portico. https://doi.org/10.1111/mec.16864
Thomassen, E. E., Sigsgaard, E. E., Jensen, M. R., Olsen, K., Hansen, M. D. D., Svenning, J., & Thomsen, P. F. (2023). Contrasting seasonal patterns in diet and dung‐associated invertebrates of feral cattle and horses in a rewilding area. Molecular Ecology. Portico. https://doi.org/10.1111/mec.16847
Rose, C., Lund, M. B., Schramm, A., Bilde, T., & Bechsgaard, J. (2023). Does ecological drift explain variation in microbiome composition among groups in a social host species? Journal of Evolutionary Biology. Portico. https://doi.org/10.1111/jeb.14228
Kazemi Naeini, M., Akbarzadeh, M., Kazemi, I., Speed, D., & Hosseini, S. M. (2023). Using the Bayesian variational spike and slab model in a genome‐wide association study for finding associated loci with bipolar disorder. Annals of Human Genetics, 88(3), 212–246. Portico. https://doi.org/10.1111/ahg.12538
Johannsen, B. M. W., Larsen, J. T., Liu, X., Madsen, K. B., Mægbæk, M. L., Albiñana, C., Bergink, V., Laursen, T. M., Bech, B. H., Mortensen, P. B., Nordentoft, M., Børglum, A. D., Werge, T., Hougaard, D. M., Agerbo, E., Petersen, L. V., & Munk‐Olsen, T. (2023). Identification of women at high risk of postpartum psychiatric episodes: A population‐based study quantifying relative and absolute risks following exposure to selected risk factors and genetic liability. Acta Psychiatrica Scandinavica. Portico. https://doi.org/10.1111/acps.13622
Balbuena, L., Peters, E., & Speed, D. (2023). Using polygenic risk scores to investigate the evolution of smoking and mental health outcomes in UK biobank participants. Acta Psychiatrica Scandinavica, 148(5), 447–456. Portico. https://doi.org/10.1111/acps.13601
Lassen, J. K., Wang, T., Nielsen, K. L., Hasselstrøm, J. B., Johannsen, M., & Villesen, P. (2023). Large‐Scale metabolomics: Predicting biological age using 10,133 routine untargeted LC–MS measurements. Aging Cell. Portico. https://doi.org/10.1111/acel.13813
Frydendahl, A., Rasmussen, M. H., Jensen, S. Ø., Henriksen, T. V., Demuth, C., Diekema, M., Ditzel, H. J., Wen, S. W. C., Pedersen, J. S., Dyrskjøt, L., & Andersen, C. L. (2023). Error-corrected deep targeted sequencing of circulating cell-free DNA from colorectal cancer patients for sensitive detection of circulating tumor DNA. https://doi.org/10.1101/2023.12.22.573042
Wu, X., Geller, F., Helenius, D., Grove, J., Albiñana, C., Petersen, L. V., Bulik, C. M., Børglum, A. D., Werge, T., Vilhjálmsson, B. J., & Feenstra, B. (2023). Mendelian randomization study of birth weight and risk of psychiatric disorders later in life. https://doi.org/10.1101/2023.10.26.23297618
O’Connell, K. S., Koromina, M., van der Veen, T., Boltz, T., David, F. S., Kay Yang, J. M., Lin, K.-H., Wang, X., Coleman, J. R. I., Mitchell, B. L., McGrouther, C. C., Rangan, A. V., Lind, P. A., Koch, E., Harder, A., Parker, N., Bendl, J., Adorjan, K., … Agerbo, E. (2023). Genomics yields biological and phenotypic insights into bipolar disorder. https://doi.org/10.1101/2023.10.07.23296687
Henry, A., Mo, X., Finan, C., Chaffin, M. D., Speed, D., Issa, H., Denaxas, S., Ware, J. S., Zheng, S. L., Malarstig, A., Gratton, J., Bond, I., Roselli, C., Miller, D., Chopade, S., Schmidt, A. F., Abner, E., Adams, L., … Andersson, C. (2023). Mapping the aetiological foundations of the heart failure spectrum using human genetics. https://doi.org/10.1101/2023.10.01.23296379
Zheng, S. L., Henry, A., Cannie, D., Lee, M., Miller, D., McGurk, K. A., Bond, I., Xu, X., Issa, H., Francis, C., De Marvao, A., Theotokis, P. I., Buchan, R. J., Speed, D., Abner, E., Adams, L., Aragam, K. G., Ärnlöv, J., … Axelsson Raja, A. (2023). Genome-wide association analysis reveals insights into the molecular etiology underlying dilated cardiomyopathy. https://doi.org/10.1101/2023.09.28.23295408
Okholm, T. L. H., Kamstrup, A. B., Nielsen, M. M., Hollensen, A. K., Graversgaard, M. L., Kristensen, L. S., Vang, S., Park, S. S., Yeo, G. W., Dyrskjøt, L., Kjems, J., Pedersen, J. S., & Damgaard, C. K. (2023). circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA. https://doi.org/10.1101/2023.09.14.557527
Vaez, M., Montalbano, S., Calle Sánchez, X., Georgii Hellberg, K.-L., Rasekhi Dehkordi, S., Dybdahl Krebs, M., Meijsen, J., Shorter, J., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Geschwind, D. H., Buil, A., Schork, A. J., Helenius, D., Raznahan, A., … Thompson, W. K. (2023). Population-based Risk of Psychiatric Disorders Associated with Recurrent CNVs. https://doi.org/10.1101/2023.09.04.23294975
Bergstedt, J., Pasman, J. A., Ma, Z., Harder, A., Yao, S., Parker, N., Treur, J. L., Smit, D. J. A., Frei, O., Shadrin, A., Meijsen, J. J., Shen, Q., Tornvall, P., Buil, A., Werge, T., Hjerling-Leffler, J., Als, T. D., Børglum, A. D., Lewis, C. M., … Fang, F. (2023). Distinct biological signature and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease. https://doi.org/10.1101/2023.09.01.23294931
Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C.-Y., Choi, K. W., Coleman, J. R., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babic, D., Bacanu, S.-A., … Koenen, K. C. (2023). Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. https://doi.org/10.1101/2023.08.31.23294915
Speed, D., & Evans, D. M. (2023). Estimating disease heritability from complex pedigrees allowing for ascertainment and covariates. https://doi.org/10.1101/2023.07.13.23292588
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Sartori, I., Walnum, H. T., Skeie, K. S., Georges, L., Knudsen, M. D., Bacher, P., Candanedo, J., Sigounis, A.-M., Prakash, A. K., Pritoni, M., Granderson, J., Yang, S., & Wan, M. P. (2023). Sub-hourly measurement datasets from 6 real buildings: Energy use and indoor climate. Data in Brief, 48, 109149. https://doi.org/10.1016/j.dib.2023.109149
Jefsen, O. H., Holde, K., McGrath, J. J., Rajagopal, V. M., Albiñana, C., Vilhjálmsson, B. J., Grove, J., Agerbo, E., Yilmaz, Z., Plana-Ripoll, O., Munk-Olsen, T., Demontis, D., Børglum, A., Mors, O., Bulik, C. M., Mortensen, P. B., & Petersen, L. V. (2023). Polygenic Risk of Mental Disorders and Subject-Specific School Grades. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2023.11.020
Wendt, F. R., Garcia-Argibay, M., Cabrera-Mendoza, B., Valdimarsdóttir, U. A., Gelernter, J., Stein, M. B., Nivard, M. G., Maihofer, A. X., Nievergelt, C. M., Larsson, H., Mattheisen, M., Polimanti, R., Meier, S. M., Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., … Nievergelt, C. M. (2022). The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study. Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2022.08.012
Wang, X., Walker, A., Revez, J. A., Ni, G., Adams, M. J., McIntosh, A. M., Visscher, P. M., Wray, N. R., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S.-A., … Sullivan, P. F. (2023). Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability. The American Journal of Human Genetics, 110(7), 1207–1215. https://doi.org/10.1016/j.ajhg.2023.06.006
Berrandou, T.-E., Balding, D., & Speed, D. (2023). LDAK-GBAT: Fast and powerful gene-based association testing using summary statistics. The American Journal of Human Genetics, 110(1), 23–29. https://doi.org/10.1016/j.ajhg.2022.11.010
Kretsch, R. C., Andersen, E. S., Bujnicki, J. M., Chiu, W., Das, R., Luo, B., Masquida, B., McRae, E. K. S., Schroeder, G. M., Su, Z., Wedekind, J. E., Xu, L., Zhang, K., Zheludev, I. N., Moult, J., & Kryshtafovych, A. (2023). RNA target highlights in CASP15: Evaluation of predicted models by structure providers. Proteins: Structure, Function, and Bioinformatics. Portico. https://doi.org/10.1002/prot.26550
Patel, K. H. S., Walters, G. B., Stefánsson, H., Stefánsson, K., Degenhardt, F., Nothen, M., Van Der Veen, T., Demontis, D., Borglum, A., Kristiansen, M., Bass, N. J., & McQuillin, A. (2023). Predicting ADHD in alcohol dependence using polygenic risk scores for ADHD. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Portico. https://doi.org/10.1002/ajmg.b.32967
Shi, Y., Sprooten, E., Mulders, P., Vrijsen, J., Bralten, J., Demontis, D., Børglum, A. D., Walters, G. B., Stefansson, K., van Eijndhoven, P., Tendolkar, I., Franke, B., & Mota, N. R. (2023). Multi‐polygenic scores in psychiatry: From disorder specific to transdiagnostic perspectives. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. Portico. https://doi.org/10.1002/ajmg.b.32951
Kimbrel, N. A., Ashley-Koch, A. E., Qin, X. J., Lindquist, J. H., Garrett, M. E., Dennis, M. F., Hair, L. P., Huffman, J. E., Jacobson, D. A., Madduri, R. K., Trafton, J. A., Coon, H., Docherty, A. R., Mullins, N., Ruderfer, D. M., Harvey, P. D., McMahon, B. H., Oslin, D. W., … Beckham, J. C. (2022). Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2022.3896

2022

(126 publications)

Bergeron, L. A., Besenbacher, S., Turner, T., Versoza, C. J., Wang, R. J., Price, A. L., Armstrong, E., Riera, M., Carlson, J., Chen, H., Hahn, M. W., Harris, K., Kleppe, A. S., López-Nandam, E. H., Moorjani, P., Pfeifer, S. P., Tiley, G. P., Yoder, A. D., Zhang, G., & Schierup, M. H. (2022). The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.73577
Renaud, G., Nørgaard, M., Lindberg, J., Grönberg, H., De Laere, B., Jensen, J. B., Borre, M., Andersen, C. L., Sørensen, K. D., Maretty, L., & Besenbacher, S. (2022). Unsupervised detection of fragment length signatures of circulating tumor DNA using non-negative matrix factorization. ELife, 11. CLOCKSS. https://doi.org/10.7554/elife.71569
Wimberley, T., Brikell, I., Pedersen, E. M., Agerbo, E., Vilhjálmsson, B. J., Albiñana, C., Privé, F., Thapar, A., Langley, K., Riglin, L., Simonsen, M., Nielsen, H. S., Børglum, A. D., Nordentoft, M., Mortensen, P. B., & Dalsgaard, S. (2022). Early-Life Injuries and the Development of Attention-Deficit/Hyperactivity Disorder. The Journal of Clinical Psychiatry, 83(1). https://doi.org/10.4088/jcp.21m14033
Hansen, P. B., Ruud, A. K., de los Campos, G., Malinowska, M., Nagy, I., Svane, S. F., Thorup-Kristensen, K., Jensen, J. D., Krusell, L., & Asp, T. (2022). Integration of DNA Methylation and Transcriptome Data Improves Complex Trait Prediction in Hordeum vulgare. Plants, 11(17), 2190. https://doi.org/10.3390/plants11172190
Wang, T., Nielsen, K. L., Frisch, K., Lassen, J. K., Nielsen, C. B., Andersen, C. U., Villesen, P., Andreasen, M. F., Hasselstrøm, J. B., & Johannsen, M. (2022). A Retrospective Metabolomics Analysis of Gamma-Hydroxybutyrate in Humans: New Potential Markers and Changes in Metabolism Related to GHB Consumption. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.816376
Agersnap, S., Sigsgaard, E. E., Jensen, M. R., Avila, M. D. P., Carl, H., Møller, P. R., Krøs, S. L., Knudsen, S. W., Wisz, M. S., & Thomsen, P. F. (2022). A National Scale “BioBlitz” Using Citizen Science and eDNA Metabarcoding for Monitoring Coastal Marine Fish. Frontiers in Marine Science, 9. https://doi.org/10.3389/fmars.2022.824100
Volkmann, A., Koopman, G., Mooij, P., Verschoor, E. J., Verstrepen, B. E., Bogers, W. M. J. M., Idorn, M., Paludan, S. R., Vang, S., Nielsen, M. A., Sander, A. F., Schmittwolf, C., Hochrein, H., & Chaplin, P. (2022). A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.857440
Sterenborg, R. B. T. M., Galesloot, T. E., Teumer, A., Netea-Maier, R. T., Speed, D., Meima, M. E., Visser, W. E., Smit, J. W. A., Peeters, R. P., & Medici, M. (2022). The Effects of Common Genetic Variation in 96 Genes Involved in Thyroid Hormone Regulation on TSH and FT4 Concentrations. The Journal of Clinical Endocrinology & Metabolism, 107(6), e2276–e2283. https://doi.org/10.1210/clinem/dgac136
Michaelsen, T. Y., Bennedbæk, M., Christiansen, L. E., Jørgensen, M. S. F., Møller, C. H., Sørensen, E. A., Knutsson, S., Brandt, J., Jensen, T. B. N., Chiche-Lapierre, C., Collados, E. F., Sørensen, T., Petersen, C., Le-Quy, V., Sereika, M., Hansen, F. T., Rasmussen, M., Fonager, J., … Karst, S. M. (2022). Introduction and transmission of SARS-CoV-2 lineage B.1.1.7, Alpha variant, in Denmark. Genome Medicine, 14(1). https://doi.org/10.1186/s13073-022-01045-7
Hansen, E. B., Fredsøe, J., Okholm, T. L. H., Ulhøi, B. P., Klingenberg, S., Jensen, J. B., Kjems, J., Bouchelouche, K., Borre, M., Damgaard, C. K., Pedersen, J. S., Kristensen, L. S., & Sørensen, K. D. (2022). The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer. Genome Medicine, 14(1). https://doi.org/10.1186/s13073-021-01009-3
Bergman, J., & Schierup, M. H. (2022). Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes. Genome Biology, 23(1). https://doi.org/10.1186/s13059-022-02784-x
Knorr, S., Skakkebæk, A., Just, J., Johannsen, E. B., Trolle, C., Vang, S., Lohse, Z., Bytoft, B., Damm, P., Højlund, K., Jensen, D. M., & Gravholt, C. H. (2022). Epigenetic and transcriptomic alterations in offspring born to women with type 1 diabetes (the EPICOM study). BMC Medicine, 20(1). https://doi.org/10.1186/s12916-022-02514-x
Nagy, I., Veeckman, E., Liu, C., Bel, M. V., Vandepoele, K., Jensen, C. S., Ruttink, T., & Asp, T. (2022). Chromosome-scale assembly and annotation of the perennial ryegrass genome. BMC Genomics, 23(1). https://doi.org/10.1186/s12864-022-08697-0
Christensen, K. J., Dreier, J. W., Skotte, L., Feenstra, B., Grove, J., Børglum, A. D., Mitrovic, M., Cotsapas, C., & Christensen, J. (2022). Seasonal variation and risk of febrile seizures; a Danish nationwide cohort study. Neuroepidemiology. Portico. https://doi.org/10.1159/000522065
Sokač, M., Ahrenfeldt, J., Litchfield, K., Watkins, T. B. K., Knudsen, M., Dyrskjøt, L., Jakobsen, M. R., & Birkbak, N. J. (2022). Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer. Cancer Research Communications, 2(8), 762–771. https://doi.org/10.1158/2767-9764.crc-22-0047
Grace, C. A., Sousa Carvalho, K. S., Sousa Lima, M. I., Costa Silva, V., Reis-Cunha, J. L., Brune, M. J., Forrester, S., Pedrozo e Silva de Azevedo, C. de M., Costa, D. L., Speed, D., Mottram, J. C., Jeffares, D. C., & Costa, C. H. N. (2022). Parasite Genotype Is a Major Predictor of Mortality from Visceral Leishmaniasis. MBio, 13(6). https://doi.org/10.1128/mbio.02068-22
Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, M., Børglum, A. D., Hougaard, D. M., Werge, T., Rasmussen, S., & Benros, M. E. (2022). Deep learning–based integration of genetics with registry data for stratification of schizophrenia and depression. Science Advances, 8(26). https://doi.org/10.1126/sciadv.abi7293
Aagaard, A., Liu, S., Tregenza, T., Braad Lund, M., Schramm, A., Verhoeven, K. J. F., Bechsgaard, J., & Bilde, T. (2022). Adapting to climate with limited genetic diversity: Nucleotide, DNA methylation and microbiome variation among populations of the social spider Stegodyphus dumicola. Molecular Ecology, 31(22), 5765–5783. Portico. https://doi.org/10.1111/mec.16696
Liu, S., Tengstedt, A. N. B., Jacobsen, M. W., Pujolar, J. M., Jónsson, B., Lobón‐Cervià, J., Bernatchez, L., & Hansen, M. M. (2022). Genome‐wide methylation in the panmictic European eel ( Anguilla anguilla ). Molecular Ecology, 31(16), 4286–4306. Portico. https://doi.org/10.1111/mec.16586
Knutsen, H., Catarino, D., Rogers, L., Sodeland, M., Mattingsdal, M., Jahnke, M., Hutchings, J. A., Mellerud, I., Espeland, S. H., Johanneson, K., Roth, O., Hansen, M. M., Jentoft, S., André, C., & Jorde, P. E. (2022). Combining population genomics with demographic analyses highlights habitat patchiness and larval dispersal as determinants of connectivity in coastal fish species. Molecular Ecology. Portico. https://doi.org/10.1111/mec.16415
Matzke, M., Toft, S., Bechsgaard, J., Vilstrup, A., Uhl, G., Künzel, S., Tuni, C., & Bilde, T. (2022). Sperm competition intensity affects sperm precedence patterns in a polyandrous gift‐giving spider. Molecular Ecology, 31(8), 2435–2452. Portico. https://doi.org/10.1111/mec.16405
Rose, C., Kyneb, S., Schou, M. F., Bechsgaard, J., & Bilde, T. (2022). The role of inter‐individual intolerance in group cohesion and the transition to sociality in spiders. Journal of Evolutionary Biology, 35(7), 1020–1026. Portico. https://doi.org/10.1111/jeb.14032
Walter, A., & Bilde, T. (2022). Avoiding the tragedy of the commons: Improved group‐feeding performance in kin groups maintains foraging cooperation in subsocial Stegodyphus africanus spiders (Araneae, Eresidae). Journal of Evolutionary Biology, 35(3), 391–399. Portico. https://doi.org/10.1111/jeb.13976
Charmouh, A. P., Reid, J. M., Bilde, T., & Bocedi, G. (2022). Eco‐evolutionary extinction and recolonization dynamics reduce genetic load and increase time to extinction in highly inbred populations. Evolution. Portico. https://doi.org/10.1111/evo.14620
Byg, L. M., Speed, M., Speed, D., & Østergaard, S. D. (2022). Genetic liability to bipolar disorder and body mass index: A bidirectional two‐sample Mendelian randomization study. Bipolar Disorders, 25(1), 25–31. Portico. https://doi.org/10.1111/bdi.13267
Kingsley, N. B., Sandmeyer, L., Norton, E. M., Speed, D., Dwyer, A., Lassaline, M., McCue, M., & Bellone, R. R. (2022). Heritability of insidious uveitis in Appaloosa horses. Animal Genetics, 53(6), 872–877. Portico. https://doi.org/10.1111/age.13267
Debost, J. P. G., Thorsteinsson, E., Trabjerg, B., Benros, M. E., Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, T., Mortensen, P. B., Agerbo, E., & Petersen, L. V. (2022). Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders. Acta Psychiatrica Scandinavica, 146(5), 406–419. Portico. https://doi.org/10.1111/acps.13491
Wilcox, T. M., & Jensen, M. R. (2022). Drawing a line in the sand: Environmental DNA population genomics. Molecular Ecology Resources, 22(7), 2455–2457. Portico. https://doi.org/10.1111/1755-0998.13686
Thomsen, A. H., Leth, P. M., Hougen, H. P., & Villesen, P. (2022). Blunt force homicides in Denmark 1992–2016. Journal of Forensic Sciences, 67(6), 2343–2350. Portico. https://doi.org/10.1111/1556-4029.15118
Bornhofen, E., Fè, D., Nagy, I., Lenk, I., Greve, M., Didion, T., Jensen, C. S., Asp, T., & Janss, L. (2022). Genetic architecture of inter-specific and -generic grass hybrids by network analysis on multi-omics data. https://doi.org/10.1101/2022.12.23.521625
Rubæk Holm, A. M., Knudsen, S. W., Månsson, M., Pedersen, D. E., Nordfoss, P. H., Johansson, D. K., Gramsbergen, M., Havmøller, R. W., Sigsgaard, E. E., Thomsen, P. F., Olsen, M. T., & Møller, P. R. (2022). Holistic monitoring of freshwater and terrestrial vertebrates by camera trapping and environmental DNA. https://doi.org/10.1101/2022.11.23.517571
Lauterbur, M. E., Munch, K., & Enard, D. (2022). Versatile detection of diverse selective sweeps with Flex-sweep. https://doi.org/10.1101/2022.11.15.516494
Borbye-Lorenzen, N., Zhu, Z., Agerbo, E., Albiñana, C., Benros, M. E., Bian, B., Børglum, A. D., Bulik, C. M., Goldtsche Debost, J.-C. P., Grove, J., Hougaard, D. M., McRae, A. F., Mors, O., Mortensen, P. B., Musliner, K. L., Nordentoft, M., Petersen, L. V., Privé, F., Sidorenko, J., … McGrath, J. J. (2022). The genetic and phenotypic correlates of neonatal Complement Component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders. https://doi.org/10.1101/2022.11.09.22281216
Lindskrog, S. V., Schmøkel, S. S., Nordentoft, I., Lamy, P., Knudsen, M., Prip, F., Strandgaard, T., Jensen, J. B., & Dyrskjøt, L. (2022). Single nucleus and spatially resolved intra-tumor subtype heterogeneity in bladder cancer. https://doi.org/10.1101/2022.10.27.513983
Christensen, E., Nordentoft, I., Elbæk, S. K., Birkenkamp-Demtröder, K., Taber, A., Andreasen, T. G., Strandgaard, T., Knudsen, M., Lamy, P., Agerbæk, M., Jensen, J. B., & Dyrskjøt, L. (2022). Cell-free urine- and plasma DNA mutational analysis predicts neoadjuvant chemotherapy response and outcome in patients with muscle invasive bladder cancer. https://doi.org/10.1101/2022.10.24.22281440
Schmøkel, S. S., Nordentoft, I. K., Lindskrog, S. V., Lamy, P., Knudsen, M., Jensen, J. B., & Dyrskjøt, L. (2022). Improved Protocol for Single Nucleus RNA-sequencing of Frozen Human Bladder Tumor Biopsies. https://doi.org/10.1101/2022.10.14.512220
Witteveen, M. J., Pedersen, E. M., Meijsen, J., Andersen, M. R., Privé, F., Speed, D., & Vilhjálmsson, B. J. (2022). Publicly Available Privacy-preserving Benchmarks for Polygenic Prediction. https://doi.org/10.1101/2022.10.10.510645
Schoeler, T., Speed, D., Porcu, E., Pirastu, N., Pingault, J.-B., & Kutalik, Z. (2022). Correction for participation bias in the UK Biobank reveals non-negligible impact on genetic associations and downstream analyses. https://doi.org/10.1101/2022.09.28.509845
Christensen, M. H., Drue, S., Rasmussen, M. H., Frydendahl, A., Lyskjær, I., Demuth, C., Nors, J., Gotschalck, K. A., Iversen, L. H., Andersen, C. L., & Pedersen, J. S. (2022). DREAMS: Deep Read-level Error Model for Sequencing data applied to low-frequency variant calling and circulating tumor DNA detection. https://doi.org/10.1101/2022.09.27.509150
Albiñana, C., Zhu, Z., Schork, A. J., Ingason, A., Aschard, H., Brikell, I., Bulik, C. M., Petersen, L. V., Agerbo, E., Grove, J., Nordentoft, M., Hougaard, D. M., Werge, T., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Neale, B. M., Privé, F., & Vilhjálmsson, B. J. (2022). Multi-PGS enhances polygenic prediction: weighting 937 polygenic scores. https://doi.org/10.1101/2022.09.14.22279940
Nielsen, S. V., Vaughn, A. H., Leppälä, K., Landis, M. J., Mailund, T., & Nielsen, R. (2022). Bayesian inference of admixture graphs on Native American and Arctic populations. https://doi.org/10.1101/2022.09.06.506725
Als, T. D., Kurki, M., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D., Bendl, J., Bybjerg-Grauholm, J., Zheng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., … Walters, B. (2022). Identification of 64 new risk loci for major depression, refinement of the genetic architecture and risk prediction of recurrence and comorbidities. https://doi.org/10.1101/2022.08.24.22279149
Munch, T. N., Hedley, P. L., Hagen, C. M., Elson, J., Bækvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A., Mortensen, P. B., Werge, T. M., Melbye, M., Hougaard, D. M., & Christiansen, M. (2022). Mitochondrial DNA haplogroup variation in hydrocephalus. https://doi.org/10.1101/2022.08.15.22278803
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Steinbach, J., Krebs, M. D., Hougaard, D. M., Werge, T., Nordentoft, M., Børglum, A. D., Musliner, K. L., Ganna, A., Schork, A. J., Mortensen, P. B., McGrath, J. J., Privé, F., & Vilhjálmsson, B. J. (2022). ADuLT: An efficient and robust time-to-event GWAS. https://doi.org/10.1101/2022.08.11.22278618
Grace, C. A., Sousa Carvalho, K. S., Sousa Lima, M. I., Silva, V. C., Reis-Cunha, J. L., Brune, M. J., Forrester, S., Pedrozo e Silva de Azevedo, C. de M., Costa, D. L., Speed, D., Mottram, J. C., Jeffares, D. C., & Costa, C. H. N. (2022). Parasite genotype is a major predictor of mortality from visceral leishmaniasis. https://doi.org/10.1101/2022.07.28.501951
Rohner, M., Manzanares, C., Yates, S., Thorogood, D., Copetti, D., Lübberstedt, T., Asp, T., & Studer, B. (2022). Fine-mapping and comparative genomic analysis reveal the gene composition at the S and Z self-incompatibility loci in grasses. https://doi.org/10.1101/2022.07.18.499170
Berrandou, T.-E., Balding, D., & Speed, D. (2022). LDAK-GBAT: fast and powerful gene-based association testing using summary statistics. https://doi.org/10.1101/2022.07.01.22277161
Appadurai, V., Grauholm, J., Krebs, M., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Mortensen, P. B., Delaneau, O., Werge, T., & Schork, A. J. (2022). Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks. https://doi.org/10.1101/2022.06.27.497703
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., … McGrath, J. J. (2022). Genetic correlates of vitamin D-binding protein and 25 hydroxyvitamin D in neonatal dried blood spots. https://doi.org/10.1101/2022.06.08.22276164
Moses, M., Tiego, J., Demontis, D., Walters, G. B., Stefansson, H., Stefansson, K., Børglum, A. D., Arnatkeviciute, A., & Bellgrove, M. A. (2022). Working memory and reaction time variability mediate the relationship between polygenic risk and ADHD traits in a general population sample. https://doi.org/10.1101/2022.05.31.494251
Shi, Y., Sprooten, E., Mulders, P., Vrijsen, J., Bralten, J., Demontis, D., Børglum, A. D., Walters, G. B., Stefansson, K., van Eijndhoven, P., Tendolkar, I., Franke, B., & Mota, N. R. (2022). Multi-polygenic scores in psychiatry: from disorder-specific to transdiagnostic perspectives. https://doi.org/10.1101/2022.05.30.22275563
Bornhofen, E., Fè, D., Lenk, I., Greve, M., Didion, T., Jensen, C. S., Asp, T., & Janss, L. (2022). Leveraging spatio-temporal genomic breeding value estimates of dry matter yield and herbage quality in ryegrass via random regression models. https://doi.org/10.1101/2022.05.01.489357
Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Werge, T. M., Melbye, M., Hougaard, D. M., Larsen, L. A., Christensen, S. T., & Christiansen, M. (2022). The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement. https://doi.org/10.1101/2022.04.11.22273725
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Feng, S., Bai, M., Rivas-González, I., Li, C., Liu, S., Tong, Y., Yang, H., Chen, G., Xie, D., Sears, K. E., Franco, L. M., Gaitan-Espitia, J. D., Nespolo, R. F., Johnson, W. E., Yang, H., Brandies, P. A., Hogg, C. J., Belov, K., Renfree, M. B., … Zhang, G. (2022). Incomplete lineage sorting and phenotypic evolution in marsupials. Cell, 185(10), 1646-1660.e18. https://doi.org/10.1016/j.cell.2022.03.034
Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., … Musliner, K. L. (2022). Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample. Biological Psychiatry Global Open Science, 2(4), 400–410. https://doi.org/10.1016/j.bpsgos.2021.11.003
Pain, O., Hodgson, K., Trubetskoy, V., Ripke, S., Marshe, V. S., Adams, M. J., Byrne, E. M., Campos, A. I., Carrillo-Roa, T., Cattaneo, A., Als, T. D., Souery, D., Dernovsek, M. Z., Fabbri, C., Hayward, C., Henigsberg, N., Hauser, J., Kennedy, J. L., Lenze, E. J., … Sullivan, P. F. (2022). Identifying the Common Genetic Basis of Antidepressant Response. Biological Psychiatry Global Open Science, 2(2), 115–126. https://doi.org/10.1016/j.bpsgos.2021.07.008
Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., … Nievergelt, C. M. (2022). Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biological Psychiatry, 91(7), 626–636. https://doi.org/10.1016/j.biopsych.2021.09.020
Mullins, N., Kang, J., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M.-H., Watson, H. J., Adams, M., Awasthi, S., Gandal, M., Hafferty, J. D., Hishimoto, A., Kim, M., Okazaki, S., … Striker, R. (2022). Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry, 91(3), 313–327. https://doi.org/10.1016/j.biopsych.2021.05.029
Blokland, G. A. M., Grove, J., Chen, C.-Y., Cotsapas, C., Tobet, S., Handa, R., St Clair, D., Lencz, T., Mowry, B. J., Periyasamy, S., Cairns, M. J., Tooney, P. A., Wu, J. Q., Kelly, B., Kirov, G., Sullivan, P. F., Corvin, A., Riley, B. P., Esko, T., … Geschwind, D. (2022). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry, 91(1), 102–117. https://doi.org/10.1016/j.biopsych.2021.02.972
Marigi, E. M., Conte, S., Reinholz, A. K., Steubs, J. A., Knudsen, M. L., Krych, A. J., & Camp, C. L. (2022). Shoulder Injuries in Professional Baseball Batters: Analysis of 3,414 Injuries Over an 8-Year Period. Arthroscopy, Sports Medicine, and Rehabilitation, 4(3), e1119–e1126. https://doi.org/10.1016/j.asmr.2022.03.012
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., … Vilhjálmsson, B. J. (2022). Accounting for age of onset and family history improves power in genome-wide association studies. The American Journal of Human Genetics, 109(3), 417–432. https://doi.org/10.1016/j.ajhg.2022.01.009
Feng, X., Liu, S., & Hansen, M. M. (2022). Demographic history of two endangered Atlantic eel species, Anguilla anguilla and Anguilla rostrata. Conservation Genetics, 23(5), 981–987. https://doi.org/10.1007/s10592-022-01469-z
Thomsen, A. H., Leth, P. M., Hougen, H. P., & Villesen, P. (2022). Asphyxia homicides in Denmark 1992–2016. International Journal of Legal Medicine. https://doi.org/10.1007/s00414-022-02787-0
Barre, P., Asp, T., Byrne, S., Casler, M., Faville, M., Rognli, O. A., Roldan-Ruiz, I., Skøt, L., & Ghesquière, M. (2022). Genomic Prediction of Complex Traits in Forage Plants Species: Perennial Grasses Case. Genomic Prediction of Complex Traits, 521–541. https://doi.org/10.1007/978-1-0716-2205-6_19
Bornhofen, E., Fè, D., Lenk, I., Greve, M., Didion, T., Jensen, C. S., Asp, T., & Janss, L. (2022). Leveraging spatiotemporal genomic breeding value estimates of dry matter yield and herbage quality in ryegrass via random regression models. The Plant Genome. Portico. https://doi.org/10.1002/tpg2.20255
Malinowska, M., Ruud, A. K., Jensen, J., Svane, S. F., Smith, A. G., Bellucci, A., Lenk, I., Nagy, I., Fois, M., Didion, T., Thorup‐Kristensen, K., Jensen, C. S., & Asp, T. (2022). Relative importance of genotype, gene expression, and DNA methylation on complex traits in perennial ryegrass. The Plant Genome. Portico. https://doi.org/10.1002/tpg2.20253
Jeppesen, L. D., Lildballe, D. L., Hatt, L., Hedegaard, J., Singh, R., Toft, C. L. F., Schelde, P., Pedersen, A. S., Knudsen, M., & Vogel, I. (2022). Noninvasive prenatal screening for cystic fibrosis using circulating trophoblasts: Detection of the 50 most common disease‐causing variants. Prenatal Diagnosis, 43(1), 3–13. Portico. https://doi.org/10.1002/pd.6276
Reinert, T., Petersen, L. M. S., Henriksen, T. V., Larsen, M. Ø., Rasmussen, M. H., Johansen, A. F. B., Øgaard, N., Knudsen, M., Nordentoft, I., Vang, S., Krag, S. R. P., Knudsen, A. R., Mortensen, F. V., & Andersen, C. L. (2022). Circulating tumor DNA for prognosis assessment and postoperative management after curative‐intent resection of colorectal liver metastases. International Journal of Cancer, 150(9), 1537–1548. Portico. https://doi.org/10.1002/ijc.33924
Bataillon, T., Gauthier, P., Villesen, P., Santoni, S., Thompson, J. D., & Ehlers, B. K. (2022). From genotype to phenotype: Genetic redundancy and the maintenance of an adaptive polymorphism in the context of high gene flow. Evolution Letters, 6(2), 189–202. Portico. https://doi.org/10.1002/evl3.277
Klepke, M. J., Sigsgaard, E. E., Jensen, M. R., Olsen, K., & Thomsen, P. F. (2022). Accumulation and diversity of airborne, eukaryotic environmental DNA. Environmental DNA. Portico. https://doi.org/10.1002/edn3.340
Jensen, M. R., Sigsgaard, E. E., Ávila, M. de P., Agersnap, S., Brenner‐Larsen, W., Sengupta, M. E., Xing, Y., Krag, M. A., Knudsen, S. W., Carl, H., Møller, P. R., & Thomsen, P. F. (2022). Short‐term temporal variation of coastal marine eDNA. Environmental DNA, 4(4), 747–762. Portico. https://doi.org/10.1002/edn3.285
Speed, D., Kaphle, A., & Balding, D. J. (2022). SNP‐based heritability and selection analyses: Improved models and new results. BioEssays, 44(5). Portico. https://doi.org/10.1002/bies.202100170
Pardiñas, A. F., Smart, S. E., Willcocks, I. R., Holmans, P. A., Dennison, C. A., Lynham, A. J., Legge, S. E., Baune, B. T., Bigdeli, T. B., Cairns, M. J., Corvin, A., Fanous, A. H., Frank, J., Kelly, B., McQuillin, A., Melle, I., Mortensen, P. B., Mowry, B. J., … Pato, C. N. (2022). Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia. JAMA Psychiatry, 79(3), 260. https://doi.org/10.1001/jamapsychiatry.2021.3799
Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J., Pedersen, C., Hougaard, D. M., Børglum, A. D., Nordentoft, M., Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A., & Werge, T. (2022). Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders. JAMA Psychiatry, 79(1), 59. https://doi.org/10.1001/jamapsychiatry.2021.3392

2021

(91 publications)

Bayarri-Olmos, R., Johnsen, L. B., Idorn, M., Reinert, L. S., Rosbjerg, A., Vang, S., Hansen, C. B., Helgstrand, C., Bjelke, J. R., Bak-Thomsen, T., Paludan, S. R., Garred, P., & Skjoedt, M.-O. (2021). The alpha/B.1.1.7 SARS-CoV-2 variant exhibits significantly higher affinity for ACE-2 and requires lower inoculation doses to cause disease in K18-hACE2 mice. ELife, 10. CLOCKSS. https://doi.org/10.7554/elife.70002
Rose, C., Schramm, A., Irish, J., Bilde, T., & Bird, T. L. (2021). Host Plant Availability and Nest-Site Selection of the Social Spider Stegodyphus dumicola Pocock, 1898 (Eresidae). Insects, 13(1), 30. https://doi.org/10.3390/insects13010030
Fois, M., Bellucci, A., Malinowska, M., Greve, M., Ruud, A. K., & Asp, T. (2021). Genome-Wide Association Mapping of Crown and Brown Rust Resistance in Perennial Ryegrass. Genes, 13(1), 20. https://doi.org/10.3390/genes13010020
Lammers, A., Zweers, H., Sandfeld, T., Bilde, T., Garbeva, P., Schramm, A., & Lalk, M. (2021). Antimicrobial Compounds in the Volatilome of Social Spider Communities. Frontiers in Microbiology, 12. https://doi.org/10.3389/fmicb.2021.700693
Strom, N. I., Grove, J., Meier, S. M., Bækvad-Hansen, M., Becker Nissen, J., Damm Als, T., Halvorsen, M., Nordentoft, M., Mortensen, P. B., Hougaard, D. M., Werge, T., Mors, O., Børglum, A. D., Crowley, J. J., Bybjerg-Grauholm, J., & Mattheisen, M. (2021). Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis. Frontiers in Genetics, 12. https://doi.org/10.3389/fgene.2021.711624
Schork, A., LaBianca, S., Brickell, I., Helenius, D., Loughnan, R., Mefford, J., Palmer, C., Walker, R., Gådin, J., Krebs, M., Appadurai, V., Vaez, M., Agerbo, E., Pedersen, M. G., Børglum, A., Hougaard, D., Mors, O., Nordentoft, M., Mortensen, P., … Werge, T. (2021). Polygenic profiles define aspects of clinical heterogeneity in ADHD. https://doi.org/10.21203/rs.3.rs-702232/v1
Hansen, L. H., Rasmussen, T. L., & Villesen, P. (2021). Social Compliance During High Stringency Periods Efficiently Reduces COVID-19 Incidence: Evidence from Google Mobility Reports. https://doi.org/10.21203/rs.3.rs-501561/v1
Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, M., Børglum, A. D., Mortensen, P. B., Werge, T. M., Melbye, M., Hougaard, D. M., & Christiansen, M. (2021). Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study. https://doi.org/10.21203/rs.3.rs-41560/v2
Nazipi, S., Vangkilde-Pedersen, S. G., Busck, M. M., Lund, D. K., Marshall, I. P. G., Bilde, T., Lund, M. B., & Schramm, A. (2021). An antimicrobial Staphylococcus sciuri with broad temperature and salt spectrum isolated from the surface of the African social spider, Stegodyphus dumicola. https://doi.org/10.21203/rs.3.rs-186775/v1
Knorr, S., Skakkebæk, A., Just, J., Trolle, C., Vang, S., Lohse, Z., Bytoft, B., Damm, P., Højlund, K., Jensen, D., & Gravholt, C. (2021). Epigenetic And Transcriptomic Alterations in Offspring Born To Women With Type 1 Diabetes (The EPICOM Study). https://doi.org/10.21203/rs.3.rs-1046258/v1
Knudsen, M. L., & Levine, W. N. (2021). The Lesser Tuberosity Osteotomy Exposure for Total Shoulder Arthroplasty. JBJS Essential Surgical Techniques, 11(1), e19.00031-e19.00031. https://doi.org/10.2106/jbjs.st.19.00031
Gannon, N. P., Wise, K. L., & Knudsen, M. L. (2021). Advanced Templating for Total Shoulder Arthroplasty. JBJS Reviews, 9(3). https://doi.org/10.2106/jbjs.rvw.20.00089
Fu, Y., Thomas, A., Gasior, D., Harper, J., Gay, A., Jones, C., Hegarty, M., Asp, T., Fradera-Sola, A., Armstead, I., & Fernandez-Fuentes, N. (2021). A comparison of shared patterns of differential gene expression and gene ontologies in response to water-stress in roots and leaves of four diverse genotypes of Lolium and Festuca spp. temperate pasture grasses. PLOS ONE, 16(4), e0249636. https://doi.org/10.1371/journal.pone.0249636
Starnawska, A., Bukowski, L., Chernomorchenko, A., Elfving, B., Müller, H. K., van den Oord, E., Aberg, K., Guintivano, J., Grove, J., Mors, O., Børglum, A. D., Nielsen, A. L., Qvist, P., & Staunstrup, N. H. (2021). DNA methylation of the KLK8 gene in depression symptomatology. Clinical Epigenetics, 13(1). https://doi.org/10.1186/s13148-021-01184-5
Duval, E., Skaala, Ø., Quintela, M., Dahle, G., Delaval, A., Wennevik, V., Glover, K. A., & Hansen, M. M. (2021). Long-term monitoring of a brown trout (Salmo trutta) population reveals kin-associated migration patterns and contributions by resident trout to the anadromous run. BMC Ecology and Evolution, 21(1). https://doi.org/10.1186/s12862-021-01876-9
Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, M., Børglum, A. D., Mortensen, P. B., Werge, T. M., Melbye, M., Hougaard, D. M., & Christiansen, M. (2021). Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study. Journal of Neurodevelopmental Disorders, 13(1). https://doi.org/10.1186/s11689-021-09367-0
Brikell, I., Wimberley, T., Albiñana, C., Pedersen, E. M., Vilhjálmsson, B. J., Agerbo, E., Demontis, D., Børglum, A. D., Schork, A. J., LaBianca, S., Werge, T., Mors, O., Hougaard, D. M., Thapar, A., Mortensen, P. B., & Dalsgaard, S. (2021). Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD. American Journal of Psychiatry, 178(9), 854–864. https://doi.org/10.1176/appi.ajp.2020.20121686
Tregenza, T., Rodríguez‐Muñoz, R., Boonekamp, J. J., Hopwood, P. E., Sørensen, J. G., Bechsgaard, J., Settepani, V., Hegde, V., Waldie, C., May, E., Peters, C., Pennington, Z., Leone, P., Munk, E. M., Greenrod, S. T. E., Gosling, J., Coles, H., Gruffydd, R., Capria, L., … Bilde, T. (2021). Evidence for genetic isolation and local adaptation in the field cricket Gryllus campestris. Journal of Evolutionary Biology, 34(10), 1624–1636. Portico. https://doi.org/10.1111/jeb.13911
Stevelink, R., Luykx, J. J., Lin, B. D., Leu, C., Lal, D., Smith, A. W., Schijven, D., Carpay, J. A., Rademaker, K., Rodrigues Baldez, R. A., Devinsky, O., Braun, K. P. J., Jansen, F. E., Smit, D. J. A., & Koeleman, B. P. C. (2021). Shared genetic basis between genetic generalized epilepsy and background electroencephalographic oscillations. Epilepsia, 62(7), 1518–1527. Portico. https://doi.org/10.1111/epi.16922
Christensen, K. J., Dreier, J. W., Skotte, L., Feenstra, B., Grove, J., Børglum, A., Mitrovic, M., Cotsapas, C., & Christensen, J. (2021). Birth characteristics and risk of febrile seizures. Acta Neurologica Scandinavica, 144(1), 51–57. Portico. https://doi.org/10.1111/ane.13420
Jefsen, O. H., Speed, M., Speed, D., & Østergaard, S. D. (2021). Bipolar disorder and cannabis use: A bidirectional two‐sample Mendelian randomization study. Addiction Biology, 26(6). Portico. https://doi.org/10.1111/adb.13030
Dugal, L., Thomas, L., Jensen, M. R., Sigsgaard, E. E., Simpson, T., Jarman, S., Thomsen, P. F., & Meekan, M. (2021). Individual haplotyping of whale sharks from seawater environmental DNA. Molecular Ecology Resources, 22(1), 56–65. Portico. https://doi.org/10.1111/1755-0998.13451
Nielsen, S. M. B., Bilde, T., & Toft, S. (2021). Macronutrient niches and field limitation in a woodland assemblage of harvestmen. Journal of Animal Ecology, 91(3), 593–603. Portico. https://doi.org/10.1111/1365-2656.13649
Lan, T., Leppälä, K., Tomlin, C., Talbot, S. L., Sage, G. K., Farley, S., Shideler, R. T., Bachmann, L., Wiig, Ø., Albert, V. A., Salojärvi, J., Mailund, T., Drautz-Moses, D. I., Schuster, S. C., Herrera-Estrella, L., & Lindqvist, C. (2021). Insights into bear evolution from a Pleistocene polar bear genome. https://doi.org/10.1101/2021.12.11.472228
Bethune, J., Kleppe, A., & Besenbacher, S. (2021). A method to build extended sequence context models of point mutations and indels. https://doi.org/10.1101/2021.12.06.471476
Deak, J. D., Zhou, H., Galimberti, M., Levey, D., Wendt, F. R., Sanchez-Roige, S., Hatoum, A., Johnson, E. C., Nunez, Y. Z., Demontis, D., Børglum, A. D., Rajagopal, V. M., Jennings, M. V., Kember, R. L., Justice, A. C., Edenberg, H. J., Agrawal, A., Polimanti, R., Kranzler, H. R., & Gelernter, J. (2021). Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry. https://doi.org/10.1101/2021.12.04.21267094
Murat, F., Mbengue, N., Winge, S. B., Trefzer, T., Leushkin, E., Sepp, M., Cardoso-Moreira, M., Schmidt, J., Schneider, C., Mößinger, K., Brüning, T., Lamanna, F., Belles, M. R., Conrad, C., Kondova, I., Bontrop, R., Behr, R., Khaitovich, P., Pääbo, S., … Kaessmann, H. (2021). The molecular evolution of spermatogenesis across mammals. https://doi.org/10.1101/2021.11.08.467712
Eising, E., Mirza-Schreiber, N., de Zeeuw, E. L., Wang, C. A., Truong, D. T., Allegrini, A. G., Shapland, C. Y., Zhu, G., Wigg, K. G., Gerritse, M., Molz, B., Alagöz, G., Gialluisi, A., Abbondanza, F., Rimfeld, K., van Donkelaar, M., Liao, Z., Jansen, P. R., Andlauer, T. F. M., … Fisher, S. E. (2021). Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people. https://doi.org/10.1101/2021.11.04.466897
Poulsgaard, G. A., Sørensen, S. G., Juul, R. I., Nielsen, M. M., & Pedersen, J. S. (2021). Sequence dependencies and mutation rates of localized mutational processes in cancer. https://doi.org/10.1101/2021.10.27.465848
Mallawaarachchi, S., Tonkin-Hill, G., Croucher, N. J., Turner, P., Speed, D., Corander, J., & Balding, D. (2021). Genome-wide association, prediction and heritability in bacteria. https://doi.org/10.1101/2021.10.04.462983
Bergman, J., & Schierup, M. H. (2021). Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes. https://doi.org/10.1101/2021.09.14.460222
Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., … Musliner, K. L. (2021). Genome-wide by environment interaction study of stressful life events and hospital-treated depression in the iPSYCH2012 sample. https://doi.org/10.1101/2021.09.03.21262452
Bergeron, L. A., Besenbacher, S., Turner, T. N., Versoza, C. J., Wang, R. J., Price, A. L., Armstrong, E., Riera, M., Carlson, J., Chen, H., Hahn, M. W., Harris, K., Snøfrid Lo Natalie M Kleppe, A., López-Nandam, E. H., Moorjani, P., Pfeifer, S. P., Tiley, G. P., Yoder, A. D., Zhang, G., & Schierup, M. H. (2021). Mutationathon: towards standardization in estimates of pedigree-based germline mutation rates. https://doi.org/10.1101/2021.08.30.458162
Jefsen, O. H., Speed, M., Friston, K. J., Østergaard, S. D., & Speed, D. (2021). White matter disruption as a cause or consequence of schizophrenia: A Mendelian randomization study. https://doi.org/10.1101/2021.08.23.21262451
Brikell, I., Wimberley, T., Albiñana, C., Jóhann Vilhjálmsson, B., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, T., Hougaard, D. M., Nordentoft, M., Mors, O., Mortensen, P. B., Petersen, L. V., & Dalsgaard, S. (2021). Interplay of ADHD polygenic liability with birth-related, somatic and psychosocial factors in ADHD - a nationwide study. https://doi.org/10.1101/2021.08.18.21262211
Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Soler Artigas, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B., … Demontis, D. (2021). Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention deficit hyperactivity disorder. https://doi.org/10.1101/2021.08.06.21261679
LaBianca, S., Brikell, I., Helenius, D., Loughnan, R., Mefford, J., Palmer, C. E., Walker, R., Gådin, J. R., Krebs, M., Appadurai, V., Vaez, M., Agerbo, E., Gørtz Pedersen, M., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., Kendler, K. S., … Schork, A. J. (2021). Polygenic profiles define aspects of clinical heterogeneity in ADHD. https://doi.org/10.1101/2021.07.13.21260299
Renaud, G., Nørgaard, M., Lindberg, J., Grönberg, H., De Laere, B., Jensen, J. B., Borre, M., Andersen, C. L., Sørensen, K. D., Maretty, L., & Besenbacher, S. (2021). Discovering fragment length signatures of circulating tumor DNA using Non-negative Matrix Factorization. https://doi.org/10.1101/2021.06.09.447533
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2020

(111 publications)

Cagnano, G., Vázquez-de-Aldana, B. R., Asp, T., Roulund, N., Jensen, C. S., & Soto-Barajas, M. C. (2020). Determination of Loline Alkaloids and Mycelial Biomass in Endophyte-Infected Schedonorus pratensis by Near-Infrared Spectroscopy and Chemometrics. Microorganisms, 8(5), 776. https://doi.org/10.3390/microorganisms8050776
Forte, F. P., Schmid, J., Dijkwel, P. P., Nagy, I., Hume, D. E., Johnson, R. D., Simpson, W. R., Monk, S. M., Zhang, N., Sehrish, T., & Asp, T. (2020). Fungal Endophyte Colonization Patterns Alter Over Time in the Novel Association Between Lolium perenne and Epichloë Endophyte AR37. Frontiers in Plant Science, 11. https://doi.org/10.3389/fpls.2020.570026
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Bailey, M. H., Meyerson, W. U., Dursi, L. J., Wang, L.-B., Dong, G., Liang, W.-W., Weerasinghe, A., Li, S., Li, Y., Kelso, S., Akbani, R., Anur, P., Bailey, M. H., Buchanan, A., Chiotti, K., Covington, K., Creason, A., Ding, L., … Ellrott, K. (2020). Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-18151-y
Li, C. H., Prokopec, S. D., Sun, R. X., Yousif, F., Schmitz, N., Al-Shahrour, F., Atwal, G., Bailey, P. J., Biankin, A. V., Boutros, P. C., Campbell, P. J., Chang, D. K., Cooke, S. L., Deshpande, V., Faltas, B. M., Faquin, W. C., Garraway, L., Getz, G., … Grimmond, S. M. (2020). Sex differences in oncogenic mutational processes. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-17359-2
Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T.-K., … McIntosh, A. M. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications, 11(1). doi:10.1038/s41467-020-16022-0
Reyna, M. A., Haan, D., Paczkowska, M., Verbeke, L. P. C., … Vazquez, M. (2020). Pathway and network analysis of more than 2500 whole cancer genomes. Nature Communications, 11(1). doi:10.1038/s41467-020-14367-0
Rubanova, Y., Shi, R., Harrigan, C. F., Li, R., Wintersinger, J., Sahin, N., Deshwar, A. G., Dentro, S. C., Leshchiner, I., Gerstung, M., Jolly, C., Haase, K., Tarabichi, M., Wintersinger, J., Deshwar, A. G., Yu, K., Gonzalez, S., Rubanova, Y., … Macintyre, G. (2020). Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-14352-7
Cmero, M., Yuan, K., Ong, C. S., Schröder, J., Adams, D. J., Anur, P., Beroukhim, R., Boutros, P. C., Bowtell, D. D. L., Campbell, P. J., Cao, S., Christie, E. L., Cun, Y., Dawson, K. J., Demeulemeester, J., Dentro, S. C., Deshwar, A. G., Donmez, N., … Drews, R. M. (2020). Inferring structural variant cancer cell fraction. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-14351-8
Shah, N., Wakabayashi, T., Kawamura, Y., Skovbjerg, C. K., Wang, M.-Z., Mustamin, Y., … Andersen, S. U. (2020). Extreme genetic signatures of local adaptation during Lotus japonicus colonization of Japan. Nature Communications, 11(1). doi:10.1038/s41467-019-14213-y
Bhandari, V., Li, C. H., Bristow, R. G., Boutros, P. C., Aaltonen, L. A., Abascal, F., Abeshouse, A., Aburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S.-M., Aikata, H., Akbani, R., Akdemir, K. C., Al-Ahmadie, H., Al-Sedairy, S. T., Al-Shahrour, F., … Alawi, M. (2020). Divergent mutational processes distinguish hypoxic and normoxic tumours. Nature Communications, 11(1). https://doi.org/10.1038/s41467-019-14052-x
Paczkowska, M., Barenboim, J., Sintupisut, N., Fox, N. S., … Zhu, H. (2020). Integrative pathway enrichment analysis of multivariate omics data. Nature Communications, 11(1). doi:10.1038/s41467-019-13983-9
Shuai, S., Gallinger, S., & Stein, L. (2020). Combined burden and functional impact tests for cancer driver discovery using DriverPower. Nature Communications, 11(1). doi:10.1038/s41467-019-13929-1
Zhang, Y., Chen, F., Fonseca, N. A., He, Y., … Fujita, M. (2020). High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nature Communications, 11(1). doi:10.1038/s41467-019-13885-w
Jiao, W., Atwal, G., Polak, P., Karlic, R., Cuppen, E., Al-Shahrour, F., Atwal, G., Bailey, P. J., Biankin, A. V., Boutros, P. C., Campbell, P. J., Chang, D. K., Cooke, S. L., Deshpande, V., Faltas, B. M., Faquin, W. C., Garraway, L., Getz, G., … Grimmond, S. M. (2020). A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature Communications, 11(1). https://doi.org/10.1038/s41467-019-13825-8
Sieverling, L., Hong, C., Koser, S. D., Ginsbach, P., Kleinheinz, K., Hutter, B., Braun, D. M., Cortés-Ciriano, I., Xi, R., Kabbe, R., Park, P. J., Eils, R., Schlesner, M., Akdemir, K. C., Alvarez, E. G., Baez-Ortega, A., Beroukhim, R., Boutros, P. C., … Bowtell, D. D. L. (2020). Genomic footprints of activated telomere maintenance mechanisms in cancer. Nature Communications, 11(1). https://doi.org/10.1038/s41467-019-13824-9
Frandsen, P., Fontsere, C., Nielsen, S. V., Hanghøj, K., Castejon-Fernandez, N., Lizano, E., … Hvilsom, C. (2020). Targeted conservation genetics of the endangered chimpanzee. Heredity. doi:10.1038/s41437-020-0313-0
Athanasiadis, G., Speed, D., Andersen, M. K., Appel, E. V. R., Grarup, N., Brandslund, I., Jørgensen, M. E., Larsen, C. V. L., Bjerregaard, P., Hansen, T., & Albrechtsen, A. (2020). Estimating narrow-sense heritability using family data from admixed populations. Heredity, 124(6), 751–762. https://doi.org/10.1038/s41437-020-0311-2
Nudel, R., Benros, M. E., Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, M., Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, T., Rasmussen, S., & Thompson, W. K. (2020). Correction: Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorder. European Journal of Human Genetics, 29(8), 1316–1316. https://doi.org/10.1038/s41431-020-00772-y
Lall, G. M., Larmuseau, M. H. D., Wetton, J. H., Batini, C., Hallast, P., Huszar, T. I., Zadik, D., Aase, S., Baker, T., Balaresque, P., Bodmer, W., Børglum, A. D., de Knijff, P., Dunn, H., Harding, S. E., Løvvik, H., Dupuy, B. M., Pamjav, H., Tillmar, A. O., … Jobling, M. A. (2020). Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain. European Journal of Human Genetics, 29(3), 512–523. https://doi.org/10.1038/s41431-020-00747-z
Østergaard, S. D., Trabjerg, B. B., Als, T. D., Climent, C. A., Privé, F., Vilhjálmsson, B. J., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, M., Werge, T., Demontis, D., Mortensen, P. B., Børglum, A. D., Mors, O., & Agerbo, E. (2020). Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder. Translational Psychiatry, 10(1). https://doi.org/10.1038/s41398-020-01019-6
Rajkumar, A. P., Qvist, P., Donskov, J. G., Lazarus, R., Pallesen, J., Nava, N., Winther, G., Liebenberg, N., Cour, S. H. la, Paternoster, V., Fryland, T., Palmfeldt, J., Fejgin, K., Mørk, A., Nyegaard, M., Pakkenberg, B., Didriksen, M., Nyengaard, J. R., Wegener, G., … Børglum, A. D. (2020). Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice. Translational Psychiatry, 10(1). https://doi.org/10.1038/s41398-020-00914-2
Ernst, M., Rogers, S., Lausten-Thomsen, U., Björkbom, A., Laursen, S. S., Courraud, J., Børglum, A., Nordentoft, M., Werge, T., Mortensen, P. B., Hougaard, D. M., & Cohen, A. S. (2020). Gestational age-dependent development of the neonatal metabolome. Pediatric Research, 89(6), 1396–1404. https://doi.org/10.1038/s41390-020-01149-z
Rovira, P., Demontis, D., Sánchez-Mora, C., Zayats, T., Klein, M., … Pagerols, M. (2020). Shared genetic background between children and adults with attention deficit/hyperactivity disorder. Neuropsychopharmacology. doi:10.1038/s41386-020-0664-5
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., … Breen, G. (2020). Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry. doi:10.1038/s41380-020-0779-4
Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., … Tekola-Ayele, F. (2020). Association of polygenic score for major depression with response to lithium in patients with bipolar disorder. Molecular Psychiatry. doi:10.1038/s41380-020-0689-5
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., … Breen, G. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry. doi:10.1038/s41380-019-0546-6
Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T.-K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., … Agrawal, A. (2020). A large-scale genome-wide association study meta-analysis of cannabis use disorder. The Lancet Psychiatry, 7(12), 1032–1045. https://doi.org/10.1016/s2215-0366(20)30339-4
Anderson, F. L., Knudsen, M. L., Ahmad, C. S., & Popkin, C. A. (2020). Current Trends and Impact of Early Sports Specialization in the Throwing Athlete. Orthopedic Clinics of North America, 51(4), 517–525. https://doi.org/10.1016/j.ocl.2020.06.006
Schijven, D., Stevelink, R., McCormack, M., van Rheenen, W., Luykx, J. J., Koeleman, B. P. C., & Veldink, J. H. (2020). Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy. Neurobiology of Aging, 92, 153.e1-153.e5. https://doi.org/10.1016/j.neurobiolaging.2020.04.011
Kumar, S., Warrell, J., Li, S., McGillivray, P. D., Meyerson, W., Salichos, L., … Gerstein, M. B. (2020). Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences. Cell, 180(5), 915–927.e16. doi:10.1016/j.cell.2020.01.032
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J.-Y., … Klei, L. (2020). Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism. Cell. doi:10.1016/j.cell.2019.12.036
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Breen, G., Byrne, E. M., Forstner, A. J., … McQuillin, A. (2019). The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls. Biological Psychiatry. doi:10.1016/j.biopsych.2019.10.015
Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., … Baune, B. T. (2019). Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. Biological Psychiatry. doi:10.1016/j.biopsych.2019.06.031
Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, M., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B., & Agerbo, E. (2020). Genetic liability to major depression and risk of childhood asthma. Brain, Behavior, and Immunity, 89, 433–439. https://doi.org/10.1016/j.bbi.2020.07.030
Harrison, A. K., Knudsen, M. L., & Braman, J. P. (2020). Hemiarthroplasty and Total Shoulder Arthroplasty Conversion to Reverse Total Shoulder Arthroplasty. Current Reviews in Musculoskeletal Medicine, 13(4), 501–508. https://doi.org/10.1007/s12178-020-09649-5
Keyt, L. K., Tangtiphaiboontana, J., Turner, T. W., Dines, J. S., Knudsen, M. L., & Camp, C. L. (2020). Revision Medial Ulnar Collateral Ligament Reconstruction in Baseball Pitchers: Review of Epidemiology, Surgical Techniques, and Outcomes. Current Reviews in Musculoskeletal Medicine, 13(3), 361–368. doi:10.1007/s12178-020-09619-x
Thomsen, A. H., Villesen, P., Brink, O., Leth, P. M., & Hougen, H. P. (2020). Improved medical treatment could explain a decrease in homicides with a single stab wound. Forensic Science, Medicine and Pathology. doi:10.1007/s12024-020-00246-z
Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J., Børglum, A. D., … Benros, M. E. (2020). A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness. Human Genetics, 139(5), 593–604. doi:10.1007/s00439-020-02140-8
Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M., Børglum, A. D., Nordentoft, M., Werge, T., Christiansen, M., Schmiegelow, K., Juhler, M., Mortensen, P. B., Hougaard, D. M., & Bybjerg-Grauholm, J. (2020). Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci. Child’s Nervous System, 37(3), 819–830. https://doi.org/10.1007/s00381-020-04946-3
Cheng, J. Y., & Mailund, T. (2020). Ancestral Population Genomics with Jocx, a Coalescent Hidden Markov Model. Statistical Population Genomics, 167–189. doi:10.1007/978-1-0716-0199-0_8
Castellano, D., & Munch, K. (2020). Population Genomics in the Great Apes. Statistical Population Genomics, 453–463. doi:10.1007/978-1-0716-0199-0_19
Malinowska, M., Nagy, I., Wagemaker, C. A. M., Ruud, A. K., Svane, S. F., Thorup‐Kristensen, K., Jensen, C. S., Eriksen, B., Krusell, L., Jahoor, A., Jensen, J., Eriksen, L. B., & Asp, T. (2020). The cytosine methylation landscape of spring barley revealed by a new reduced representation bisulfite sequencing pipeline, WellMeth. The Plant Genome, 13(3). Portico. https://doi.org/10.1002/tpg2.20049
Terkelsen, T., Larsen, O. H., Vang, S., Jensen, U. B., & Wikman, F. (2020). Deleterious mis‐splicing of STK11 caused by a novel single‐nucleotide substitution in the 3′ polypyrimidine tract of intron five. Molecular Genetics & Genomic Medicine, 8(9). Portico. https://doi.org/10.1002/mgg3.1381
Nielsen, M. M., Trolle, C., Vang, S., Hornshøj, H., Skakkebæk, A., Hedegaard, J., Nordentoft, I., Pedersen, J. S., & Gravholt, C. H. (2020). Epigenetic and transcriptomic consequences of excess X‐chromosome material in 47, XXX syndrome—A comparison with Turner syndrome and 46, XX females. American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 184(2), 279–293. Portico. https://doi.org/10.1002/ajmg.c.31799

2019

(92 publications)

Chopra, A., Sagredo, S., Grossi, G., Andersen, E., & Simmel, F. (2019). Out-of-Plane Aptamer Functionalization of RNA Three-Helix Tiles. Nanomaterials, 9(4), 507. doi:10.3390/nano9040507
Liu, S., Aagaard, A., Bechsgaard, J., & Bilde, T. (2019). DNA Methylation Patterns in the Social Spider, Stegodyphus dumicola. Genes, 10(2), 137. doi:10.3390/genes10020137
Cagnano, G., Roulund, N., Jensen, C. S., Forte, F. P., Asp, T., & Leuchtmann, A. (2019). Large Scale Screening of Epichloë Endophytes Infecting Schedonorus pratensis and Other Forage Grasses Reveals a Relation Between Microsatellite-Based Haplotypes and Loline Alkaloid Levels. Frontiers in Plant Science, 10. doi:10.3389/fpls.2019.00765
Drange, O. K., Smeland, O. B., Shadrin, A. A., Finseth, P. I., Witoelar, A., & Frei, O. (2019). Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes. Frontiers in Neuroscience, 13. doi:10.3389/fnins.2019.00220
Herring, M. J., Knudsen, M. L., & Macalena, J. A. (2019). Open Reduction, Bone Grafting, and Internal Fixation of Osteochondritis Dissecans Lesion of the Knee. JBJS Essential Surgical Techniques, 9(3), e23. doi:10.2106/jbjs.st.18.00035
Bukowski, L., Chernomorchenko, A., Starnawska, A., Staunstrup, N., Qvist, P., & Børglum, A. (2019). Neuropsin in Mental Health. doi:10.20944/preprints201905.0360.v1
Castellano, D., Macià, M. C., Tataru, P., Bataillon, T., & Munch, K. (2019). Comparison of the Full Distribution of Fitness Effects of New Amino Acid Mutations Across Great Apes. Genetics, 213(3), 953–966. doi:10.1534/genetics.119.302494
Madsen, T., Świtnicki, M., Juul, M., & Pedersen, J. S. (2019). EBADIMEX: an empirical Bayes approach to detect joint differential expression and methylation and to classify samples. Statistical Applications in Genetics and Molecular Biology, 18(6). doi:10.1515/sagmb-2018-0050
Gruening, B., Sallou, O., Moreno, P., da Veiga Leprevost, F., Ménager, H., … Søndergaard, D. (2019). Recommendations for the packaging and containerizing of bioinformatics software. F1000Research, 7, 742. doi:10.12688/f1000research.15140.2
Christensen, E., Birkenkamp-Demtröder, K., Sethi, H., Shchegrova, S., Salari, R., Nordentoft, I., … Dyrskjøt, L. (2019). Early Detection of Metastatic Relapse and Monitoring of Therapeutic Efficacy by Ultra-Deep Sequencing of Plasma Cell-Free DNA in Patients With Urothelial Bladder Carcinoma. Journal of Clinical Oncology, 37(18), 1547–1557. doi:10.1200/jco.18.02052
Walker, J. A., Jordan, V. E., Storer, J. M., Steely, C. J., Gonzalez-Quiroga, P., … Batzer, M. A. (2019). Alu insertion polymorphisms shared by Papio baboons and Theropithecus gelada reveal an intertwined common ancestry. Mobile DNA, 10(1). doi:10.1186/s13100-019-0187-y
Johansen, A. F. B., Kassentoft, C. G., Knudsen, M., Laursen, M. B., Madsen, A. H., Iversen, L. H., … Andersen, C. L. (2019). Validation of computational determination of microsatellite status using whole exome sequencing data from colorectal cancer patients. BMC Cancer, 19(1). doi:10.1186/s12885-019-6227-7
Furtado, B. U., Nagy, I., Asp, T., Tyburski, J., Skorupa, M., Gołębiewski, M., … Hrynkiewicz, K. (2019). Transcriptome profiling and environmental linkage to salinity across Salicornia europaea vegetation. BMC Plant Biology, 19(1). doi:10.1186/s12870-019-2032-3
Bavafaye Haghighi, E., Knudsen, M., Elmedal Laursen, B., & Besenbacher, S. (2019). Hierarchical Classification of Cancers of Unknown Primary Using Multi-Omics Data. Cancer Informatics, 18, 117693511987216. doi:10.1177/1176935119872163
Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., … Starnawska, A. (2019). GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. American Journal of Psychiatry, 176(8), 651–660. doi:10.1176/appi.ajp.2019.18080957
Klein, M., Walters, R. K., Demontis, D., Stein, J. L., Hibar, D. P., Adams, H. H., … Franke, B. (2019). Genetic Markers of ADHD-Related Variations in Intracranial Volume. American Journal of Psychiatry, 176(3), 228–238. doi:10.1176/appi.ajp.2018.18020149
Nielsen, S. S. F., Weiss, S., Nazipi, S., Marshall, I. P. G., Bilde, T., & Schramm, A. (2019). Draft Genome Sequence of Bacillus subtilis SB-14, an Antimicrobially Active Isolate from Namibian Social Spiders (Stegodyphus dumicola). Microbiology Resource Announcements, 8(25). doi:10.1128/mra.00156-19
Rogers, J., Raveendran, M., Harris, R. A., Mailund, T., Leppälä, K., … Athanasiadis, G. (2019). The comparative genomics and complex population history ofPapiobaboons. Science Advances, 5(1), eaau6947. doi:10.1126/sciadv.aau6947
Mattingsdal, M., Jorde, P. E., Knutsen, H., Jentoft, S., Stenseth, N. C., Sodeland, M., … Blanco Gonzalez, E. (2019). Demographic history has shaped the strongly differentiated corkwing wrasse populations in Northern Europe. Molecular Ecology, 29(1), 160–171. doi:10.1111/mec.15310
Treur, J. L., Demontis, D., Smith, G. D., Sallis, H., Richardson, T. G., Wiers, R. W., … Munafò, M. R. (2019). Investigating causality between liability to ADHD and substance use, and liability to substance use and ADHD risk, using Mendelian randomization. Addiction Biology. doi:10.1111/adb.12849
Speed, D., Hemani, G., Speed, M. S., Børglum, A. D., & Østergaard, S. D. (2019). Investigating the causal relationship between neuroticism and depression via Mendelian randomization. Acta Psychiatrica Scandinavica, 139(4), 395–397. doi:10.1111/acps.13009
Thomsen, A. H., Hougen, H. P., Villesen, P., Brink, O., & Leth, P. M. (2019). Sharp Force Homicide in Denmark 1992–2016. Journal of Forensic Sciences. doi:10.1111/1556-4029.14244
Griffiths, A. G., Moraga, R., Tausen, M., Gupta, V., Bilton, T. P., Campbell, M. A., … Andersen, S. U. (2019). Breaking Free: The Genomics of Allopolyploidy-Facilitated Niche Expansion in White Clover. The Plant Cell, 31(7), 1466–1487. doi:10.1105/tpc.18.00606
Refoyo-Martínez, A., da Fonseca, R. R., Halldórsdóttir, K., Árnason, E., Mailund, T., & Racimo, F. (2019). Identifying loci under positive selection in complex population histories. Genome Research, 29(9), 1506–1520. doi:10.1101/gr.246777.118
Jager, M., Blokzijl, F., Kuijk, E., Bertl, J., Vougioukalaki, M., Janssen, R., … Cuppen, E. (2019). Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer. Genome Research, 29(7), 1067–1077. doi:10.1101/gr.246223.118
Lescai, F., Grove, J., Satterstrom, F. K., Rees, E., Bybjerg-Grauholm, J., Als, T. D., … Børglum, A. D. (2019). Meta-analysis of Scandinavian Schizophrenia Exomes. doi:10.1101/836957
Demontis, D., Walters, R., Rajagopal, V. M., Waldman, I. D., Grove, J., … Als, T. D. (2019). Identification of risk variants and characterization of the polygenic architecture of disruptive behavior disorders in the context of ADHD. doi:10.1101/791160
Yang, Z., Wu, H., Lee, P. H., Tsetsos, F., Davis, L. K., Yu, D., … Paschou, P. (2019). Cross-disorder GWAS meta-analysis for Attention Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, Obsessive Compulsive Disorder, and Tourette Syndrome. doi:10.1101/770222
Zhou, H., Sealock, J. M., Sanchez-Roige, S., Clarke, T.-K., Levey, D., … Cheng, Z. (2019). Meta-analysis of problematic alcohol use in 435,563 individuals identifies 29 risk variants and yields insights into biology, pleiotropy and causality. doi:10.1101/738088
Klein, M., Singgih, E., van Rens, A., Demontis, D., Børglum, A. D., Mota, N. R., … Franke, B. (2019). Intellectual Disability-related genes increase ADHD risk and locomotor activity in Drosophila. doi:10.1101/725937
Liu, X., Nudel, R., Thompson, W. K., Appadurai, V., Schork, A. J., Buil, A., … Benros, M. E. (2019). Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders – findings from a Danish population-based study. doi:10.1101/699462
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Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D., & Østergaard, S. D. (2019). Investigating the Association Between Body Fat and Depression via Mendelian Randomization. doi:10.1101/539601
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Bechsgaard, J., Schou, M. F., Vanthournout, B., Hendrickx, F., Knudsen, B., Settepani, V., … Bilde, T. (2019). Evidence for Faster X Chromosome Evolution in Spiders. Molecular Biology and Evolution, 36(6), 1281–1293. doi:10.1093/molbev/msz074
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Castellano, D., Eyre-Walker, A., & Munch, K. (2019). Impact of Mutation Rate and Selection at Linked Sites on DNA Variation across the Genomes of Humans and Other Homininae. Genome Biology and Evolution, 12(1), 3550–3561. doi:10.1093/gbe/evz215
Sengupta, M. E., Hellström, M., Kariuki, H. C., Olsen, A., Thomsen, P. F., Mejer, H., … Vennervald, B. J. (2019). Environmental DNA for improved detection and environmental surveillance of schistosomiasis. Proceedings of the National Academy of Sciences, 116(18), 8931–8940. doi:10.1073/pnas.1815046116
Warrier, V., Toro, R., Won, H., Leblond, C. S., Cliquet, F., Delorme, R., … Baron-Cohen, S. (2019). Social and non-social autism symptoms and trait domains are genetically dissociable. Communications Biology, 2(1). doi:10.1038/s42003-019-0558-4
Lyskjær, I., Kronborg, C. S., Rasmussen, M. H., Sørensen, B. S., Demuth, C., Rosenkilde, M., … Andersen, C. L. (2019). Correlation between early dynamics in circulating tumour DNA and outcome from FOLFIRI treatment in metastatic colorectal cancer. Scientific Reports, 9(1). doi:10.1038/s41598-019-47708-1
Sarwar, M. B., Ahmad, Z., Rashid, B., Hassan, S., Gregersen, P. L., Leyva, M. D. la O., … Husnain, T. (2019). De novo assembly of Agave sisalana transcriptome in response to drought stress provides insight into the tolerance mechanisms. Scientific Reports, 9(1). doi:10.1038/s41598-018-35891-6
Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M., Lescai, F., … Daly, M. J. (2019). Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants. Nature Neuroscience, 22(12), 1961–1965. doi:10.1038/s41593-019-0527-8
Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., … Børglum, A. D. (2019). Genome-wide association study implicates CHRNA2 in cannabis use disorder. Nature Neuroscience, 22(7), 1066–1074. doi:10.1038/s41593-019-0416-1
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., … Werge, T. (2019). A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment. Nature Neuroscience, 22(3), 353–361. doi:10.1038/s41593-018-0320-0
Christensen, J. H., & Børglum, A. D. (2019). Modeling the cooperativity of schizophrenia risk genes. Nature Genetics, 51(10), 1434–1436. doi:10.1038/s41588-019-0508-6
Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., … Cameron, D. (2019). Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 51(7), 1193–1193. doi:10.1038/s41588-019-0450-7
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., … Wang, W. (2019). Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51(6), 1068–1068. doi:10.1038/s41588-019-0435-6
Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., … Coleman, J. R. I. (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51(5), 793–803. doi:10.1038/s41588-019-0397-8
Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., … Stefánsson, K. (2019). Roadmap for a precision-medicine initiative in the Nordic region. Nature Genetics, 51(6), 924–930. doi:10.1038/s41588-019-0391-1
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., … Wang, W. (2019). Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. Nature Genetics, 51(4), 659–674. doi:10.1038/s41588-019-0364-4
Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R. K., … Andreassen, O. A. (2019). Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics, 51(3), 431–444. doi:10.1038/s41588-019-0344-8
Besenbacher, S., Hvilsom, C., Marques-Bonet, T., Mailund, T., & Schierup, M. H. (2019). Author Correction: Direct estimation of mutations in great apes reconciles phylogenetic dating. Nature Ecology & Evolution, 3(5), 859–859. doi:10.1038/s41559-019-0898-y
Besenbacher, S., Hvilsom, C., Marques-Bonet, T., Mailund, T., & Schierup, M. H. (2019). Direct estimation of mutations in great apes reconciles phylogenetic dating. Nature Ecology & Evolution, 3(2), 286–292. doi:10.1038/s41559-018-0778-x
Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., … Gelernter, J. (2019). International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nature Communications, 10(1). doi:10.1038/s41467-019-12576-w
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., … Lin, F. T. J. (2019). Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration. Nature Communications, 10(1). doi:10.1038/s41467-019-11881-8
Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., … Binder, E. B. (2019). Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications, 10(1). doi:10.1038/s41467-019-10461-0
Kuderna, L. F. K., Lizano, E., Julià, E., Gomez-Garrido, J., Serres-Armero, A., Kuhlwilm, M., … Marques-Bonet, T. (2019). Selective single molecule sequencing and assembly of a human Y chromosome of African origin. Nature Communications, 10(1). doi:10.1038/s41467-018-07885-5
Nudel, R., Benros, M. E., Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., … Thompson, W. K. (2019). Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders. European Journal of Human Genetics, 27(9), 1445–1455. doi:10.1038/s41431-019-0402-9
Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., … Meltzer-Brody, S. (2019). Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders. Translational Psychiatry, 9(1). doi:10.1038/s41398-019-0629-9
Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., … Benros, M. E. (2019). A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population. Translational Psychiatry, 9(1). doi:10.1038/s41398-019-0622-3
Skogstrand, K., Hagen, C. M., Borbye-Lorenzen, N., Christiansen, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., … Hougaard, D. M. (2019). Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders. Translational Psychiatry, 9(1). doi:10.1038/s41398-019-0587-2
Pineda-Cirera, L., Shivalikanjli, A., Cabana-Domínguez, J., Demontis, D., Rajagopal, V. M., Børglum, A. D., … Fernàndez-Castillo, N. (2019). Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorder. Translational Psychiatry, 9(1). doi:10.1038/s41398-019-0574-7
Speed, M. S., Jefsen, O. H., Børglum, A. D., Speed, D., & Østergaard, S. D. (2019). Investigating the association between body fat and depression via Mendelian randomization. Translational Psychiatry, 9(1). doi:10.1038/s41398-019-0516-4
Verhoef, E., Demontis, D., Burgess, S., Shapland, C. Y., Dale, P. S., … St Pourcain, B. (2019). Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language. Translational Psychiatry, 9(1). doi:10.1038/s41398-018-0324-2
Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., … Friedrich, N. (2019). Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Molecular Psychiatry. doi:10.1038/s41380-019-0590-2
Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., … Eley, T. C. (2019). A major role for common genetic variation in anxiety disorders. Molecular Psychiatry. doi:10.1038/s41380-019-0559-1
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., … González, M. J. (2019). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry. doi:10.1038/s41380-019-0558-2
Hess, J. L., Tylee, D. S., Mattheisen, M., Børglum, A. D., … Als, T. D. (2019). A polygenic resilience score moderates the genetic risk for schizophrenia. Molecular Psychiatry. doi:10.1038/s41380-019-0463-8
Soler Artigas, M., Sánchez-Mora, C., Rovira, P., Richarte, V., Garcia-Martínez, I., … Ribasés, M. (2019). Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality. Molecular Psychiatry. doi:10.1038/s41380-018-0339-3
Hjorthøj, C., Uddin, M. J., Wimberley, T., Dalsgaard, S., Hougaard, D. M., Børglum, A., … Nordentoft, M. (2019). No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder. Psychological Medicine, 1–6. doi:10.1017/s0033291719003362
Gasse, C., Wimberley, T., Wang, Y., Mors, O., Børglum, A., Als, T. D., … Horsdal, H. T. (2019). Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia. Schizophrenia Research, 212, 79–85. doi:10.1016/j.schres.2019.08.008
Paternoster, V., Svanborg, M., Edhager, A. V., Rajkumar, A. P., Eickhardt, E. A., Pallesen, J., … Christensen, J. H. (2019). Brain proteome changes in female Brd1 mice unmask dendritic spine pathology and show enrichment for schizophrenia risk. Neurobiology of Disease, 124, 479–488. doi:10.1016/j.nbd.2018.12.011
Leduc-Galindo, D., Qvist, P., Tóth, A. E., Fryland, T., Nielsen, M. S., Børglum, A. D., & Christensen, J. H. (2019). The effect of hypoxia on ZEB1 expression in a mimetic system of the blood-brain barrier. Microvascular Research, 122, 131–135. doi:10.1016/j.mvr.2018.08.004
Thomsen, A. H., Leth, P. M., Hougen, H. P., Villesen, P., & Brink, O. (2019). Homicide in Denmark 1992–2016. Forensic Science International: Synergy, 1, 275–282. doi:10.1016/j.fsisyn.2019.07.001
Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., … Posthuma, D. (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell, 179(7), 1469–1482.e11. doi:10.1016/j.cell.2019.11.020
Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T.-K., Gibson, J., … Lawrie, S. M. (2019). Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(1), 91–100. doi:10.1016/j.bpsc.2018.07.006
Grinsted, L., Schou, M. F., Settepani, V., Holm, C., Bird, T. L., & Bilde, T. (2019). Prey to predator body size ratio in the evolution of cooperative hunting—a social spider test case. Development Genes and Evolution, 230(2), 173–184. doi:10.1007/s00427-019-00640-w
Besenbacher, S., Mailund, T., Vilhjálmsson, B. J., & Schierup, M. H. (2019). Association Mapping and Disease: Evolutionary Perspectives. Evolutionary Genomics, 533–553. doi:10.1007/978-1-4939-9074-0_17
Strand, S. H., Bavafaye‐Haghighi, E., Kristensen, H., Rasmussen, A. K., Hoyer, S., Borre, M., … Sorensen, K. D. (2019). A novel combined miRNA and methylation marker panel (miMe) for prediction of prostate cancer outcome after radical prostatectomy. International Journal of Cancer, 145(12), 3445–3452. doi:10.1002/ijc.32427
Blanco Gonzalez, E., Espeland, S. H., Jentoft, S., Hansen, M. M., Robalo, J. I., Stenseth, N. C., & Jorde, P. E. (2019). Interbreeding between local and translocated populations of a cleaner fish in an experimental mesocosm predicts risk of disrupted local adaptation. Ecology and Evolution. doi:10.1002/ece3.5246
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., … Walters, J. (2019). Population‐based identity‐by‐descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180(3), 223–231. doi:10.1002/ajmg.b.32716
Trzaskowski, M., Mehta, D., Peyrot, W. J., Hawkes, D., Davies, D., … Howard, D. M. (2019). Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 180(6), 439–447. doi:10.1002/ajmg.b.32713
Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., … Mors, O. (2019). Genetic Variants Associated With Anxiety and Stress-Related Disorders. JAMA Psychiatry, 76(9), 924. doi:10.1001/jamapsychiatry.2019.1119
Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., … Bybjerg-Grauholm, J. (2019). Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population. JAMA Psychiatry, 76(5), 516. doi:10.1001/jamapsychiatry.2018.4166
Reinert, T., Henriksen, T. V., Christensen, E., Sharma, S., Salari, R., Sethi, H., … Lindbjerg Andersen, C. (2019). Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer. JAMA Oncology, 5(8), 1124. doi:10.1001/jamaoncol.2019.0528
Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., … Pedersen, C. B. (2019). Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia. JAMA Network Open, 2(11), e1914401. doi:10.1001/jamanetworkopen.2019.14401

2018

(78 publications)

Sverrisdóttir, E., Sundmark, E. H. R., Johnsen, H. Ø., Kirk, H. G., Asp, T., Janss, L., … Nielsen, K. L. (2018). The Value of Expanding the Training Population to Improve Genomic Selection Models in Tetraploid Potato. Frontiers in Plant Science, 9. doi:10.3389/fpls.2018.01118
Cericola, F., Lenk, I., Fè, D., Byrne, S., Jensen, C. S., Pedersen, M. G., … Janss, L. (2018). Optimized Use of Low-Depth Genotyping-by-Sequencing for Genomic Prediction Among Multi-Parental Family Pools and Single Plants in Perennial Ryegrass (Lolium perenne L.). Frontiers in Plant Science, 9. doi:10.3389/fpls.2018.00369
Ernst, E. H., Nielsen, J., Ipsen, M. B., Villesen, P., & Lykke-Hartmann, K. (2018). Transcriptome Analysis of Long Non-coding RNAs and Genes Encoding Paraspeckle Proteins During Human Ovarian Follicle Development. Frontiers in Cell and Developmental Biology, 6. doi:10.3389/fcell.2018.00078
Lucotte, E. A., Skov, L., Jensen, J. M., Coll Macià, M., Munch, K., & Schierup, M. H. (2018). Dynamic Copy Number Evolution of X- and Y-Linked Ampliconic Genes in Human Populations. Genetics, genetics.300826.2018. doi:10.1534/genetics.118.300826
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., … Christiansen, M. (2018). Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes. PLOS ONE, 13(12), e0208829. doi:10.1371/journal.pone.0208829
Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., … Christiansen, M. (2018). Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease. PLOS ONE, 13(12), e0208828. doi:10.1371/journal.pone.0208828
Skov, L., Hui, R., Shchur, V., Hobolth, A., Scally, A., Schierup, M. H., & Durbin, R. (2018). Detecting archaic introgression using an unadmixed outgroup. PLOS Genetics, 14(9), e1007641. doi:10.1371/journal.pgen.1007641
Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., … Mill, J. (2018). Elevated polygenic burden for autism is associated with differential DNA methylation at birth. Genome Medicine, 10(1). doi:10.1186/s13073-018-0527-4
Nielsen, M. M., Tataru, P., Madsen, T., Hobolth, A., & Pedersen, J. S. (2018). Regmex: a statistical tool for exploring motifs in ranked sequence lists from genomics experiments. Algorithms for Molecular Biology, 13(1). doi:10.1186/s13015-018-0135-2
Cai, Z., Villumsen, T. M., Asp, T., Guldbrandtsen, B., Sahana, G., & Lund, M. S. (2018). SNP markers associated with body size and pelt length in American mink (Neovison vison). BMC Genetics, 19(1). doi:10.1186/s12863-018-0688-6
Liu, S., Feuerstein, U., Luesink, W., Schulze, S., Asp, T., Studer, B., … Dehmer, K. J. (2018). DArT, SNP, and SSR analyses of genetic diversity in Lolium perenne L. using bulk sampling. BMC Genetics, 19(1). doi:10.1186/s12863-017-0589-0
Matey-Hernandez, M. L., Brunak, S., & Izarzugaza, J. M. G. (2018). Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios. BMC Bioinformatics, 19(1). doi:10.1186/s12859-018-2239-6
Bertl, J., Guo, Q., Juul, M., Besenbacher, S., Nielsen, M. M., Hornshøj, H., … Hobolth, A. (2018). A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data. BMC Bioinformatics, 19(1). doi:10.1186/s12859-018-2141-2
Ludvigsen, M., Bjerregård Pedersen, M., Lystlund Lauridsen, K., Svenstrup Poulsen, T., Hamilton-Dutoit, S. J., Besenbacher, S., … Honoré, B. (2018). Proteomic profiling identifies outcome-predictive markers in patients with peripheral T-cell lymphoma, not otherwise specified. Blood Advances, 2(19), 2533–2542. doi:10.1182/bloodadvances.2018019893
Lindahl, L. M., Besenbacher, S., Rittig, A. H., Celis, P., Willerslev-Olsen, A., Gjerdrum, L. M. R., … Iversen, L. (2018). Prognostic miRNA classifier in early-stage mycosis fungoides: development and validation in a Danish nationwide study. Blood, 131(7), 759–770. doi:10.1182/blood-2017-06-788950
Sullivan, P. F., Agrawal, A., Bulik, C. M., Andreassen, O. A., Børglum, A. D., … Breen, G. (2018). Psychiatric Genomics: An Update and an Agenda. American Journal of Psychiatry, 175(1), 15–27. doi:10.1176/appi.ajp.2017.17030283
Murra, M., Lützen, L., Barut, A., Zbinden, R., Lund, M., Villesen, P., & Nørskov-Lauritsen, N. (2018). Whole-Genome Sequencing ofAggregatibacterSpecies Isolated from Human Clinical Specimens and Description ofAggregatibacter kilianiisp. nov. Journal of Clinical Microbiology, 56(7). doi:10.1128/jcm.00053-18
Gandal, M. J., Haney, J. R., Parikshak, N. N., Leppa, V., Ramaswami, G., … Hartl, C. (2018). Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science, 359(6376), 693–697. doi:10.1126/science.aad6469
Liu, S., Ferchaud, A.-L., Grønkjaer, P., Nygaard, R., & Hansen, M. M. (2018). Genomic parallelism and lack thereof in contrasting systems of three-spined sticklebacks. Molecular Ecology, 27(23), 4725–4743. doi:10.1111/mec.14782
Ghislandi, P. G., Pekár, S., Matzke, M., Schulte-Döinghaus, S., Bilde, T., & Tuni, C. (2018). Resource availability, mating opportunity and sexual selection intensity influence the expression of male alternative reproductive tactics. Journal of Evolutionary Biology, 31(7), 1035–1046. doi:10.1111/jeb.13284
Shah, N., Wakabayashi, T., Kawamura, Y., Skovbjerg, C. K., Wang, M.-Z., Mustamin, Y., … Andersen, S. U. (2018). Extreme genetic signatures of local adaptation during plant colonization. doi:10.1101/485789
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J.-Y., … Klei, L. (2018). Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism. doi:10.1101/484113
Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C.-Y., Choi, K. W., … Logue, M. W. (2018). Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways. doi:10.1101/458562
Refoyo-Martínez, A., da Fonseca, R. R., Halldórsdóttir, K., Árnason, E., Mailund, T., & Racimo, F. (2018). Identifying loci under positive selection in complex population histories. doi:10.1101/453092
Castellano, D., Eyre-Walker, A., & Munch, K. (2018). Impact of mutation rate and selection at linked sites on fine-scale DNA variation across the homininae genome. doi:10.1101/452201
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., … Lin, F. T. J. (2018). Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration. doi:10.1101/423897
Speed, D., Hemani, G., Speed, M. S., Børglum, A. D., & Østergaard, S. D. (2018). Does Neuroticism Cause Depression? A Mendelian Randomization Study. doi:10.1101/420703
Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Fanous, A. H., … Stahl, E. A. (2018). Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores. doi:10.1101/416008
Pineda-Cirera, L., Shivalikanjli, A., Cabana-Domínguez, J., Demontis, D., Rajagopal, V. M., Børglum, A. D., … Fernàndez-Castillo, N. (2018). Exploring Genetic Variation that Influences Brain Methylation in Attention-Deficit/Hyperactivity Disorder. doi:10.1101/413005
Madsen, T., Świtnicki, M., Juul, M., & Pedersen, J. S. (2018). EBADIMEX: An empirical Bayes approach to detect joint differential expression and methylation and to classify samples. doi:10.1101/401232
Reyna, M. A., Haan, D., Paczkowska, M., Verbeke, L. P. C., Vazquez, M., … Kahraman, A. (2018). Pathway and network analysis of more than 2,500 whole cancer genomes. doi:10.1101/385294
Kuderna, L. F. K., Lizano, E., Julià, E., Gomez-Garrido, J., Serres-Armero, A., Kuhlwilm, M., … Marques-Bonet, T. (2018). Selective single molecule sequencing and assembly of a human Y chromosome of African origin. doi:10.1101/342667
Besenbacher, S., Hvilsom, C., Marques-Bonet, T., Mailund, T., & Schierup, M. H. (2018). Direct estimation of mutations in great apes reveals significant recent human slowdown in the yearly mutation rate. doi:10.1101/287821
Skov, L., Hui, R., Hobolth, A., Scally, A., Schierup, M. H., & Durbin, R. (2018). Detecting archaic introgression without archaic reference genomes. doi:10.1101/283606
Kumar, S., Warrell, J., Li, S., McGillivray, P. D., Meyerson, W., Salichos, L., … Gerstein, M. B. (2018). Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences. doi:10.1101/280446
Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M., Lescai, F., … Demontis, D. (2018). ASD and ADHD have a similar burden of rare protein-truncating variants. doi:10.1101/277707
Verhoef, E., Demontis, D., Burgess, S., Shapland, C. Y., Dale, P. S., … Okbay, A. (2018). Disentangling genetically confounded polygenic associations between Attention-Deficit/Hyperactivity Disorder, literacy and language. doi:10.1101/276527
Meier, S. M., Trontti, K., Als, T. D., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., … Mors, O. (2018). Genome-wide Association Study of Anxiety and Stress-related Disorders in the iPSYCH Cohort. doi:10.1101/263855
Rajkumar, A. P., Qvist, P., Larsen, S. H., Lazarus, R., Pallesen, J., Nava, N., … Børglum, A. D. (2018). The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders. doi:10.1101/257170
Vanthournout, B., Busck, M. M., Bechsgaard, J., Hendrickx, F., Schramm, A., & Bilde, T. (2018). Male spiders control offspring sex ratio through greater production of female-determining sperm. Proceedings of the Royal Society B: Biological Sciences, 285(1875), 20172887. doi:10.1098/rspb.2017.2887
Veeckman, E., Van Glabeke, S., Haegeman, A., Muylle, H., van Parijs, F. R. D., Byrne, S. L., … Ruttink, T. (2018). Overcoming challenges in variant calling: exploring sequence diversity in candidate genes for plant development in perennial ryegrass (Lolium perenne). DNA Research, 26(1), 1–12. doi:10.1093/dnares/dsy033
Juul, M., Madsen, T., Guo, Q., Bertl, J., Hobolth, A., Kellis, M., & Pedersen, J. S. (2018). ncdDetect2: improved models of the site-specific mutation rate in cancer and driver detection with robust significance evaluation. Bioinformatics, 35(2), 189–199. doi:10.1093/bioinformatics/bty511
Palkopoulou, E., Lipson, M., Mallick, S., Nielsen, S., Rohland, N., Baleka, S., … Reich, D. (2018). A comprehensive genomic history of extinct and living elephants. Proceedings of the National Academy of Sciences, 115(11), E2566–E2574. doi:10.1073/pnas.1720554115
De Jong, S., Diniz, M. J. A., Saloma, A., Gadelha, A., Santoro, M. L., … Breen, G. (2018). Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Communications Biology, 1(1). doi:10.1038/s42003-018-0155-y
Eyles, D. W., Trzaskowski, M., Vinkhuyzen, A. A. E., Mattheisen, M., Meier, S., Gooch, H., … McGrath, J. J. (2018). The association between neonatal vitamin D status and risk of schizophrenia. Scientific Reports, 8(1). doi:10.1038/s41598-018-35418-z
Qvist, P., Eskildsen, S. F., Hansen, B., Baragji, M., Ringgaard, S., Roovers, J., … Christensen, J. H. (2018). Brain volumetric alterations accompanied with loss of striatal medium-sized spiny neurons and cortical parvalbumin expressing interneurons in Brd1+/− mice. Scientific Reports, 8(1). doi:10.1038/s41598-018-34729-5
Skakkebæk, A., Nielsen, M. M., Trolle, C., Vang, S., Hornshøj, H., Hedegaard, J., … Gravholt, C. H. (2018). DNA hypermethylation and differential gene expression associated with Klinefelter syndrome. Scientific Reports, 8(1). doi:10.1038/s41598-018-31780-0
Majer, M., Holm, C., Lubin, Y., & Bilde, T. (2018). Cooperative foraging expands dietary niche but does not offset intra-group competition for resources in social spiders. Scientific Reports, 8(1). doi:10.1038/s41598-018-30199-x
Ni, G., Gratten, J., Wray, N. R., & Lee, S. H. (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports, 8(1). doi:10.1038/s41598-018-28160-z
Christensen, E., Nordentoft, I., Vang, S., Birkenkamp-Demtröder, K., Jensen, J. B., Agerbæk, M., … Dyrskjøt, L. (2018). Optimized targeted sequencing of cell-free plasma DNA from bladder cancer patients. Scientific Reports, 8(1). doi:10.1038/s41598-018-20282-8
Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., … Bybjerg-Grauholm, J. (2018). Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics, 51(1), 63–75. doi:10.1038/s41588-018-0269-7
Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., … Air, T. M. (2018). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics, 50(5), 668–681. doi:10.1038/s41588-018-0090-3
Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., … Cameron, D. (2018). Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics, 50(3), 381–389. doi:10.1038/s41588-018-0059-2
Hornshøj, H., Nielsen, M. M., Sinnott-Armstrong, N. A., Świtnicki, M. P., Juul, M., Madsen, T., … Pedersen, J. S. (2018). Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival. Npj Genomic Medicine, 3(1). doi:10.1038/s41525-017-0040-5
Olagnier, D., Brandtoft, A. M., Gunderstofte, C., Villadsen, N. L., Krapp, C., Thielke, A. L., … Holm, C. K. (2018). Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming. Nature Communications, 9(1). doi:10.1038/s41467-018-05861-7
Jepsen, M. D. E., Sparvath, S. M., Nielsen, T. B., Langvad, A. H., Grossi, G., Gothelf, K. V., & Andersen, E. S. (2018). Publisher Correction: Development of a genetically encodable FRET system using fluorescent RNA aptamers. Nature Communications, 9(1). doi:10.1038/s41467-018-03075-5
Jepsen, M. D. E., Sparvath, S. M., Nielsen, T. B., Langvad, A. H., Grossi, G., Gothelf, K. V., & Andersen, E. S. (2018). Development of a genetically encodable FRET system using fluorescent RNA aptamers. Nature Communications, 9(1). doi:10.1038/s41467-017-02435-x
Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., … Almstrup, K. (2018). Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells. Cell Death & Disease, 9(6). doi:10.1038/s41419-018-0671-1
Schmidt, L., Møller, M., Haldrup, C., Strand, S. H., Vang, S., Hedegaard, J., … Sørensen, K. D. (2018). Exploring the transcriptome of hormone-naive multifocal prostate cancer and matched lymph node metastases. British Journal of Cancer, 119(12), 1527–1537. doi:10.1038/s41416-018-0321-5
Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., … Reichenberg, A. (2018). Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis. Translational Psychiatry, 8(1). doi:10.1038/s41398-018-0229-0
Warrier, V., Toro, R., Chakrabarti, B., Børglum, A. D., … Grove, J. (2018). Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa. Translational Psychiatry, 8(1). doi:10.1038/s41398-017-0082-6
Erlangsen, A., Appadurai, V., Wang, Y., Turecki, G., Mors, O., Werge, T., … Agerbo, E. (2018). Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study. Molecular Psychiatry. doi:10.1038/s41380-018-0218-y
Hauberg, M. E., Fullard, J. F., Zhu, L., Cohain, A. T., Giambartolomei, C., … Roussos, P. (2018). Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls. Molecular Psychiatry, 24(11), 1685–1695. doi:10.1038/s41380-018-0059-8
Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., … Werge, T. (2018). Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study. The Lancet Psychiatry, 5(7), 573–580. doi:10.1016/s2215-0366(18)30168-8
Mattingsdal, M., Jentoft, S., Tørresen, O. K., Knutsen, H., Hansen, M. M., Robalo, J. I., … Gonzalez, E. B. (2018). A continuous genome assembly of the corkwing wrasse (Symphodus melops). Genomics, 110(6), 399–403. doi:10.1016/j.ygeno.2018.04.009
Dammark, K. B., Ferchaud, A.-L., Hansen, M. M., & Sørensen, J. G. (2018). Heat tolerance and gene expression responses to heat stress in threespine sticklebacks from ecologically divergent environments. Journal of Thermal Biology, 75, 88–96. doi:10.1016/j.jtherbio.2018.06.003
Paternoster, V., Rajkumar, A. P., Nyengaard, J. R., Børglum, A. D., Grove, J., & Christensen, J. H. (2018). The importance of data structure in statistical analysis of dendritic spine morphology. Journal of Neuroscience Methods, 296, 93–98. doi:10.1016/j.jneumeth.2017.12.022
Stride Nielsen, L., Villesen, P., & Lindholst, C. (2018). Stability of amphetamine impurity profiles during 12 months of storage. Forensic Science International, 290, 129–136. doi:10.1016/j.forsciint.2018.06.039
Birkenkamp-Demtröder, K., Christensen, E., Nordentoft, I., Knudsen, M., Taber, A., Høyer, S., … Dyrskjøt, L. (2018). Monitoring Treatment Response and Metastatic Relapse in Advanced Bladder Cancer by Liquid Biopsy Analysis. European Urology, 73(4), 535–540. doi:10.1016/j.eururo.2017.09.011
Jacobsen, K. M., Villadsen, N. L., Tørring, T., Nielsen, C. B., Salomón, T., Nielsen, M. M., … Poulsen, T. B. (2018). APD-Containing Cyclolipodepsipeptides Target Mitochondrial Function in Hypoxic Cancer Cells. Cell Chemical Biology, 25(11), 1337–1349.e12. doi:10.1016/j.chembiol.2018.07.010
Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., … Loohuis, L. M. O. (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell, 173(7), 1705–1715.e16. doi:10.1016/j.cell.2018.05.046
Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., … Lichtenstein, P. (2018). A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder. Biological Psychiatry, 83(12), 1044–1053. doi:10.1016/j.biopsych.2017.11.026
Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., … Nivard, M. G. (2018). Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium. Biological Psychiatry, 84(2), 138–147. doi:10.1016/j.biopsych.2017.09.009
Ganna, A., Satterstrom, F. K., Zekavat, S. M., Das, I., Kurki, M. I., Churchhouse, C., … Neale, B. M. (2018). Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum. The American Journal of Human Genetics, 102(6), 1204–1211. doi:10.1016/j.ajhg.2018.05.002
Ni, G., Moser, G., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., … Holmans, P. A. (2018). Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood. The American Journal of Human Genetics, 102(6), 1185–1194. doi:10.1016/j.ajhg.2018.03.021
Knorst, V., Byrne, S., Yates, S., Asp, T., Widmer, F., Studer, B., & Kölliker, R. (2018). Pooled DNA sequencing to identify SNPs associated with a major QTL for bacterial wilt resistance in Italian ryegrass (Lolium multiflorum Lam.). Theoretical and Applied Genetics, 132(4), 947–958. doi:10.1007/s00122-018-3250-z
Fonseca, B. D., Lahr, R. M., Damgaard, C. K., Alain, T., & Berman, A. J. (2018). LARP1 on TOP of ribosome production. Wiley Interdisciplinary Reviews: RNA, 9(5), e1480. doi:10.1002/wrna.1480
Høiberg, H. C., Sparvath, S. M., Andersen, V. L., Kjems, J., & Andersen, E. S. (2018). An RNA Origami Octahedron with Intrinsic siRNAs for Potent Gene Knockdown. Biotechnology Journal, 14(1), 1700634. doi:10.1002/biot.201700634

2017

(76 publications)

Juul, M., Bertl, J., Guo, Q., Nielsen, M. M., Świtnicki, M., Hornshøj, H., … Pedersen, J. S. (2017). Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate. eLife, 6. doi:10.7554/elife.21778
Starnawska, A., Tan, Q., McGue, M., Mors, O., Børglum, A. D., Christensen, K., … Christiansen, L. (2017). Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins. Frontiers in Aging Neuroscience, 9. doi:10.3389/fnagi.2017.00413
Bechsgaard, J., Jorgensen, T. H., & Schierup, M. H. (2017). Evidence for Adaptive Introgression of Disease Resistance Genes Among Closely Related Arabidopsis Species. G3: Genes|Genomes|Genetics, 7(8), 2677–2683. doi:10.1534/g3.117.043984
Søndergaard, D., Nielsen, S., Pedersen, C. N. S., & Besenbacher, S. (2017). Prediction of Primary Tumors in Cancers of Unknown Primary. Journal of Integrative Bioinformatics, 14(2). doi:10.1515/jib-2017-0013
Mortensen, L. M., Lundbye-Christensen, S., Schmidt, E. B., Calder, P. C., Schierup, M. H., Tjønneland, A., … Overvad, K. (2017). Long-chain n-3 and n-6 polyunsaturated fatty acids and risk of atrial fibrillation: Results from a Danish cohort study. PLOS ONE, 12(12), e0190262. doi:10.1371/journal.pone.0190262
Palmgren, M., Engström, K., Hallström, B. M., Wahlberg, K., Søndergaard, D. A., Säll, T., … Broberg, K. (2017). AS3MT-mediated tolerance to arsenic evolved by multiple independent horizontal gene transfers from bacteria to eukaryotes. PLOS ONE, 12(4), e0175422. doi:10.1371/journal.pone.0175422
Dyrvig, M., Qvist, P., Lichota, J., Larsen, K., Nyegaard, M., Børglum, A. D., & Christensen, J. H. (2017). DNA Methylation Analysis of BRD1 Promoter Regions and the Schizophrenia rs138880 Risk Allele. PLOS ONE, 12(1), e0170121. doi:10.1371/journal.pone.0170121
Skov, L., & Schierup, M. H. (2017). Analysis of 62 hybrid assembled human Y chromosomes exposes rapid structural changes and high rates of gene conversion. PLOS Genetics, 13(8), e1006834. doi:10.1371/journal.pgen.1006834
(2017). Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. Molecular Autism, 8(1). doi:10.1186/s13229-017-0137-9
Bolund, A. C. S., Starnawska, A., Miller, M. R., Schlünssen, V., Backer, V., Børglum, A. D., … Sigsgaard, T. (2017). Lung function discordance in monozygotic twins and associated differences in blood DNA methylation. Clinical Epigenetics, 9(1). doi:10.1186/s13148-017-0427-2
Vincent, M., Mundbjerg, K., Skou Pedersen, J., Liang, G., Jones, P. A., Ørntoft, T. F., … Wiuf, C. (2017). epiG: statistical inference and profiling of DNA methylation from whole-genome bisulfite sequencing data. Genome Biology, 18(1). doi:10.1186/s13059-017-1168-4
Schwager, E. E., Sharma, P. P., Clarke, T., Leite, D. J., Wierschin, T., Pechmann, M., … Bilde, T. (2017). The house spider genome reveals an ancient whole-genome duplication during arachnid evolution. BMC Biology, 15(1). doi:10.1186/s12915-017-0399-x
Walter, A., Bechsgaard, J., Scavenius, C., Dyrlund, T. S., Sanggaard, K. W., Enghild, J. J., & Bilde, T. (2017). Characterisation of protein families in spider digestive fluids and their role in extra-oral digestion. BMC Genomics, 18(1). doi:10.1186/s12864-017-3987-9
Pedersen, S. H., Ferchaud, A.-L., Bertelsen, M. S., Bekkevold, D., & Hansen, M. M. (2017). Low genetic and phenotypic divergence in a contact zone between freshwater and marine sticklebacks: gene flow constrains adaptation. BMC Evolutionary Biology, 17(1). doi:10.1186/s12862-017-0982-3
Madsen, T., Hobolth, A., Jensen, J. L., & Pedersen, J. S. (2017). Significance evaluation in factor graphs. BMC Bioinformatics, 18(1). doi:10.1186/s12859-017-1614-z
Rajkumar, A. P., Horsdal, H. T., Wimberley, T., Cohen, D., Mors, O., Børglum, A. D., & Gasse, C. (2017). Endogenous and Antipsychotic-Related Risks for Diabetes Mellitus in Young People With Schizophrenia: A Danish Population-Based Cohort Study. American Journal of Psychiatry, 174(7), 686–694. doi:10.1176/appi.ajp.2016.16040442
Gravholt, C. H., Dollerup, O. L., Duval, L., Mejlgaard, E., Stribolt, K., Vang, S., … Stochholm, K. (2017). A Rare Case of Embryonal Carcinoma in a Patient with Turner Syndrome without Y Chromosomal Material but Mutations in KIT, AKT1, and ZNF358 Demonstrated Using Exome Sequencing. Sexual Development, 11(5-6), 262–268. doi:10.1159/000484398
Schøler, L. V., Reinert, T., Ørntoft, M.-B. W., Kassentoft, C. G., Árnadóttir, S. S., Vang, S., … Andersen, C. L. (2017). Clinical Implications of Monitoring Circulating Tumor DNA in Patients with Colorectal Cancer. Clinical Cancer Research, 23(18), 5437–5445. doi:10.1158/1078-0432.ccr-17-0510
Hansen, M. M., & Rogers, S. M. (2017). Recipient of the 2016Molecular EcologyPrize: Louis Bernatchez - advancing the conservation of aquatic resources with his contributions on the ecological genomics of adaptation and speciation. Molecular Ecology, 26(2), 413–419. doi:10.1111/mec.13941
Eriksen, P. L., Kreutzfeldt, M., Grønbaek, H., Thorsen, K., Vang, S., Jessen, N., & Vilstrup, H. (2017). Enrichment of Genetic Variants in the Glucocorticoid Receptor Signalling Pathway in Autoimmune Hepatitis with Failure of Standard Treatment. Basic & Clinical Pharmacology & Toxicology, 121(3), 189–194. doi:10.1111/bcpt.12788
Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., & Schierup, M. H. (2017). Assembly and analysis of 100 full MHC haplotypes from the Danish population. Genome Research, 27(9), 1597–1607. doi:10.1101/gr.218891.116
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., … Werge, T. (2017). A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator. doi:10.1101/240911
Demontis, D., Rajagopal, V. M., Als, T. D., Grove, J., Pallesen, J., Hjorthøj, C., … Børglum, A. D. (2017). Genome-wide association study implicates CHRNA2 in cannabis use disorder. doi:10.1101/237321
Rheinbay, E., Nielsen, M. M., Abascal, F., Tiao, G., Hornshøj, H., Hess, J. M., … Madsen, T. (2017). Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes. doi:10.1101/237313
Lucotte, E. A., Skov, L., Coll Macià, M., Munch, K., & Schierup, M. H. (2017). Dynamic copy number evolution of X- and Y-linked ampliconic genes in human populations. doi:10.1101/228841
Warrier, V., Toro, R., Won, H., Leblond, C. S., Cliquet, F., … Delorme, R. (2017). Social and non-social autism symptom and trait domains are genetically dissociable. doi:10.1101/228254
Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., … Andrews, S. V. (2017). Elevated polygenic burden for autism is associated with differential DNA methylation at birth. doi:10.1101/225193
Grove, J., Ripke, S., Als, T. D., Mattheisen, M., Walters, R., Won, H., … Anney, R. (2017). Common risk variants identified in autism spectrum disorder. doi:10.1101/224774
Huckins, L. M., Dobbyn, A., McFadden, W., Wang, W., Ruderfer, D. M., … Hoffman, G. (2017). Transcriptomic Imputation of Bipolar Disorder and Bipolar subtypes reveals 29 novel associated genes. doi:10.1101/222786
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., … Pardinas, A. (2017). Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development. doi:10.1101/222596
Jager, M., Blokzijl, F., Kuijk, E., Bertl, J., Vougioukalaki, M., Janssen, R., … Cuppen, E. (2017). Deficiency of nucleotide excision repair explains mutational signature observed in cancer. doi:10.1101/221168
Grüning, B., Dale, R., Sjödin, A., Chapman, B. A., Rowe, J., Tomkins-Tinch, C. H., … Haudgaard, M. (2017). Bioconda: A sustainable and comprehensive software distribution for the life sciences. doi:10.1101/207092
Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., … Eley, T. C. (2017). A Major Role for Common Genetic Variation in Anxiety Disorders. doi:10.1101/203844
Klein, M., Walters, R. K., Demontis, D., Stein, J. L., Hibar, D. P., Adams, H. H., … Franke, B. (2017). Genetic markers of ADHD-related variations in intracranial volume. doi:10.1101/184192
Hornshøj, H., Nielsen, M. M., Sinnott-Armstrong, N. A., Świtnicki, M. P., Juul, M., Madsen, T., … Pedersen, J. S. (2017). Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival. doi:10.1101/182642
Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., … Loohuis, L. M. O. (2017). Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes. doi:10.1101/173435
Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., … Gaspar, H. A. (2017). Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder. doi:10.1101/173062
Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., … Andlauer, T. F. M. (2017). Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder. doi:10.1101/167577
Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., … Neale, B. M. (2017). A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder. doi:10.1101/154088
Carlevaro-Fita, J., Lanzós, A., Feuerbach, L., Hong, C., Mas-Ponte, D., … Pedersen, J. S. (2017). Unique genomic features and deeply-conserved functions of long non-coding RNAs in the Cancer LncRNA Census (CLC). doi:10.1101/152769
Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., … Christiansen, M. (2017). Mitochondrial DNA SNPs associated with Schizophrenia exhibit Highly Variable Inter-allelic Haplogroup Affiliation and Nuclear Genogeographic Affinity: Bi-Genomic Linkage Disequilibrium raises Major Concerns for Link to Disease. doi:10.1101/149070
Bybjerg-Grauholm, J., Hagen, C., Goncalves, V. F., Baekvad-Hansen, M., Hansen, C. S., Hedley, P. L., … Christiansen, M. (2017). Complex spatio-temporal distribution and genogeographic affinity of mitochondrial DNA haplogroups in 24,216 Danes. doi:10.1101/148494
Ganna, A., Satterstrom, K. F., Zekavat, S. M., Das, I., Kurki, M. I., … Churchhouse, C. (2017). Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum. doi:10.1101/148247
Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., … Cerrato, F. (2017). Discovery of the first genome-wide significant risk loci for ADHD. doi:10.1101/145581
Bertl, J., Guo, Q., Juul, M., Besenbacher, S., Muhlig Nielsen, M., Hornshøj, H., … Hobolth, A. (2017). A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data. doi:10.1101/122879
Sullivan, P. F., Agrawal, A., Bulik, C. M., Andreassen, O. A., Børglum, A. D., … Breen, G. (2017). Psychiatric Genomics: An Update and an Agenda. doi:10.1101/115600
Schwager, E. E., Sharma, P. P., Clarke, T., Leite, D. J., Wierschin, T., Pechmann, M., … Bilde, T. (2017). The house spider genome reveals an ancient whole-genome duplication during arachnid evolution. doi:10.1101/106385
Yang, T., Nagy, I., Mancinotti, D., Otterbach, S. L., Andersen, T. B., Motawia, M. S., … Geu-Flores, F. (2017). Transcript profiling of a bitter variety of narrow-leafed lupin to discover alkaloid biosynthetic genes. Journal of Experimental Botany, 68(20), 5527–5537. doi:10.1093/jxb/erx362
Gao, S., Hu, X., Xu, F., Gao, C., Xiong, K., Zhao, X., … Pedersen, C. N. S. (2017). BS-virus-finder: virus integration calling using bisulfite sequencing data. GigaScience, 7(1). doi:10.1093/gigascience/gix123
Duan, J., Sanggaard, K. W., Schauser, L., Lauridsen, S. E., Enghild, J. J., Schierup, M. H., & Wang, T. (2017). Transcriptome analysis of the response of Burmese python to digestion. GigaScience, 6(8). doi:10.1093/gigascience/gix057
Cheng, J. Y., Mailund, T., & Nielsen, R. (2017). Fast admixture analysis and population tree estimation for SNP and NGS data. Bioinformatics, 33(14), 2148–2155. doi:10.1093/bioinformatics/btx098
Leppälä, K., Nielsen, S. V., & Mailund, T. (2017). admixturegraph: an R package for admixture graph manipulation and fitting. Bioinformatics, 33(11), 1738–1740. doi:10.1093/bioinformatics/btx048
Nam, K., Munch, K., Mailund, T., Nater, A., Greminger, M. P., Krützen, M., … Schierup, M. H. (2017). Evidence that the rate of strong selective sweeps increases with population size in the great apes. Proceedings of the National Academy of Sciences, 114(7), 1613–1618. doi:10.1073/pnas.1605660114
Byrne, S. L., Erthmann, P. Ø., Agerbirk, N., Bak, S., Hauser, T. P., Nagy, I., … Asp, T. (2017). The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry. Scientific Reports, 7(1). doi:10.1038/srep40728
Jónsson, H., Sulem, P., Kehr, B., Kristmundsdottir, S., Zink, F., Hjartarson, E., … Stefansson, K. (2017). Whole genome characterization of sequence diversity of 15,220 Icelanders. Scientific Data, 4(1). doi:10.1038/sdata.2017.115
Villesen, P., & Stride Nielsen, L. (2017). Profiling of cocaine using ratios of GC-MS peaks. Scientific Reports, 7(1). doi:10.1038/s41598-017-12042-x
Rietschel, L., Streit, F., Zhu, G., McAloney, K., … Frank, J. (2017). Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes. Scientific Reports, 7(1). doi:10.1038/s41598-017-11852-3
Thomsen, M. B. H., Nordentoft, I., Lamy, P., Vang, S., Reinert, L., Mapendano, C. K., … Dyrskjøt, L. (2017). Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer. Scientific Reports, 7(1). doi:10.1038/s41598-017-11291-0
Okholm, T. L. H., Nielsen, M. M., Hamilton, M. P., Christensen, L.-L., Vang, S., Hedegaard, J., … Pedersen, J. S. (2017). Circular RNA expression is abundant and correlated to aggressiveness in early-stage bladder cancer. Npj Genomic Medicine, 2(1). doi:10.1038/s41525-017-0038-z
Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., … Timmers, P. R. H. J. (2017). Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications, 8(1). doi:10.1038/s41467-017-00934-5
Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., … Kosmicki, J. A. (2017). Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nature Genetics, 49(7), 978–985. doi:10.1038/ng.3863
McLaughlin, R. L., Schijven, D., van Rheenen, W., van Eijk, K. R., … O’Brien, M. (2017). Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nature Communications, 8(1). doi:10.1038/ncomms14774
Maretty, L., Jensen, J. M., Petersen, B., Sibbesen, J. A., Liu, S., Villesen, P., … Izarzugaza, J. M. G. (2017). Sequencing and de novo assembly of 150 genomes from Denmark as a population reference. Nature, 548(7665), 87–91. doi:10.1038/nature23264
Manuguerra, I., Grossi, G., Thomsen, R. P., Lyngsø, J., Pedersen, J. S., Kjems, J., … Gothelf, K. V. (2017). Construction of a Polyhedral DNA 12-Arm Junction for Self-Assembly of Wireframe DNA Lattices. ACS Nano, 11(9), 9041–9047. doi:10.1021/acsnano.7b03538
Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., … Agerbo, E. (2017). The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark. Psychological Medicine, 48(2), 305–314. doi:10.1017/s0033291717001696
Laursen, T. M., Trabjerg, B. B., Mors, O., Børglum, A. D., Hougaard, D. M., Mattheisen, M., … Agerbo, E. (2017). Association of the polygenic risk score for schizophrenia with mortality and suicidal behavior - A Danish population-based study. Schizophrenia Research, 184, 122–127. doi:10.1016/j.schres.2016.12.001
Qvist, P., Rajkumar, A. P., Redrobe, J. P., Nyegaard, M., Christensen, J. H., Mors, O., … Børglum, A. D. (2017). Mice heterozygous for an inactivated allele of the schizophrenia associated Brd1 gene display selective cognitive deficits with translational relevance to schizophrenia. Neurobiology of Learning and Memory, 141, 44–52. doi:10.1016/j.nlm.2017.03.009
Leng, P., Ji, Q., Asp, T., Frei, U. K., Ingvardsen, C. R., Xing, Y., … Lübberstedt, T. (2017). Auxin Binding Protein 1 Reinforces Resistance to Sugarcane Mosaic Virus in Maize. Molecular Plant, 10(10), 1357–1360. doi:10.1016/j.molp.2017.07.013
Stride Nielsen, L., Villesen, P., & Lindholst, C. (2017). Variation in chemical profiles within large seizures of cocaine bricks. Forensic Science International, 280, 194–199. doi:10.1016/j.forsciint.2017.10.007
Bramsen, J. B., Rasmussen, M. H., Ongen, H., Mattesen, T. B., Ørntoft, M.-B. W., Árnadóttir, S. S., … Andersen, C. L. (2017). Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer. Cell Reports, 19(6), 1268–1280. doi:10.1016/j.celrep.2017.04.045
Direk, N., Williams, S., Smith, J. A., Ripke, S., Air, T., Amare, A. T., … Blackwood, D. H. R. (2017). An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biological Psychiatry, 82(5), 322–329. doi:10.1016/j.biopsych.2016.11.013
Qvist, P., Christensen, J. H., Vardya, I., Rajkumar, A. P., Mørk, A., Paternoster, V., … Børglum, A. D. (2017). The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice. Biological Psychiatry, 82(1), 62–76. doi:10.1016/j.biopsych.2016.08.037
Power, R. A., Tansey, K. E., Buttenschøn, H. N., Cohen-Woods, S., Bigdeli, T., Hall, L. S., … Steinberg, S. (2017). Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biological Psychiatry, 81(4), 325–335. doi:10.1016/j.biopsych.2016.05.010
Sverrisdóttir, E., Byrne, S., Sundmark, E. H. R., Johnsen, H. Ø., Kirk, H. G., Asp, T., … Nielsen, K. L. (2017). Genomic prediction of starch content and chipping quality in tetraploid potato using genotyping-by-sequencing. Theoretical and Applied Genetics, 130(10), 2091–2108. doi:10.1007/s00122-017-2944-y
Árnadóttir, S. S., Jeppesen, M., Lamy, P., Bramsen, J. B., Nordentoft, I., Knudsen, M., … L. Andersen, C. (2017). Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures. Molecular Oncology, 12(1), 132–147. doi:10.1002/1878-0261.12156
Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., … Dehghan, A. (2017). Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations. JAMA Psychiatry, 74(12), 1214. doi:10.1001/jamapsychiatry.2017.3016

2016

(68 publications)

Fè, D., Ashraf, B. H., Pedersen, M. G., Janss, L., Byrne, S., Roulund, N., … Jensen, J. (2016). Accuracy of Genomic Prediction in a Commercial Perennial Ryegrass Breeding Program. The Plant Genome, 9(3), plantgenome2015.11.0110. doi:10.3835/plantgenome2015.11.0110
Nissen, J. B., Hansen, C. S., Starnawska, A., Mattheisen, M., Børglum, A. D., Buttenschøn, H. N., & Hollegaard, M. (2016). DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD. Frontiers in Psychiatry, 7. doi:10.3389/fpsyt.2016.00035
Vanthournout, B., Greve, M., Bruun, A., Bechsgaard, J., Overgaard, J., & Bilde, T. (2016). Benefits of Group Living Include Increased Feeding Efficiency and Lower Mass Loss during Desiccation in the Social and Inbreeding Spider Stegodyphus dumicola. Frontiers in Physiology, 7. doi:10.3389/fphys.2016.00018
Rohde, P. D., Demontis, D., Cuyabano, B. C. D., Børglum, A. D., & Sørensen, P. (2016). Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes. Genetics, 203(4), 1901–1913. doi:10.1534/genetics.116.189498
Athanasiadis, G., Cheng, J. Y., Vilhjalmsson, B. J., Jorgensen, F. G., Als, T. D., Le Hellard, S., … Mailund, T. (2016). Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity. Genetics, 204(2), 711–722. doi:10.1534/genetics.116.189241
Langkilde, A., Olsen, L. C., Sætrom, P., Drabløs, F., Besenbacher, S., Raaby, L., … Iversen, L. (2016). Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α. PLOS ONE, 11(12), e0167437. doi:10.1371/journal.pone.0167437
Athanasiadis, G., Jørgensen, F. G., Cheng, J. Y., Kjærgaard, P. C., Schierup, M. H., & Mailund, T. (2016). Spitting for Science: Danish High School Students Commit to a Large-Scale Self-Reported Genetic Study. PLOS ONE, 11(8), e0161822. doi:10.1371/journal.pone.0161822
Rabier, C.-E., Barre, P., Asp, T., Charmet, G., & Mangin, B. (2016). On the Accuracy of Genomic Selection. PLOS ONE, 11(6), e0156086. doi:10.1371/journal.pone.0156086
Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., … Hollegaard, M. V. (2016). High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA. PLOS ONE, 11(4), e0153253. doi:10.1371/journal.pone.0153253
Paina, C., Byrne, S. L., Studer, B., Rognli, O. A., & Asp, T. (2016). Using a Candidate Gene-Based Genetic Linkage Map to Identify QTL for Winter Survival in Perennial Ryegrass. PLOS ONE, 11(3), e0152004. doi:10.1371/journal.pone.0152004
Mahmood, K., Højland, D. H., Asp, T., & Kristensen, M. (2016). Transcriptome Analysis of an Insecticide Resistant Housefly Strain: Insights about SNPs and Regulatory Elements in Cytochrome P450 Genes. PLOS ONE, 11(3), e0151434. doi:10.1371/journal.pone.0151434
Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., … Borglum, A. (2016). No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study. PLOS Genetics, 12(10), e1006343. doi:10.1371/journal.pgen.1006343
Besenbacher, S., Sulem, P., Helgason, A., Helgason, H., Kristjansson, H., Jonasdottir, A., … Stefansson, K. (2016). Multi-nucleotide de novo Mutations in Humans. PLOS Genetics, 12(11), e1006315. doi:10.1371/journal.pgen.1006315
Viuff, A.-C. F., Pedersen, L. H., Kyng, K., Staunstrup, N. H., Børglum, A., & Henriksen, T. B. (2016). Antidepressant medication during pregnancy and epigenetic changes in umbilical cord blood: a systematic review. Clinical Epigenetics, 8(1). doi:10.1186/s13148-016-0262-x
Staunstrup, N. H., Starnawska, A., Nyegaard, M., Christiansen, L., Nielsen, A. L., Børglum, A., & Mors, O. (2016). Genome-wide DNA methylation profiling with MeDIP-seq using archived dried blood spots. Clinical Epigenetics, 8(1). doi:10.1186/s13148-016-0242-1
Starnawska, A., Demontis, D., McQuillin, A., O’Brien, N. L., Staunstrup, N. H., Mors, O., … Nyegaard, M. (2016). Hypomethylation of FAM63B in bipolar disorder patients. Clinical Epigenetics, 8(1). doi:10.1186/s13148-016-0221-6
Fryland, T., Christensen, J. H., Pallesen, J., Mattheisen, M., Palmfeldt, J., Bak, M., … Børglum, A. D. (2016). Identification of the BRD1 interaction network and its impact on mental disorder risk. Genome Medicine, 8(1). doi:10.1186/s13073-016-0308-x
Abascal, F., Corvelo, A., Cruz, F., Villanueva-Cañas, J. L., Vlasova, A., Marcet-Houben, M., … Godoy, J. A. (2016). Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx. Genome Biology, 17(1). doi:10.1186/s13059-016-1090-1
Lamy, P., Nordentoft, I., Birkenkamp-Demtröder, K., Thomsen, M. B. H., Villesen, P., Vang, S., … Dyrskjøt, L. (2016). Paired Exome Analysis Reveals Clonal Evolution and Potential Therapeutic Targets in Urothelial Carcinoma. Cancer Research, 76(19), 5894–5906. doi:10.1158/0008-5472.can-16-0436
Arribas-Layton, M., Dennis, J., Bennett, E. J., Damgaard, C. K., & Lykke-Andersen, J. (2016). The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation. Molecular and Cellular Biology, 36(17), 2226–2235. doi:10.1128/mcb.01102-15
Liu, S., Hansen, M. M., & Jacobsen, M. W. (2016). Region-wide and ecotype-specific differences in demographic histories of threespine stickleback populations, estimated from whole genome sequences. Molecular Ecology, 25(20), 5187–5202. doi:10.1111/mec.13827
Benito, B. M., Svenning, J.-C., Kellberg-Nielsen, T., Riede, F., Gil-Romera, G., Mailund, T., … Sandel, B. S. (2016). The ecological niche and distribution of Neanderthals during the Last Interglacial. Journal of Biogeography, 44(1), 51–61. doi:10.1111/jbi.12845
Liu, S., & Hansen, M. M. (2016). PSMC (pairwise sequentially Markovian coalescent) analysis of RAD (restriction site associated DNA) sequencing data. Molecular Ecology Resources, 17(4), 631–641. doi:10.1111/1755-0998.12606
Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., Kosmicki, J. A., … Grove, J. (2016). Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. doi:10.1101/089342
Cheng, J. Y., Mailund, T., & Nielsen, R. (2016). Ohana, a tool set for population genetic analyses of admixture components. doi:10.1101/071233
Dan, S., Christian N. S., P., & Chris, G. (2016). HydDB: A web tool for hydrogenase classification and analysis. doi:10.1101/061994
Warrier, V., Toro, R., Chakrabarti, B., Børglum, A. D., Grove, J., … Hinds, D. A. (2016). Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa. doi:10.1101/050682
Lan, T., Cheng, J., Ratan, A., Miller, W., Schuster, S. C., Farley, S., … Lindqvist, C. (2016). Genome-wide evidence for a hybrid origin of modern polar bears. doi:10.1101/047498
Marshall, C., Howrigan, D., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D., … Pinto, D. (2016). A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects. doi:10.1101/040493
Nielsen, M. M., Tataru, P., Madsen, T., Hobolth, A., & Pedersen, J. S. (2016). Regmex, Motif analysis in ranked lists of sequences. doi:10.1101/035956
Gregersen, N. O., Buttenschøn, H. N., Hedemand, A., Nielsen, M. N., Dahl, H. A., Kristensen, A. S., … Mors, O. (2016). Association between genes on chromosome 19p13.2 and panic disorder. Psychiatric Genetics, 26(6), 287–292. doi:10.1097/ypg.0000000000000147
Bendtsen, K. L., Xu, K., Luckmann, M., Winther, K. S., Shah, S. A., Pedersen, C. N. S., & Brodersen, D. E. (2016). Toxin inhibition inC. crescentusVapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Research, gkw1266. doi:10.1093/nar/gkw1266
Munch, K., Nam, K., Schierup, M. H., & Mailund, T. (2016). Selective Sweeps across Twenty Millions Years of Primate Evolution. Molecular Biology and Evolution, 33(12), 3065–3074. doi:10.1093/molbev/msw199
Hanghøj, K., Seguin-Orlando, A., Schubert, M., Madsen, T., Pedersen, J. S., Willerslev, E., & Orlando, L. (2016). Fast, Accurate and Automatic Ancient Nucleosome and Methylation Maps with epiPALEOMIX. Molecular Biology and Evolution, 33(12), 3284–3298. doi:10.1093/molbev/msw184
Sykes, T., Yates, S., Nagy, I., Asp, T., Small, I., & Studer, B. (2016). In-silicoidentification of candidate genes for fertility restoration in cytoplasmic male sterile perennial ryegrass (Lolium perenneL.). Genome Biology and Evolution, evw047. doi:10.1093/gbe/evw047
Shah, N., Hirakawa, H., Kusakabe, S., Sandal, N., Stougaard, J., Schierup, M. H., … Andersen, S. U. (2016). High-resolution genetic maps ofLotus japonicusandL. burttiibased on re-sequencing of recombinant inbred lines. DNA Research, 23(5), 487–494. doi:10.1093/dnares/dsw033
Sahoo, S., Świtnicki, M. P., & Pedersen, J. S. (2016). ProbFold: a probabilistic method for integration of probing data in RNA secondary structure prediction. Bioinformatics, 32(17), 2626–2635. doi:10.1093/bioinformatics/btw175
Trolle, C., Nielsen, M. M., Skakkebæk, A., Lamy, P., Vang, S., Hedegaard, J., … Gravholt, C. H. (2016). Widespread DNA hypomethylation and differential gene expression in Turner syndrome. Scientific Reports, 6(1). doi:10.1038/srep34220
Søndergaard, D., Pedersen, C. N. S., & Greening, C. (2016). HydDB: A web tool for hydrogenase classification and analysis. Scientific Reports, 6(1). doi:10.1038/srep34212
Kovi, M. R., Abdelhalim, M., Kunapareddy, A., Ergon, Å., Tronsmo, A. M., Brurberg, M. B., … Rognli, O. A. (2016). Global transcriptome changes in perennial ryegrass during early infection by pink snow mould. Scientific Reports, 6(1). doi:10.1038/srep28702
Franke, B., Stein, J. L., Ripke, S., Anttila, V., … Hibar, D. P. (2016). Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nature Neuroscience, 19(3), 420–431. doi:10.1038/nn.4228
Bolton, K. L., Tyrer, J., Song, H., Ramus, S. J., Notaridou, M., … Wozniak, E. (2016). Erratum: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nature Genetics, 48(1), 101–101. doi:10.1038/ng0116-101b
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., … Daly, M. J. (2016). Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. Nature Genetics, 48(5), 552–555. doi:10.1038/ng.3529
Damas, N. D., Marcatti, M., Côme, C., Christensen, L. L., Nielsen, M. M., Baumgartner, R., … Lund, A. H. (2016). SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization. Nature Communications, 7(1). doi:10.1038/ncomms13875
Rasmussen, M. H., Lyskjær, I., Jersie-Christensen, R. R., Tarpgaard, L. S., Primdal-Bengtson, B., Nielsen, M. M., … Andersen, C. L. (2016). miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells. Nature Communications, 7(1). doi:10.1038/ncomms12436
Hansen, T. B., Venø, M. T., Jensen, T. I., Schaefer, A., Damgaard, C. K., & Kjems, J. (2016). Argonaute-associated short introns are a novel class of gene regulators. Nature Communications, 7(1). doi:10.1038/ncomms11538
Malaspinas, A.-S., Westaway, M. C., Muller, C., Sousa, V. C., Lao, O., Alves, I., … Crawford, J. E. (2016). A genomic history of Aboriginal Australia. Nature, 538(7624), 207–214. doi:10.1038/nature18299
Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., … McCarroll, S. A. (2016). Schizophrenia risk from complex variation of complement component 4. Nature, 530(7589), 177–183. doi:10.1038/nature16549
Jacobsen, M. W., da Fonseca, R. R., Bernatchez, L., & Hansen, M. M. (2016). Comparative analysis of complete mitochondrial genomes suggests that relaxed purifying selection is driving high nonsynonymous evolutionary rate of the NADH2 gene in whitefish (Coregonus ssp.). Molecular Phylogenetics and Evolution, 95, 161–170. doi:10.1016/j.ympev.2015.11.008
Thomsen, M. B. H., Nordentoft, I., Lamy, P., Høyer, S., Vang, S., Hedegaard, J., … Dyrskjøt, L. (2016). Spatial and temporal clonal evolution during development of metastatic urothelial carcinoma. Molecular Oncology, 10(9), 1450–1460. doi:10.1016/j.molonc.2016.08.003
Christensen, L. L., True, K., Hamilton, M. P., Nielsen, M. M., Damas, N. D., Damgaard, C. K., … Andersen, C. L. (2016). SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism. Molecular Oncology, 10(8), 1266–1282. doi:10.1016/j.molonc.2016.06.003
Haldrup, C., Lynnerup, A.-S., Storebjerg, T. M., Vang, S., Wild, P., Visakorpi, T., … Sørensen, K. D. (2016). Large-scale evaluation of SLC18A2 in prostate cancer reveals diagnostic and prognostic biomarker potential at three molecular levels. Molecular Oncology, 10(6), 825–837. doi:10.1016/j.molonc.2016.02.001
Demontis, D., Lescai, F., Børglum, A., Glerup, S., Østergaard, S. D., Mors, O., … Franke, B. (2016). Whole-Exome Sequencing Reveals Increased Burden of Rare Functional and Disruptive Variants in Candidate Risk Genes in Individuals With Persistent Attention-Deficit/Hyperactivity Disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 55(6), 521–523. doi:10.1016/j.jaac.2016.03.009
Stride Nielsen, L., Lindholst, C., & Villesen, P. (2016). Cocaine classification using alkaloid and residual solvent profiling. Forensic Science International, 269, 42–49. doi:10.1016/j.forsciint.2016.11.007
Nielsen, L. S., Villesen, P., & Lindholst, C. (2016). Stability of cocaine impurity profiles during 12 months of storage. Forensic Science International, 264, 56–62. doi:10.1016/j.forsciint.2016.03.012
Birkenkamp-Demtröder, K., Nordentoft, I., Christensen, E., Høyer, S., Reinert, T., Vang, S., … Dyrskjøt, L. (2016). Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer. European Urology, 70(1), 75–82. doi:10.1016/j.eururo.2016.01.007
Hauberg, M. E., Holm-Nielsen, M. H., Mattheisen, M., Askou, A. L., Grove, J., Børglum, A. D., & Corydon, T. J. (2016). Schizophrenia risk variants affecting microRNA function and site-specific regulation of NT5C2 by miR-206. European Neuropsychopharmacology, 26(9), 1522–1526. doi:10.1016/j.euroneuro.2016.06.014
Hedegaard, J., Lamy, P., Nordentoft, I., Algaba, F., Høyer, S., Ulhøi, B. P., … Dyrskjøt, L. (2016). Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma. Cancer Cell, 30(1), 27–42. doi:10.1016/j.ccell.2016.05.004
Benros, M. E., Trabjerg, B. B., Meier, S., Mattheisen, M., Mortensen, P. B., Mors, O., … Agerbo, E. (2016). Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia. Biological Psychiatry, 80(8), 609–616. doi:10.1016/j.biopsych.2016.04.008
Sanggaard, K. W., Dyrlund, T. F., Bechsgaard, J. S., Scavenius, C., Wang, T., Bilde, T., & Enghild, J. J. (2016). The spider hemolymph clot proteome reveals high concentrations of hemocyanin and von Willebrand factor-like proteins. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1864(2), 233–241. doi:10.1016/j.bbapap.2015.11.004
Bak, S. T., Staunstrup, N. H., Starnawska, A., Daugaard, T. F., Nyengaard, J. R., Nyegaard, M., … Nielsen, A. L. (2016). Evaluating the Feasibility of DNA Methylation Analyses Using Long-Term Archived Brain Formalin-Fixed Paraffin-Embedded Samples. Molecular Neurobiology, 55(1), 668–681. doi:10.1007/s12035-016-0345-x
Amidi, A., Agerbæk, M., Wu, L. M., Pedersen, A. D., Mehlsen, M., Clausen, C. R., … Zachariae, R. (2016). Changes in cognitive functions and cerebral grey matter and their associations with inflammatory markers, endocrine markers, and APOE genotypes in testicular cancer patients undergoing treatment. Brain Imaging and Behavior, 11(3), 769–783. doi:10.1007/s11682-016-9552-3
Sparvath, S. L., Geary, C. W., & Andersen, E. S. (2016). Computer-Aided Design of RNA Origami Structures. 3D DNA Nanostructure, 51–80. doi:10.1007/978-1-4939-6454-3_5
Søndergaard, D., Knudsen, M., & Pedersen, C. N. S. (2016). Computational Classification of P-Type ATPases. Methods in Molecular Biology, 493–502. doi:10.1007/978-1-4939-3179-8_41
Paternoster, V., Edhager, A. V., Sibbersen, C., Nielsen, A. L., Børglum, A. D., Christensen, J. H., & Palmfeldt, J. (2016). Quantitative assessment of methyl-esterification and other side reactions in a standard propionylation protocol for detection of histone modifications. PROTEOMICS, 16(14), 2059–2063. doi:10.1002/pmic.201500425
Settepani, V., Bechsgaard, J., & Bilde, T. (2016). Phylogenetic analysis suggests that sociality is associated with reduced effectiveness of selection. Ecology and Evolution, 6(2), 469–477. doi:10.1002/ece3.1886
Gregersen, N. O., Lescai, F., Liang, J., Li, Q., Als, T., Buttenschøn, H. N., … Demontis, D. (2016). Whole-exome sequencing implicatesDGKHas a risk gene for panic disorder in the Faroese population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171(8), 1013–1022. doi:10.1002/ajmg.b.32464
Hauberg, M. E., Roussos, P., Grove, J., Børglum, A. D., & Mattheisen, M. (2016). Analyzing the Role of MicroRNAs in Schizophrenia in the Context of Common Genetic Risk Variants. JAMA Psychiatry, 73(4), 369. doi:10.1001/jamapsychiatry.2015.3018

2015

(46 publications)

Kovi, M. R., Fjellheim, S., Sandve, S. R., Larsen, A., Rudi, H., Asp, T., … Rognli, O. A. (2015). Population Structure, Genetic Variation, and Linkage Disequilibrium in Perennial Ryegrass Populations Divergently Selected for Freezing Tolerance. Frontiers in Plant Science, 6. doi:10.3389/fpls.2015.00929
Abeynayake, S. W., Etzerodt, T. P., JonaviÄienÄ—, K., Byrne, S., Asp, T., & Boelt, B. (2015). Fructan metabolism and changes in fructan composition during cold acclimation in perennial ryegrass. Frontiers in Plant Science, 6. doi:10.3389/fpls.2015.00329
Søndergaard, D., & Pedersen, C. N. S. (2015). PATBox: A Toolbox for Classification and Analysis of P-Type ATPases. PLOS ONE, 10(9), e0139571. doi:10.1371/journal.pone.0139571
Dutheil, J. Y., Munch, K., Nam, K., Mailund, T., & Schierup, M. H. (2015). Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence. PLOS Genetics, 11(8), e1005451. doi:10.1371/journal.pgen.1005451
Nyegaard, M., Rendtorff, N. D., Nielsen, M. S., Corydon, T. J., Demontis, D., Starnawska, A., … Børglum, A. D. (2015). A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. PLOS Genetics, 11(7), e1005386. doi:10.1371/journal.pgen.1005386
Liu, S., Huang, S., Rao, J., Ye, W., Krogh, A., & Wang, J. (2015). Discovery, genotyping and characterization of structural variation and novel sequence at single nucleotide resolution from de novo genome assemblies on a population scale. GigaScience, 4(1). doi:10.1186/s13742-015-0103-4
Abeynayake, S. W., Byrne, S., Nagy, I., Jonavičienė, K., Etzerodt, T. P., Boelt, B., & Asp, T. (2015). Changes in Lolium perenne transcriptome during cold acclimation in two genotypes adapted to different climatic conditions. BMC Plant Biology, 15(1). doi:10.1186/s12870-015-0643-x
Fè, D., Cericola, F., Byrne, S., Lenk, I., Ashraf, B. H., Pedersen, M. G., … Jensen, J. (2015). Genomic dissection and prediction of heading date in perennial ryegrass. BMC Genomics, 16(1). doi:10.1186/s12864-015-2163-3
Luo, Y., Blechingberg, J., Fernandes, A. M., Li, S., Fryland, T., Børglum, A. D., … Nielsen, A. L. (2015). EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions. BMC Genomics, 16(1). doi:10.1186/s12864-015-2125-9
Rajkumar, A. P., Qvist, P., Lazarus, R., Lescai, F., Ju, J., Nyegaard, M., … Christensen, J. H. (2015). Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq. BMC Genomics, 16(1). doi:10.1186/s12864-015-1767-y
Czaban, A., Sharma, S., Byrne, S. L., Spannagl, M., Mayer, K. F., & Asp, T. (2015). Comparative transcriptome analysis within the Lolium/Festuca species complex reveals high sequence conservation. BMC Genomics, 16(1). doi:10.1186/s12864-015-1447-y
Reinert, T., Schøler, L. V., Thomsen, R., Tobiasen, H., Vang, S., Nordentoft, I., … Andersen, C. L. (2015). Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery. Gut, 65(4), 625–634. doi:10.1136/gutjnl-2014-308859
Byrne, S. L., Nagy, I., Pfeifer, M., Armstead, I., Swain, S., Studer, B., … Asp, T. (2015). A synteny-based draft genome sequence of the forage grassLolium perenne. The Plant Journal, 84(4), 816–826. doi:10.1111/tpj.13037
Ferchaud, A.-L., & Hansen, M. M. (2015). The impact of selection, gene flow and demographic history on heterogeneous genomic divergence: three-spine sticklebacks in divergent environments. Molecular Ecology, 25(1), 238–259. doi:10.1111/mec.13399
Bechsgaard, J., Vanthournout, B., Funch, P., Vestbo, S., Gibbs, R. A., Richards, S., … Bilde, T. (2015). Comparative genomic study of arachnid immune systems indicates loss of beta-1,3-glucanase-related proteins and the immune deficiency pathway. Journal of Evolutionary Biology, 29(2), 277–291. doi:10.1111/jeb.12780
Hansen, M. C., Nyvold, C. G., Roug, A. S., Kjeldsen, E., Villesen, P., Nederby, L., & Hokland, P. (2015). Nature and nurture: a case of transcending haematological pre-malignancies in a pair of monozygotic twins adding possible clues on the pathogenesis of B-cell proliferations. British Journal of Haematology, 169(3), 391–400. doi:10.1111/bjh.13305
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J., Bulik-Sullivan, B., Grove, J., … Daly, M. J. (2015). Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. doi:10.1101/027771
Jacobsen, M. W., Pujolar, J. M., & Hansen, M. M. (2015). Relationship between amino acid changes in mitochondrial ATP6 and life-history variation in anguillid eels. Biology Letters, 11(3), 20150014. doi:10.1098/rsbl.2015.0014
Luo, X.-J., Mattheisen, M., Li, M., Huang, L., Rietschel, M., … Børglum, A. D. (2015). Systematic Integration of Brain eQTL and GWAS IdentifiesZNF323as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function. Schizophrenia Bulletin, 41(6), 1294–1308. doi:10.1093/schbul/sbv017
Hansen, T. B., Venø, M. T., Damgaard, C. K., & Kjems, J. (2015). Comparison of circular RNA prediction tools. Nucleic Acids Research, 44(6), e58–e58. doi:10.1093/nar/gkv1458
Sükösd, Z., Andersen, E. S., Seemann, S. E., Jensen, M. K., Hansen, M., Gorodkin, J., & Kjems, J. (2015). Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain. Nucleic Acids Research, gkv1039. doi:10.1093/nar/gkv1039
Manzanares, C., Barth, S., Thorogood, D., Byrne, S. L., Yates, S., Czaban, A., … Studer, B. (2015). A Gene Encoding a DUF247 Domain Protein Cosegregates with theSSelf-Incompatibility Locus in Perennial Ryegrass. Molecular Biology and Evolution, 33(4), 870–884. doi:10.1093/molbev/msv335
Stevison, L. S., Woerner, A. E., Kidd, J. M., Kelley, J. L., Veeramah, K. R., … McManus, K. F. (2015). The Time Scale of Recombination Rate Evolution in Great Apes. Molecular Biology and Evolution, 33(4), 928–945. doi:10.1093/molbev/msv331
Bataillon, T., Duan, J., Hvilsom, C., Jin, X., Li, Y., Skov, L., … Schierup, M. H. (2015). Inference of Purifying and Positive Selection in Three Subspecies of Chimpanzees (Pan troglodytes) from Exome Sequencing. Genome Biology and Evolution, 7(4), 1122–1132. doi:10.1093/gbe/evv058
Knudsen, M., Søndergaard, D., Tofting-Olesen, C., Hansen, F. T., Brodersen, D. E., & Pedersen, C. N. S. (2015). Computational discovery of specificity-conferring sites in non-ribosomal peptide synthetases. Bioinformatics, 32(3), 325–329. doi:10.1093/bioinformatics/btv600
Fonseca, B. D., Zakaria, C., Jia, J.-J., Graber, T. E., Svitkin, Y., Tahmasebi, S., … Damgaard, C. K. (2015). La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1). Journal of Biological Chemistry, 290(26), 15996–16020. doi:10.1074/jbc.m114.621730
Nam, K., Munch, K., Hobolth, A., Dutheil, J. Y., Veeramah, K. R., … Woerner, A. E. (2015). Extreme selective sweeps independently targeted the X chromosomes of the great apes. Proceedings of the National Academy of Sciences, 112(20), 6413–6418. doi:10.1073/pnas.1419306112
Björkman, A., Qvist, P., Du, L., Bartish, M., Zaravinos, A., Georgiou, K., … Pan-Hammarström, Q. (2015). Aberrant recombination and repair during immunoglobulin class switching in BRCA1-deficient human B cells. Proceedings of the National Academy of Sciences, 112(7), 2157–2162. doi:10.1073/pnas.1418947112
Berger-Tal, R., Lubin, Y., Settepani, V., Majer, M., Bilde, T., & Tuni, C. (2015). Evidence for loss of nepotism in the evolution of permanent sociality. Scientific Reports, 5(1). doi:10.1038/srep13284
Loh, P.-R., Bhatia, G., Gusev, A., Finucane, H. K., Bulik-Sullivan, B. K., … Price, A. L. (2015). Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nature Genetics, 47(12), 1385–1392. doi:10.1038/ng.3431
Gudbjartsson, D. F., Helgason, H., Gudjonsson, S. A., Zink, F., Oddson, A., Gylfason, A., … Stefansson, K. (2015). Large-scale whole-genome sequencing of the Icelandic population. Nature Genetics, 47(5), 435–444. doi:10.1038/ng.3247
Bulik-Sullivan, B. K., Loh, P.-R., Finucane, H. K., Ripke, S., Yang, J., … Neale, B. M. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics, 47(3), 291–295. doi:10.1038/ng.3211
Penner, R. C., Andersen, E. S., Jensen, J. L., Kantcheva, A. K., Bublitz, M., Nissen, P., … Andersen, J. E. (2015). Erratum: Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. Nature Communications, 6(1). doi:10.1038/ncomms7209
Besenbacher, S., Liu, S., Izarzugaza, J. M. G., Grove, J., Belling, K., Bork-Jensen, J., … Rasmussen, S. (2015). Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. Nature Communications, 6(1). doi:10.1038/ncomms6969
Grinsted, L., Bilde, T., & Gilbert, J. D. J. (2015). Questioning evidence of group selection in spiders. Nature, 524(7566), E1–E3. doi:10.1038/nature14595
Crook, D. A., Lowe, W. H., Allendorf, F. W., Erős, T., Finn, D. S., Gillanders, B. M., … Hughes, J. M. (2015). Human effects on ecological connectivity in aquatic ecosystems: Integrating scientific approaches to support management and mitigation. Science of The Total Environment, 534, 52–64. doi:10.1016/j.scitotenv.2015.04.034
Debost, J.-C., Petersen, L., Grove, J., Hedemand, A., Khashan, A., Henriksen, T., … Mortensen, P. B. (2015). Investigating interactions between early life stress and two single nucleotide polymorphisms in HSD11B2 on the risk of schizophrenia. Psychoneuroendocrinology, 60, 18–27. doi:10.1016/j.psyneuen.2015.05.013
Yu, X., Pijut, P. M., Byrne, S., Asp, T., Bai, G., & Jiang, Y. (2015). Candidate gene association mapping for winter survival and spring regrowth in perennial ryegrass. Plant Science, 235, 37–45. doi:10.1016/j.plantsci.2015.03.003
Hansen, M. C., Nederby, L., Roug, A., Villesen, P., Kjeldsen, E., Nyvold, C. G., & Hokland, P. (2015). Novel scripts for improved annotation and selection of variants from whole exome sequencing in cancer research. MethodsX, 2, 145–153. doi:10.1016/j.mex.2015.03.003
Kirkegaard, K., Villesen, P., Jensen, J. M., Hindkjær, J. J., Kølvraa, S., Ingerslev, H. J., & Lykke-Hartmann, K. (2015). Distinct differences in global gene expression profiles in non-implanted blastocysts and blastocysts resulting in live birth. Gene, 571(2), 212–220. doi:10.1016/j.gene.2015.06.057
Cheng, J. Y., & Mailund, T. (2015). Ancestral population genomics using coalescence hidden Markov models and heuristic optimisation algorithms. Computational Biology and Chemistry, 57, 80–92. doi:10.1016/j.compbiolchem.2015.02.001
Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., … Do, R. (2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. The American Journal of Human Genetics, 97(4), 576–592. doi:10.1016/j.ajhg.2015.09.001
Nexø, B. A., Villesen, P., Nissen, K. K., Lindegaard, H. M., Rossing, P., Petersen, T., … Laska, M. J. (2015). Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci. Immunologic Research, 64(1), 55–63. doi:10.1007/s12026-015-8671-z
Ashraf, B. H., Byrne, S., Fé, D., Czaban, A., Asp, T., Pedersen, M. G., … Janss, L. L. (2015). Estimating genomic heritabilities at the level of family-pool samples of perennial ryegrass using genotyping-by-sequencing. Theoretical and Applied Genetics, 129(1), 45–52. doi:10.1007/s00122-015-2607-9
Bigdeli, T. B., Ripke, S., Bacanu, S.-A., Lee, S. H., Wray, N. R., … Gejman, P. V. (2015). Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171(2), 276–289. doi:10.1002/ajmg.b.32402
Agerbo, E., Sullivan, P. F., Vilhjálmsson, B. J., Pedersen, C. B., Mors, O., Børglum, A. D., … Mortensen, P. B. (2015). Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia. JAMA Psychiatry, 72(7), 635. doi:10.1001/jamapsychiatry.2015.0346

2014

(38 publications)

Forstner, A., Basmanav, F. B., Mattheisen, M., Böhmer, A., Hollegaard, M., Janson, E., … Cichon, S. (2014). Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia. Journal of Psychiatry & Neuroscience, 39(6), 386–396. doi:10.1503/jpn.130189
Paina, C., Byrne, S. L., Domnisoru, C., & Asp, T. (2014). Vernalization Mediated Changes in the Lolium perenne Transcriptome. PLoS ONE, 9(9), e107365. doi:10.1371/journal.pone.0107365
Farrell, J. D., Byrne, S., Paina, C., & Asp, T. (2014). De Novo Assembly of the Perennial Ryegrass Transcriptome Using an RNA-Seq Strategy. PLoS ONE, 9(8), e103567. doi:10.1371/journal.pone.0103567
Hedegaard, J., Thorsen, K., Lund, M. K., Hein, A.-M. K., Hamilton-Dutoit, S. J., Vang, S., … Dyrskjøt, L. (2014). Next-Generation Sequencing of RNA and DNA Isolated from Paired Fresh-Frozen and Formalin-Fixed Paraffin-Embedded Samples of Human Cancer and Normal Tissue. PLoS ONE, 9(5), e98187. doi:10.1371/journal.pone.0098187
Pedersen, B. P., Ifrim, G., Liboriussen, P., Axelsen, K. B., Palmgren, M. G., Nissen, P., … Pedersen, C. N. S. (2014). Large Scale Identification and Categorization of Protein Sequences Using Structured Logistic Regression. PLoS ONE, 9(1), e85139. doi:10.1371/journal.pone.0085139
Marcheco-Teruel, B., Parra, E. J., Fuentes-Smith, E., Salas, A., Buttenschøn, H. N., Demontis, D., … Mors, O. (2014). Cuba: Exploring the History of Admixture and the Genetic Basis of Pigmentation Using Autosomal and Uniparental Markers. PLoS Genetics, 10(7), e1004488. doi:10.1371/journal.pgen.1004488
Juraeva, D., Haenisch, B., Zapatka, M., Frank, J., Witt, S. H., … Mühleisen, T. W. (2014). Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia. PLoS Genetics, 10(6), e1004345. doi:10.1371/journal.pgen.1004345
Lindgreen, S., Krogh, A., & Pedersen, J. S. (2014). SNPest: a probabilistic graphical model for estimating genotypes. BMC Research Notes, 7(1). doi:10.1186/1756-0500-7-698
Qian, Y., Besenbacher, S., Mailund, T., & Schierup, M. H. (2014). Identifying disease associated genes by network propagation. BMC Systems Biology, 8(Suppl 1), S6. doi:10.1186/1752-0509-8-s1-s6
Schaldemose, E. L., Horjales-Araujo, E., Demontis, D., Eørglum, A. D., Svensson, P., & Finnerup, N. B. (2014). No Association of Polymorphisms in the Serotonin Transporter Gene with Thermal Pain Sensation in Healthy Individuals. Molecular Pain, 10, 1744–8069–10–76. doi:10.1186/1744-8069-10-76
Ferchaud, A.-L., Pedersen, S. H., Bekkevold, D., Jian, J., Niu, Y., & Hansen, M. M. (2014). A low-density SNP array for analyzing differential selection in freshwater and marine populations of threespine stickleback (Gasterosteus aculeatus). BMC Genomics, 15(1), 867. doi:10.1186/1471-2164-15-867
Ulrik, M. G., Pujolar, J., Ferchaud, A.-L., Jacobsen, M. W., Als, T. D., Gagnaire, P., … Hansen, M. M. (2014). Do North Atlantic eels show parallel patterns of spatially varying selection? BMC Evolutionary Biology, 14(1), 138. doi:10.1186/1471-2148-14-138
Hansen, M. M., Limborg, M. T., Ferchaud, A.-L., & Pujolar, J.-M. (2014). The effects of Medieval dams on genetic divergence and demographic history in brown trout populations. BMC Evolutionary Biology, 14(1), 122. doi:10.1186/1471-2148-14-122
Mailund, T., Munch, K., & Schierup, M. H. (2014). Lineage Sorting in Apes. Annual Review of Genetics, 48(1), 519–535. doi:10.1146/annurev-genet-120213-092532
Geary, C., Rothemund, P. W. K., & Andersen, E. S. (2014). A single-stranded architecture for cotranscriptional folding of RNA nanostructures. Science, 345(6198), 799–804. doi:10.1126/science.1253920
Jarvis, E. D., Mirarab, S., Aberer, A. J., Li, B., Houde, P., Li, C., … Howard, J. T. (2014). Whole-genome analyses resolve early branches in the tree of life of modern birds. Science, 346(6215), 1320–1331. doi:10.1126/science.1253451
Islam, M. S., Studer, B., Møller, I. M., & Asp, T. (2014). Genetics and biology of cytoplasmic male sterility and its applications in forage and turf grass breeding. Plant Breeding, 133(3), 299–312. doi:10.1111/pbr.12155
Jacobsen, M. W., Pujolar, J. M., Bernatchez, L., Munch, K., Jian, J., Niu, Y., & Hansen, M. M. (2014). Genomic footprints of speciation in Atlantic eels (Anguilla anguillaandA. rostrata). Molecular Ecology, 23(19), 4785–4798. doi:10.1111/mec.12896
Grinsted, L., Breuker, C. J., & Bilde, T. (2014). COOPERATIVE BREEDING FAVORS MATERNAL INVESTMENT IN SIZE OVER NUMBER OF EGGS IN SPIDERS. Evolution, 68(7), 1961–1973. doi:10.1111/evo.12411
Rajkumar, A. P., Christensen, J. H., Mattheisen, M., Jacobsen, I., Bache, I., Pallesen, J., … Børglum, A. D. (2014). Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder. Bipolar Disorders, 17(2), 205–211. doi:10.1111/bdi.12239
Dutheil, J. Y., Munch, K., Nam, K., Mailund, T., & Schierup, M. (2014). Strong selective sweeps on the X chromosome in the human-chimpanzee ancestor explain its low divergence. doi:10.1101/011601
Gregersen, N. O., Buttenschøn, H. N., Hedemand, A., Dahl, H. A., Kristensen, A. S., Clementsen, B., … Mors, O. (2014). Are TMEM genes potential candidate genes for panic disorder? Psychiatric Genetics, 24(1), 37–41. doi:10.1097/ypg.0000000000000022
Hansen, T. B., Venø, M. T., Kjems, J., & Damgaard, C. K. (2014). miRdentify: high stringency miRNA predictor identifies several novel animal miRNAs. Nucleic Acids Research, 42(16), e124–e124. doi:10.1093/nar/gku598
Pettersson, O. J., Aagaard, L., Andrejeva, D., Thomsen, R., Jensen, T. G., & Damgaard, C. K. (2014). DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1. Nucleic Acids Research, 42(11), 7186–7200. doi:10.1093/nar/gku352
Sand, A., Holt, M. K., Johansen, J., Brodal, G. S., Mailund, T., & Pedersen, C. N. S. (2014). tqDist: a library for computing the quartet and triplet distances between binary or general trees. Bioinformatics, 30(14), 2079–2080. doi:10.1093/bioinformatics/btu157
Penner, R. C., Andersen, E. S., Jensen, J. L., Kantcheva, A. K., Bublitz, M., Nissen, P., … Andersen, J. E. (2014). Hydrogen bond rotations as a uniform structural tool for analyzing protein architecture. Nature Communications, 5(1). doi:10.1038/ncomms6803
Sanggaard, K. W., Bechsgaard, J. S., Fang, X., Duan, J., Dyrlund, T. F., Gupta, V., … Wang, J. (2014). Spider genomes provide insight into composition and evolution of venom and silk. Nature Communications, 5(1). doi:10.1038/ncomms4765
(2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511(7510), 421–427. doi:10.1038/nature13595
Li, S., Besenbacher, S., Li, Y., Kristiansen, K., Grarup, N., Albrechtsen, A., … Schierup, M. H. (2014). Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population. European Journal of Human Genetics, 22(8), 1040–1045. doi:10.1038/ejhg.2013.282
Elfving, B., Buttenschøn, H. N., Foldager, L., Poulsen, P. H. P., Grynderup, M. B., Hansen, Å. M., … Mors, O. (2014). Depression and BMI influences the serum vascular endothelial growth factor level. The International Journal of Neuropsychopharmacology, 17(09), 1409–1417. doi:10.1017/s1461145714000273
Nordentoft, I., Lamy, P., Birkenkamp-Demtröder, K., Shumansky, K., Vang, S., Hornshøj, H., … Ørntoft, T. F. (2014). Mutational Context and Diverse Clonal Development in Early and Late Bladder Cancer. Cell Reports, 7(5), 1649–1663. doi:10.1016/j.celrep.2014.04.038
Gingold, H., Tehler, D., Christoffersen, N. R., Nielsen, M. M., Asmar, F., Kooistra, S. M., … Pilpel, Y. (2014). A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation. Cell, 158(6), 1281–1292. doi:10.1016/j.cell.2014.08.011
Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., … Stahl, E. (2014). Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. The American Journal of Human Genetics, 95(5), 535–552. doi:10.1016/j.ajhg.2014.10.004
Grove, J., Børglum, A. D., & Pearce, B. D. (2014). GWAS, Cytomegalovirus Infection, and Schizophrenia. Current Behavioral Neuroscience Reports, 1(4), 215–223. doi:10.1007/s40473-014-0022-1
Birrer, M., Kölliker, R., Manzanares, C., Asp, T., & Studer, B. (2014). A DNA marker assay based on high-resolution melting curve analysis for distinguishing species of the Festuca–Lolium complex. Molecular Breeding, 34(2), 421–429. doi:10.1007/s11032-014-0044-0
Ashraf, B. H., Jensen, J., Asp, T., & Janss, L. L. (2014). Association studies using family pools of outcrossing crops based on allele-frequency estimates from DNA sequencing. Theoretical and Applied Genetics, 127(6), 1331–1341. doi:10.1007/s00122-014-2300-4
Munch, K., Schierup, M. H., & Mailund, T. (2014). Unraveling recombination rate evolution using ancestral recombination maps. BioEssays, 36(9), 892–900. doi:10.1002/bies.201400047
Nicodemus, K. K., Hargreaves, A., Morris, D., Anney, R., Gill, M., Corvin, A., & Donohoe, G. (2014). Variability in Working Memory Performance Explained by Epistasis vs Polygenic Scores in theZNF804APathway. JAMA Psychiatry, 71(7), 778. doi:10.1001/jamapsychiatry.2014.528

2013

(24 publications)

Kristensen, T. G., Nielsen, J., & Pedersen, C. N. S. (2013). METHODS FOR SIMILARITY-BASED VIRTUAL SCREENING. Computational and Structural Biotechnology Journal, 5(6), e201302009. doi:10.5936/csbj.201302009
Tataru, P., Sand, A., Hobolth, A., Mailund, T., & Pedersen, C. (2013). Algorithms for Hidden Markov Models Restricted to Occurrences of Regular Expressions. Biology, 2(4), 1282–1295. doi:10.3390/biology2041282
Sand, A., Holt, M., Johansen, J., Fagerberg, R., Brodal, G., Pedersen, C., & Mailund, T. (2013). Algorithms for Computing the Triplet and Quartet Distances for Binary and General Trees. Biology, 2(4), 1189–1209. doi:10.3390/biology2041189
Horjales-Araujo, E., Demontis, D., Lund, E. K., Finnerup, N. B., Børglum, A. D., Jensen, T. S., … Vase, L. (2013). Polymorphism in Serotonin Receptor 3B Is Associated with Pain Catastrophizing. PLoS ONE, 8(11), e78889. doi:10.1371/journal.pone.0078889
Nexø, B. A., Hansen, B., Nissen, K. K., Gundestrup, L., Terkelsen, T., Villesen, P., … Laska, M. J. (2013). Restriction Genes for Retroviruses Influence the Risk of Multiple Sclerosis. PLoS ONE, 8(9), e74063. doi:10.1371/journal.pone.0074063
Schork, A. J., Thompson, W. K., Pham, P., Torkamani, A., Roddey, J. C., … Sullivan, P. F. (2013). All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs. PLoS Genetics, 9(4), e1003449. doi:10.1371/journal.pgen.1003449
Nielsen, M. M., Tehler, D., Vang, S., Sudzina, F., Hedegaard, J., Nordentoft, I., … Pedersen, J. S. (2013). Identification of expressed and conserved human noncoding RNAs. RNA, 20(2), 236–251. doi:10.1261/rna.038927.113
Nissen, K. K., Laska, M. J., Hansen, B., Terkelsen, T., Villesen, P., Bahrami, S., … Nexø, B. A. (2013). Endogenous retroviruses and multiple sclerosis–new pieces to the puzzle. BMC Neurology, 13(1). doi:10.1186/1471-2377-13-111
Sükösd, Z., Knudsen, B., Anderson, J. W., Novák, Á., Kjems, J., & Pedersen, C. N. (2013). Characterising RNA secondary structure space using information entropy. BMC Bioinformatics, 14(S2). doi:10.1186/1471-2105-14-s2-s22
Sand, A., Brodal, G., Fagerberg, R., Pedersen, C. N., & Mailund, T. (2013). A practical O(n log2 n) time algorithm for computing the triplet distance on binary trees. BMC Bioinformatics, 14(Suppl 2), S18. doi:10.1186/1471-2105-14-s2-s18
Sand, A., Kristiansen, M., Pedersen, C. N., & Mailund, T. (2013). zipHMMlib: a highly optimised HMM library exploiting repetitions in the input to speed up the forward algorithm. BMC Bioinformatics, 14(1). doi:10.1186/1471-2105-14-339
Berger-Tal, R., Tuni, C., Lubin, Y., Smith, D., & Bilde, T. (2013). FITNESS CONSEQUENCES OF OUTCROSSING IN A SOCIAL SPIDER WITH AN INBREEDING MATING SYSTEM. Evolution, 68(2), 343–351. doi:10.1111/evo.12264
Pedersen, J. S., Valen, E., Velazquez, A. M. V., Parker, B. J., Rasmussen, M., Lindgreen, S., … Orlando, L. (2013). Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome. Genome Research, 24(3), 454–466. doi:10.1101/gr.163592.113
Munch, K., Mailund, T., Dutheil, J. Y., & Schierup, M. H. (2013). A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion. Genome Research, 24(3), 467–474. doi:10.1101/gr.158469.113
Buttenschøn, H. N., Jacobsen, I. S., Grynderup, M. B., Hansen, Å. M., Kolstad, H. A., Kaerlev, L., … Mors, O. (2013). An association study between the norepinephrine transporter gene and depression. Psychiatric Genetics, 23(5), 217–221. doi:10.1097/ypg.0000000000000003
Bønnelykke, K., Sleiman, P., Nielsen, K., Kreiner-Møller, E., Mercader, J. M., Belgrave, D., … Bisgaard, H. (2013). A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nature Genetics, 46(1), 51–55. doi:10.1038/ng.2830
Ripke, S., O’Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., … Crowley, J. J. (2013). Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature Genetics, 45(10), 1150–1159. doi:10.1038/ng.2742
Prado-Martinez, J., Sudmant, P. H., Kidd, J. M., Li, H., Kelley, J. L., Lorente-Galdos, B., … Santpere, G. (2013). Great ape genetic diversity and population history. Nature, 499(7459), 471–475. doi:10.1038/nature12228
Horjales-Araujo, E., Demontis, D., Lund, E. K., Vase, L., Finnerup, N. B., Brglum, A. D., … Svensson, P. (2013). Emotional modulation of muscle pain is associated with polymorphisms in the serotonin transporter gene. Pain, 154(8), 1469–1476. doi:10.1016/j.pain.2013.05.011
Buttenschøn, H. N., Flint, T. J., Foldager, L., Qin, P., Christoffersen, S., Hansen, N. F., … Mors, O. (2013). An association study of suicide and candidate genes in the serotonergic system. Journal of Affective Disorders, 148(2-3), 291–298. doi:10.1016/j.jad.2012.12.011
Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B. M., … Kahn, R. S. (2013). Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume. Biological Psychiatry, 73(6), 525–531. doi:10.1016/j.biopsych.2012.08.017
Andersen, L. N., Mailund, T., & Hobolth, A. (2013). Efficient computation in the IM model. Journal of Mathematical Biology, 68(6), 1423–1451. doi:10.1007/s00285-013-0671-9
Sükösd, Z., Andersen, E. S., & Lyngsø, R. (2013). SCFGs in RNA Secondary Structure Prediction RNA secondary structure prediction : A Hands-on Approach. RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods, 143–162. doi:10.1007/978-1-62703-709-9_8
Thomsen, R., Pallesen, J., Daugaard, T. F., Børglum, A. D., & Nielsen, A. L. (2013). Genome wide assessment of mRNA in astrocyte protrusions by direct RNA sequencing reveals mRNA localization for the intermediate filament protein nestin. Glia, 61(11), 1922–1937. doi:10.1002/glia.22569

2012

(27 publications)

Pedersen, C. N. S., Axelsen, K. B., Harper, J. F., & Palmgren, M. G. (2012). Evolution of Plant P-Type ATPases. Frontiers in Plant Science, 3. doi:10.3389/fpls.2012.00031
Jin, X., He, M., Ferguson, B., Meng, Y., Ouyang, L., Ren, J., … Wang, X. (2012). An Effort to Use Human-Based Exome Capture Methods to Analyze Chimpanzee and Macaque Exomes. PLoS ONE, 7(7), e40637. doi:10.1371/journal.pone.0040637
Walker, R. S., Wichmann, S., Mailund, T., & Atkisson, C. J. (2012). Cultural Phylogenetics of the Tupi Language Family in Lowland South America. PLoS ONE, 7(4), e35025. doi:10.1371/journal.pone.0035025
Pedersen, J. M., Fredsoe, J., Roedgaard, M., Andreasen, L., Mundbjerg, K., Kruhøffer, M., … Andersen, A. H. (2012). DNA Topoisomerases Maintain Promoters in a State Competent for Transcriptional Activation in Saccharomyces cerevisiae. PLoS Genetics, 8(12), e1003128. doi:10.1371/journal.pgen.1003128
Mailund, T., Halager, A. E., Westergaard, M., Dutheil, J. Y., Munch, K., Andersen, L. N., … Schierup, M. H. (2012). A New Isolation with Migration Model along Complete Genomes Infers Very Different Divergence Processes among Closely Related Great Ape Species. PLoS Genetics, 8(12), e1003125. doi:10.1371/journal.pgen.1003125
Nyegaard, M., Demontis, D., Thestrup, B. B., Hedemand, A., Sørensen, K. M., Hansen, T., … Børglum, A. D. (2012). No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia. Psychiatric Genetics, 22(3), 146–148. doi:10.1097/ypg.0b013e328353953c
Demontis, D., Nyegaard, M., Christensen, J. H., Severinsen, J., Hedemand, A., Hansen, T., … Børglum, A. D. (2012). The gene encoding the melanin-concentrating hormone receptor 1 is associated with schizophrenia in a Danish case–control sample. Psychiatric Genetics, 22(2), 62–69. doi:10.1097/ypg.0b013e32834dc424
Petersen, M., Andersen, J. T., Jimenez-Solem, E., Broedbaek, K., Afzal, S., Nyegaard, M., … Poulsen, H. E. (2012). Effect of specific ADRB1/ADRB2/AGT genotype combinations on the association between survival and carvedilol treatment in chronic heart failure. Pharmacogenetics and Genomics, 22(10), 709–715. doi:10.1097/fpc.0b013e3283540286
Gupta, V., Markmann, K., Pedersen, C. N. S., Stougaard, J., & Andersen, S. U. (2012). shortran: a pipeline for small RNA-seq data analysis. Bioinformatics, 28(20), 2698–2700. doi:10.1093/bioinformatics/bts496
Sukosd, Z., Knudsen, B., Kjems, J., & Pedersen, C. N. S. (2012). PPfold 3.0: fast RNA secondary structure prediction using phylogeny and auxiliary data. Bioinformatics, 28(20), 2691–2692. doi:10.1093/bioinformatics/bts488
Hilker, R., Sickinger, C., Pedersen, C. N. S., & Stoye, J. (2012). UniMoG--a unifying framework for genomic distance calculation and sorting based on DCJ. Bioinformatics, 28(19), 2509–2511. doi:10.1093/bioinformatics/bts440
Miller, W., Schuster, S. C., Welch, A. J., Ratan, A., Bedoya-Reina, O. C., Zhao, F., … Lindqvist, C. (2012). Polar and brown bear genomes reveal ancient admixture and demographic footprints of past climate change. Proceedings of the National Academy of Sciences, 109(36), E2382–E2390. doi:10.1073/pnas.1210506109
Stukenbrock, E. H., Christiansen, F. B., Hansen, T. T., Dutheil, J. Y., & Schierup, M. H. (2012). Fusion of two divergent fungal individuals led to the recent emergence of a unique widespread pathogen species. Proceedings of the National Academy of Sciences, 109(27), 10954–10959. doi:10.1073/pnas.1201403109
Hvilsom, C., Qian, Y., Bataillon, T., Li, Y., Mailund, T., Salle, B., … Schierup, M. H. (2012). Extensive X-linked adaptive evolution in central chimpanzees. Proceedings of the National Academy of Sciences, 109(6), 2054–2059. doi:10.1073/pnas.1106877109
Kong, A., Frigge, M. L., Masson, G., Besenbacher, S., Sulem, P., Magnusson, G., … Stefansson, K. (2012). Rate of de novo mutations and the importance of father’s age to disease risk. Nature, 488(7412), 471–475. doi:10.1038/nature11396
Prüfer, K., Munch, K., Hellmann, I., Akagi, K., Miller, J. R., Walenz, B., … Pääbo, S. (2012). The bonobo genome compared with the chimpanzee and human genomes. Nature, 486(7404), 527–531. doi:10.1038/nature11128
Scally, A., Dutheil, J. Y., Hillier, L. W., Jordan, G. E., Goodhead, I., Herrero, J., … Marques-Bonet, T. (2012). Insights into hominid evolution from the gorilla genome sequence. Nature, 483(7388), 169–175. doi:10.1038/nature10842
Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., … Papiol, S. (2012). Common variant at 16p11.2 conferring risk of psychosis. Molecular Psychiatry, 19(1), 108–114. doi:10.1038/mp.2012.157
Kruse, L. V., Nyegaard, M., Christensen, U., Møller-Larsen, S., Haagerup, A., Deleuran, M., … Børglum, A. D. (2012). A genome-wide search for linkage to allergic rhinitis in Danish sib-pair families. European Journal of Human Genetics, 20(9), 965–972. doi:10.1038/ejhg.2012.46
Pedersen, M. S., Benros, M. E., Agerbo, E., Børglum, A. D., & Mortensen, P. B. (2012). Schizophrenia in patients with atopic disorders with particular emphasis on asthma: A Danish population-based study. Schizophrenia Research, 138(1), 58–62. doi:10.1016/j.schres.2012.02.019
Fryland, T., Elfving, B., Christensen, J. H., Mors, O., Wegener, G., & Børglum, A. D. (2012). Electroconvulsive seizures regulates the Brd1 gene in the frontal cortex and hippocampus of the adult rat. Neuroscience Letters, 516(1), 110–113. doi:10.1016/j.neulet.2012.03.069
Elfving, B., Buttenschøn, H. N., Foldager, L., Poulsen, P. H. P., Andersen, J. H., Grynderup, M. B., … Mors, O. (2012). Depression, the Val66Met polymorphism, age, and gender influence the serum BDNF level. Journal of Psychiatric Research, 46(9), 1118–1125. doi:10.1016/j.jpsychires.2012.05.003
Christensen, J. H., Elfving, B., Müller, H. K., Fryland, T., Nyegaard, M., Corydon, T. J., … Børglum, A. D. (2012). The Schizophrenia and Bipolar Disorder associated BRD1 gene is regulated upon chronic restraint stress. European Neuropsychopharmacology, 22(9), 651–656. doi:10.1016/j.euroneuro.2012.01.005
Vassos, E., Steinberg, S., Cichon, S., Breen, G., Sigurdsson, E., Andreassen, O. A., … Collier, D. A. (2012). Replication Study and Meta-Analysis in European Samples Supports Association of the 3p21.1 Locus with Bipolar Disorder. Biological Psychiatry, 72(8), 645–650. doi:10.1016/j.biopsych.2012.02.040
Nyegaard, M., Overgaard, M. T., Søndergaard, M. T., Vranas, M., Behr, E. R., Hildebrandt, L. L., … Børglum, A. D. (2012). Mutations in Calmodulin Cause Ventricular Tachycardia and Sudden Cardiac Death. The American Journal of Human Genetics, 91(4), 703–712. doi:10.1016/j.ajhg.2012.08.015
Besenbacher, S., Mailund, T., & Schierup, M. H. (2012). Association Mapping and Disease: Evolutionary Perspectives. Evolutionary Genomics, 275–291. doi:10.1007/978-1-61779-585-5_11
Saetre, P., Grove, J., Børglum, A. D., Mors, O., Werge, T., Andreassen, O. A., … Jönsson, E. G. (2012). Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: No consistent evidence for an association in the nordic population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B(8), 981–986. doi:10.1002/ajmg.b.32104

2011

(1 publications)

Gregersen, N., Dahl, H. A., Buttenschøn, H. N., Nyegaard, M., Hedemand, A., Als, T. D., … Mors, O. (2011). A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene. European Journal of Human Genetics, 20(1), 84–90. doi:10.1038/ejhg.2011.148